Local injection of infliximab for the treatment of perianal crohn's disease

Diseases of the Colon and Rectum

Volumn 48, Issue 4, 2005, Pages 768-774

  Poggioli, G ^a   Laureti, S ^a   Pierangeli, F ^a   Rizzello, F ^a   Ugolini, F ^a   Gionchetti, P ^a   Campieri, M ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Crohn's perianal disease; Infliximab; Local injection

Indexed keywords

INFLIXIMAB; GASTROINTESTINAL AGENT; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANUS FISTULA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DRUG EFFICACY; DRUG INFUSION; DRUG RESPONSE; DRUG SAFETY; HUMAN; ILEITIS; INJECTION SITE REACTION; PROCTITIS; SAMPLE SIZE; SCORING SYSTEM; SEPSIS; TREATMENT CONTRAINDICATION; TREATMENT OUTCOME; ANUS DISEASE; CLINICAL TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; WOUND HEALING;

ANTIBODIES, MONOCLONAL; ANUS DISEASES; CROHN DISEASE; GASTROINTESTINAL AGENTS; HUMANS; INJECTIONS, SUBCUTANEOUS; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA; WOUND HEALING;

EID: 19444380965     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10350-004-0832-4     Document Type: Article

References (21)

1. P Buchmann MR Keighley RN Allan H Thompson J Alexander-Williams 1980 Natural history of perianal Crohn's disease. Ten years follow-up: a plea for conservatism Am J Surg 140 642
2. PR Williamson MD Hellinger SW Larach A Ferrara 1995 Twenty-year review of the surgical management of perianal Crohn's disease Dis Colon Rectum 38 389 92
3. DA Schwartz JH Pemberton WS Sandborn 2001 Diagnosis and treatment of perianal fistulas in Crohn's disease Ann Intern Med 135 906 18
4. RF McKee RA Keenan 1996 Perianal Crohn's disease. It is all bad news? Dis Colon Rectum 39 136 42
5. SR Targan SB Hanauer SJ Deventer 1997 A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease N Engl J Med 337 1029 35
6. R Cohen J Tsang S Hanauer 2000 Infliximab in Crohn's disease: first anniversary clinical experience Am J Gastroenterol 95 3469 77
7. P Rutgeers G D'Haens S Targan 1999 Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease Gastroenterology 117 761 9
8. DH Present P Rutgeers S Targan 1999 Infliximab for the treatment of fistulas in patients with Crohn's disease N Engl J Med 340 1398 405
9. LS Toy EJ Scherl A Kornbluth 2000 Complete bowel obstruction following initial response to infliximab therapy for Crohn's disease: a series of a newly described complication Gastroenterology 118 569
10. ® does not abolish the need for surgery in fistulizing Crohn's disease Dis Colon Rectum 45 771 5
11. S Lichtiger 2001 Healing of perianal fistulae by local injection of antibody to TNF Gastroenterology 120 (Suppl) A3154
12. WJ Sandborn VW Fazio BG Feagan SB Hanauer 2003 American Gastroenterological Association Clinical Practice Committee. Technical review of perianal Crohn's disease Gastroenterology 125 1508 30
13. P Marchesa TL Hull VW Fazio 1998 Advancement sleeve flaps for treatment of severe perianal Crohn's disease Br J Surg 85 1695 8
14. SB Hanauer BG Feagan GR Lichtenstein 2002 Maintenance Infliximab for Crohn's disease: the ACCENT I randomized trial Lancet 359 1541 9
15. F Cornillie D Shealy G D'Haens 2001 Infliximab induces potent anti-inflammatory and local activity, but no systemic immune suppression in patients with Crohn's disease Aliment Pharmacol Ther 15 463 73
16. JA Spencer K Chapple D Wilson J Ward AC Windsor NS Ambrose 1998 Outcome after surgery for perianal fistula: predictive value of MR imaging AJR Am J Roentgenol 171 403 6
17. RG Beets-Tan GL Beets AG van der Hoop 2001 Preoperative MR imaging of anal fistulas: does it really help the surgeon? Radiology 218 75 84
18. G Van Assche D Vanbeckevoort D Bielen 2003 Magnetic resonance imaging of the effects of infliximab on perianal fistulizing Crohn's disease Am J Gastroenterol 98 332 9
19. DA Schwartz MJ Wiersema ID Norton 2001 A comparison of endoscopic ultrasound, magnetic resonance imaging, and exam under anesthesia for evaluation of Crohn's perianal fistulas Gastroenterology 121 1064 72
20. SJ Bell S Halligan AC Windsor AB Williams P Wiesel MA Kamm 2003 Response of fistulating Crohn's disease to infliximab treatment assessed by magnetic resonance imaging Aliment Pharmacol Ther 17 187 93
21. DA Schwartz JH Pemberton WJ Sandborn 2001 Diagnosis and treatment of perianal fistulas in Crohn's disease Ann Intern Med 135 906 18