Sonographic depiction of changes of tumor vascularity in response to various therapies

Ultrasound Quarterly

Volumn 21, Issue 2, 2005, Pages 61-67

  Niermann, Kenneth J ^a   Fleischer, Arthur C ^a   Donnelly, Edwin F ^a   Schueneman, Aaron J ^a   Geng, Ling ^a   Hallahan, Dennis E ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Blood flow; Cancer; Power doppler

Indexed keywords

ANGIOGENESIS INHIBITOR; SUNITINIB;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER RADIOTHERAPY; CANCER TRANSPLANTATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DOPPLER ECHOGRAPHY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LEWIS CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKINFOLD THICKNESS; STATISTICAL ANALYSIS; TUMOR VASCULARIZATION; TUMOR VOLUME;

ANGIOGENESIS INHIBITORS; ANIMALS; COMBINED MODALITY THERAPY; IN SITU NICK-END LABELING; INDOLES; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; PYRROLES; ULTRASONOGRAPHY, DOPPLER, COLOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 19544377651     PISSN: 08948771     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996;86:353-364.
2. Folkman J. Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. N Engl J Med. 1995; 333:1757-1763.
3. Donnelly EF, Geng L, Wojcicki WE, et al. Quantified power Doppler US of tumor blood flow correlates with microscopic quantification of tumor blood vessels. Radiology. 2001;219:166-170.
4. Bartolozzi C, Lencioni R, Paolicchi A, et al. Differentiation of hepatocellular adenoma and focal nodular hyperplasia of the liver: comparison of power Doppler imaging and conventional color Doppler sonography. Eur Radiol. 1997;7:1410-1415.
5. Hosoki T, Mitomo M, Chor S, et al. Visualization of tumor vessels in hepatocellular carcinoma. Power Doppler compared with color Doppler and angiography. Acta Radiol. 1997;38:422-427.
6. Fleischer AC, Wojcicki WE, Donnelly EF, et al. Quantified color Doppler sonography of tumor vascularity in an animal model. J Ultrasound Med. 1999;18:547-551.
7. Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol. 2002;29(6 Suppl 16):15-18.
8. Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res. 1989;49:6449-6465.
9. Prewett M, Huber J, Li Y, et al. Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors. Cancer Res. 1999;59:5209-5218.
10. Schueneman AJ, Himmelfarb E, Geng L, et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res. 2003;63:4009-4016.
11. Hallahan D, Kuchibhotla J, Wyble C. Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium. Cancer Res. 1996;56:5150-5155.
12. Jahroudi N, Ardekani AM, Greenberger JS. Ionizing irradiation increases transcription of the von Willebrand factor gene in endothelial cells. Blood. 1996;88:3801-3814.
13. Gorski DH, Beckett MA, Jaskowiak NT, et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res. 1999;59:3374-3378.
14. Witte L, Fuks Z, Haimovitz-Friedman A, et al. Effects of irradiation on the release of growth factors from cultured bovine, porcine, and human endothelial cells. Cancer Res. 1989;49:5066-5072.
15. Bertram JS, Janik P. Establishment of a cloned line of Lewis Lung Carcinoma cells adapted to cell culture. Cancer Lett. 1980;11:63-73.
16. Hallahan DE, Mauceri HJ, Seung LP, et al. Spatial and temporal control of gene therapy using ionizing radiation. Nat Med. 1995;1:786-791.
17. Mendel DB, Laird AD, Xin X, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res. 2003;9:327-337.
18. Hemmerlein B, Kugler A, Özisik R, et al. Vascular endothelial growth factor expression, angiogenesis, and necrosis in renal cell carcinomas. Virchows Arch. 2001;439:645-652.
19. Brasch R, Li KCP. In vivo monitoring of tumor angiogenesis with MR imaging. Acad Radiol. 2000;7:812-823.
20. Alavi A, Kung JW, Zhuang H. Implications of PET based molecular imaging on the current and future practice of medicine. Semin Nucl Med. 2004;34:56-69.
21. Haubner R, Wester HJ, Burkhart F, et al. Glycosylated RGD-containing peptides: Tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001;42:326-336.
22. Becker AC, Hessenius K, Licha K, et al. Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands. Nat Biotechnol. 2001;19:327-331.
23. Weissleder R. Ntziachristos. Shedding light into live molecular targets. Nat Med. 2003;9:123-128.
24. Davidoff AM, Nathwani AC. Antiangiogenic gene therapy for cancer treatment. Curr Hematol Rep. 2004;3:267-273.
25. Carmeliet P. Manipulating angiogenesis in medicine. J Intern Med. 2004; 255:538-561.
26. Chen Y, Okunieff P. Radiation and third-generation chemotherapy. Hematol Oncol Clin North Am. 2004;18:55-80.
27. Wachsberger P, Burd R, Dicker AP. Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: exploring mechanisms of interaction. Clin Cancer Res. 2003;9:1957-1971.