Mucosal and systemic antibody responses and protection induced by a prime/boost rotavirus-DNA vaccine in a gnotobiotic pig model

Vaccine

Volumn 23, Issue 30, 2005, Pages 3925-3936

  Yuan, Lijuan ^a   Azevedo, Marli S P ^a   Gonzalez, Ana M ^a   Jeong, Kwang Il ^a   Van Nguyen, Trang ^a   Lewis, Peggy ^a   Iosef, Cristiana ^b   Herrmann, John E ^c   Saif, Linda J ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c TUFTS UNIVERSITY   (United States)

Author keywords

DNA vaccine; Gnotobiotic pigs; Rotavirus

Indexed keywords

DNA VACCINE; LIVE VACCINE; ROTAVIRUS VACCINE; UNCLASSIFIED DRUG; VIRUS INNER CAPSID 6 VACCINE; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DIARRHEA; GNOTOBIOTICS; HELPER CELL; IMMUNIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ROTAVIRUS; STATISTICAL SIGNIFICANCE; SWINE; VIRUS CAPSID; VIRUS SHEDDING; VIRUS STRAIN; VIRUS VIRULENCE;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, VIRAL; DIARRHEA; ENZYME-LINKED IMMUNOSORBENT ASSAY; GERM-FREE LIFE; HUMANS; IMMUNITY, MUCOSAL; IMMUNIZATION SCHEDULE; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTESTINES; KINETICS; LYMPHATIC SYSTEM; PLAQUE ASSAY; PLASMIDS; ROTAVIRUS; ROTAVIRUS INFECTIONS; ROTAVIRUS VACCINES; SWINE; VACCINES, DNA; VIRUS SHEDDING;

EID: 19444372776     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.03.009     Document Type: Article

References (43)

1. U.D. Parashar, E.G. Hummelman, J.S. Bresee, M.A. Miller, and R.I. Glass Global illness and deaths caused by rotavirus disease in children Emerg Infect Dis 9 2003 565 572
2. P.A. Offit, R.D. Shaw, and H.B. Greenberg Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to surface proteins vp3 and vp7 J Virol 58 1986 700 703
3. M.K. Estes Rotaviruses and their replication D.M. Howley P.M. Ka Fields virology 4th ed. 2001 Lippincott-Raven & Wilkins Publishers Philadelphia, PA 1747 1786
4. S.M. Matsui, E.R. Mackow, and H.B. Greenberg Molecular determinant of rotavirus neutralization and protection Adv Virus Res 36 1989 181 214
5. J.W. Burns, M. Siadat-Pajouh, A.A. Krishnaney, and H.B. Greenberg Protective effect of rotavirus VP6-specific IgA monoclonal antibodies that lack neutralizing activity Science 272 1996 104 107
6. A. Coste, J.C. Sirard, K. Johansen, J. Cohen, and J.P. Kraehenbuhl Nasal immunization of mice with virus-like particles protects offspring against rotavirus diarrhea J Virol 74 2000 8966 8971
7. S.C. Chen, E.F. Fynan, and H.L. Robinson Protective immunity induced by rotavirus DNA vaccines Vaccine 15 1997 899 902
8. S.C. Chen, D.H. Jones, and E.F. Fynan Protective immunity induced by oral immunization with a rotavirus DNA vaccine encapsulated in microparticles J Virol 72 1998 5757 5761
9. K. Yang, S. Wang, and K.O. Chang Immune responses and protection obtained with rotavirus VP6 DNA vaccines given by intramuscular injection Vaccine 19 2001 3285 3291
10. J.E. Herrmann, S.C. Chen, and D.H. Jones Immune responses and protection obtained by oral immunization with rotavirus VP4 and VP7 DNA vaccines encapsulated in microparticles Virology 259 1999 148 153
11. R.L. Ward, M.M. McNeal, and J.F. Sheridan Development of an adult mouse model for studies on protection against rotavirus J Virol 64 1990 5070 5075
12. L. Saif, L. Yuan, L. Ward, and T. To Comparative studies of the pathogenesis, antibody immune responses, and homologous protection to porcine and human rotaviruses in gnotobiotic piglets Adv Exp Med Biol 412 1997 397 403
13. L. Yuan, L.A. Ward, B.I. Rosen, T.L. To, and L.J. Saif Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease J Virol 70 1996 3075 3083
14. L. Yuan, A. Geyer, and D.C. Hodgins Intranasal administration of 2/6-rotavirus-like particles with mutant Escherichia coli heat-labile toxin (LT-R192G) induces antibody-secreting cell responses but not protective immunity in gnotobiotic pigs J Virol 74 2000 8843 8853
15. L. Yuan, C. Iosef, and M.S. Azevedo Protective immunity and antibody-secreting cell responses elicited by combined oral attenuated Wa human rotavirus and intranasal Wa 2/6-VLPs with mutant Escherichia coli heat-labile toxin in gnotobiotic pigs J Virol 75 2001 9229 9238
16. C. Iosef, T. Van Nguyen, and K. Jeong Systemic and intestinal antibody secreting cell responses and protection in gnotobiotic pigs immunized orally with attenuated Wa human rotavirus and Wa 2/6-rotavirus-like-particles associated with immunostimulating complexes Vaccine 20 2002 1741 1753
17. M.S. Azevedo, L. Yuan, and C. Iosef Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protection Clin Diagn Lab Immunol 11 2004 12 20
18. T.V. Nguyen, C. Iosef, and K. Jeong Protection and antibody responses to oral priming by attenuated human rotavirus followed by oral boosting with 2/6-rotavirus-like particles with immunostimulating complexes in gnotobiotic pigs Vaccine 21 2003 4059 4070
19. C.M. O'Neal, S.E. Crawford, M.K. Estes, and M.E. Conner Rotavirus virus-like particles administered mucosally induce protective immunity J Virol 71 1997 8707 8717
20. C.M. O'Neal, J.D. Clements, M.K. Estes, and M.E. Conner Rotavirus 2/6 virus like particles administered intranasally with cholera toxin, Escherichia coli heat-labile toxin (LT), and LT-R192G induce protection from rotavirus challenge J Virol 72 1998 3390 3393
21. S.K. Eo, M. Gierynska, A.A. Kamar, and B.T. Rouse Prime-boost immunization with DNA vaccine: mucosal route of administration changes the rules J Immunol 166 2001 5473 5479
22. M. Premenko-Lanier, P.A. Rota, and G. Rhodes DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate Virology 307 2003 67 75
23. Y. Yasutomi, H.L. Robinson, and S. Lu Simian immunodeficiency virus-specific cytotoxic T-lymphocyte induction through DNA vaccination of rhesus monkeys J Virol 70 1996 678 681
24. L.A. Ward, B.I. Rosen, L. Yuan, and L.J. Saif Pathogenesis of an attenuated and a virulent strain of group A human rotavirus in neonatal gnotobiotic pigs J Gen Virol 77 1996 1431 1441
25. L. Yuan, S.Y. Kang, L.A. Ward, T.L. To, and L.J. Saif Antibody-secreting cell responses and protective immunity assessed in gnotobiotic pigs inoculated orally or intramuscularly with inactivated human rotavirus J Virol 72 1998 330 338
26. L.A. Ward, L. Yuan, B.I. Rosen, T.L. To, and L.J. Saif Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model Clin Diagn Lab Immunol 3 1996 342 350
27. E.H. Bohl, L.J. Saif, K.W. Theil, A.G. Agnes, and R.F. Cross Porcine pararotavirus: detection, differentiation from rotavirus, and pathogenesis in gnotobiotic pigs J Clin Microbiol 15 1982 312 319
28. R.C. Meyer, E.H. Bohl, and E.M. Kohler Procurement and maintenance of germ-free swine for microbiological investigations Appl Microbiol 12 1964 295 300
29. V. Parreno, D.C. Hodgins, and L. de Arriba Serum and intestinal isotype antibody responses to Wa human rotavirus in gnotobiotic pigs are modulated by maternal antibodies J Gen Virol 80 1999 1417 1428
30. W.K. Chen, T. Campbell, J. VanCott, and L.J. Saif Enumeration of isotype-specific antibody-secreting cells derived from gnotobiotic piglets inoculated with porcine rotaviruses Vet Immunol Immunopathol 45 1995 265 284
31. T.L. To, L.A. Ward, L. Yuan, and L.J. Saif Serum and intestinal isotype antibody responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease J Gen Virol 79 1998 2661 2672
32. P.S. Paul, W.L. Mengeling, C.E. Malstrom, and R.A. Van Deusen Production and characterization of monoclonal antibodies to porcine immunoglobulin gamma, alpha, and light chains Am J Vet Res 50 1989 471 479
33. E.H. Bohl, K.W. Theil, and L.J. Saif Isolation and serotyping of porcine rotaviruses and antigenic comparison with other rotaviruses J Clin Microbiol 19 1984 105 111
34. S. Ishida, N. Feng, B. Tang, J.M. Gilbert, and H.B. Greenberg Quantification of systemic and local immune responses to individual rotavirus proteins during rotavirus infection in mice J Clin Microbiol 34 1996 1694 1700
35. S.I. Ishida, N. Feng, J.M. Gilbert, B. Tang, and H.B. Greenberg Immune responses to individual rotavirus proteins following heterologous and homologous rotavirus infection in mice J Infect Dis 175 1997 1317 1323
36. L. Yuan, S.I. Ishida, and S. Honma Homotypic and heterotypic serum isotype-specific antibody responses to rotavirus nonstructural protein 4 and viral protein (VP) 4 VP6, and VP7 in infants who received selected live oral rotavirus vaccines J Infect Dis 189 2004 1833 1845
37. N.A. Doria-Rose, C. Ohlen, and P. Polacino Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge J Virol 77 2003 11563 11577
38. L.J. Patterson, N. Malkevitch, and D. Venzon Protection against mucosal simian immunodeficiency virus SIV(mac251) challenge by using replicating adenovirus-SIV multigene vaccine priming and subunit boosting J Virol 78 2004 2212 2221
39. A.M. Gonzalez, T.V. Nguyen, and M.S. Azevedo Antibody responses to human rotavirus (HRV) in gnotobiotic pigs following a new prime/boost vaccine strategy using oral attenuated HRV priming and intranasal VP2/6 rotavirus-like particle (VLP) boosting with ISCOM Clin Exp Immunol 135 2004 361 372
40. A. Bertolotti-Ciarlet, M. Ciarlet, S.E. Crawford, M.E. Conner, and M.K. Estes Immunogenicity and protective efficacy of rotavirus 2/6-virus-like particles produced by a dual baculovirus expression vector and administered intramuscularly, intranasally, or orally to mice Vaccine 21 2003 3885 3900
41. F.R. Esquivel, S. Lopez, X.L. Guitierrez, and C. Arias The internal rotavirus protein VP6 primes for an enhanced neutralizing antibody response Arch Virol 145 2000 813 825
42. D.R. Milich, A. McLachlan, G.B. Thornton, and J.L. Hughes Antibody production to the nucleocapsid and envelope of the hepatitis B virus primed by a single synthetic T cell site Nature 329 1987 547 549
43. P.A. Scherle, and W. Gerhard Differential ability of B cells specific for external vs. internal influenza virus proteins to respond to help from influenza virus-specific T-cell clones in vivo Proc Natl Acad Sci USA 85 1988 4446 4450