New cytotoxic bisindole alkaloids with protein tyrosine kinase inhibitory activity from a myxomycete Lycogala epidendrum

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 11, 2005, Pages 2776-2780

  Hosoya, Takahiro ^a   Yamamoto, Yukinori ^b   Uehara, Yoshimasa ^c   Hayashi, Masahiko ^d   Komiyama, Kanki ^d   Ishibashi, Masami ^a  

^a CHIBA UNIVERSITY   (Japan)

^b National Institute of Infectious Diseases ^*  (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d KITASATO INSTITUTE   (Japan)

Author keywords

Bisindole; Cytotoxicity; Lycogala epidendrum; Myxomycete; Tyrosine kinase inhibitor

Indexed keywords

5,6 DIHYDROXYACRYRIAFLAVIN A; 6 HYDROXYSTAUROSPORINONE; ARCYRIAFLAVIN A; ARCYRIAFLAVIN B; ARCYRIARUBIN A; INDOLE ALKALOID; INDOLE DERIVATIVE; LYCOGARIC ACID; LYCOGARUBIN A; LYCOGARUBIN B; LYCOGARUBIN C; PROTEIN TYROSINE KINASE; STAUROSPORINONE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN KB; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SYNTHESIS; ENZYME INHIBITION; HELA CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYCOGALA EPIDENDRUM; MYXOMYCETES; SPECTROSCOPY; STRUCTURE ANALYSIS;

ALKALOIDS; ANIMALS; ENZYME INHIBITORS; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MYXOMYCETES; NIH 3T3 CELLS; PROTEIN-TYROSINE KINASES;

EPIDENDRUM; LYCOGALA EPIDENDRUM;

EID: 19544366773     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.103     Document Type: Article

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