Fluorous mixture synthesis of fused-tricyclic hydantoins. Use of a redundant tagging strategy on fluorinated substrates

Journal of Organic Chemistry

Volumn 70, Issue 11, 2005, Pages 4470-4473

  Manku, Sukhdev ^a   Curran, Dennis P ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MIXTURES; SUBSTRATES; SYNTHESIS (CHEMICAL);

REGIOISOMERIC MIXTURES; SELECTIVITY; TRICYCLIC HYDANTOINS;

KETONES;

3 TRIFLUOROMETHYLPHENYLALANINE; 3 TRIMETHYLSILYL PROPARGYL ALCOHOL; 3,4 DIFLUOROPHENYLALANINE; 4 FLUOROPHENYLALANINE; 4 TRIFLUOROMETHYLPHENYLALANINE; ALANINE; ALCOHOL DERIVATIVE; AMINO ACID; FLUORINE DERIVATIVE; HYDANTOIN DERIVATIVE; LEUCINE; NORVALINE; PHENYLALANINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ESTERIFICATION; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; THIN LAYER CHROMATOGRAPHY;

AMINO ACIDS; CHEMISTRY, ORGANIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDANTOINS; HYDROCARBONS, FLUORINATED; MOLECULAR STRUCTURE;

EID: 19544368155     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0502596     Document Type: Article

References (25)

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2. (b) Zhang, W.; Luo, Z.; Hiu-Tung Chen, C.; Curran, D. P. J. Am. Chem. Soc. 2002, 124, 10443-10450.
3. (c) Zhang, Q.; Lu, H.; Richard, C.; Curran, D. P. J. Am. Chem. Soc., 2004, 126, 36-37.
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6. (a) Curran, D. P. Synlett 2001, 1488-1496.
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15. (c) DPC holds an equity interest in this company.
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