Dilution method to refold bacterially expressed recombinant Der f 2 and Der p 2 to exhibit the secondary structure and histamine-releasing activity of natural allergens

International Archives of Allergy and Immunology

Volumn 137, Issue 1, 2005, Pages 1-8

  Takai, Toshiro ^a   Takaoka, Masatoshi ^b   Yasueda, Hiroshi ^c   Okumura, Ko ^a   Ogawa, Hideoki ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b SAITAMA INSTITUTE OF PUBLIC HEALTH   (Japan)

^c SAGAMIHARA NATIONAL HOSPITAL   (Japan)

Author keywords

Circular dichroism; Der f 2; Der p 2; Dilution; Histamine release; House dust mites; Inclusion bodies; Recombinant allergens; Refolding

Indexed keywords

BUFFER; EPITOPE; HISTAMINE; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; UREA; ALLERGEN; DERMATOPHAGOIDES FARINAE ANTIGEN F 2; DERMATOPHAGOIDES PTERONYSSINUS ANTIGEN P 2; DNA; RECOMBINANT PROTEIN;

ALLERGENICITY; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BACTERIUM; BASOPHIL; CIRCULAR DICHROISM; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COST BENEFIT ANALYSIS; DIALYSIS; DILUTION; HISTAMINE RELEASE; MITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; SOLUBILIZATION; STRUCTURE ANALYSIS; ANIMAL; CHEMISTRY; ESCHERICHIA COLI; GENETICS; IMMUNOLOGY; MOLECULAR CLONING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PYROGLYPHIDAE;

ALLERGENS; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; CIRCULAR DICHROISM; CLONING, MOLECULAR; DNA; ESCHERICHIA COLI; HISTAMINE RELEASE; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PYROGLYPHIDAE; RECOMBINANT PROTEINS;

EID: 19444380994     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000084607     Document Type: Article

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