Bupropion-induced convulsions: Preclinical evaluation of antiepileptic drugs

Epilepsy Research

Volumn 64, Issue 1-2, 2005, Pages 13-22

  Tutka, Piotr ^a   Mróz, Tomasz ^a   Klucha, Katarzyna ^a   Piekarczyk, Małgorzata ^a   Wielosz, Marian ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Antiepileptic drugs; Bupropion; Clonazepam; Gabapentin; Seizures; Smoking cessation

Indexed keywords

AMFEBUTAMONE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLONAZEPAM; DIAZEPAM; ETHOSUXIMIDE; FELBAMATE; GABAPENTIN; LAMOTRIGINE; PHENOBARBITAL; PHENYTOIN; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CLONIC SEIZURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; DRUG POTENCY; LOCOMOTION; MALE; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTICONVULSANTS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BEHAVIOR, ANIMAL; BUPROPION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; MALE; MICE; MOTOR ACTIVITY; RANDOM ALLOCATION; ROTAROD PERFORMANCE TEST; SEIZURES;

EID: 19444368384     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2005.01.006     Document Type: Article

References (28)

1. A clinical practice guideline for treating tobacco use and dependence, 2000. A US Public Health Service report. The Tobacco Use and Dependence Clinical Practice Guideline Panel, Staff, and Consortium Representatives, JAMA 283, 3244-3254.
2. J.S. Ahluwalia, K.J. Harris, D. Catley, K.S. Okuyemi, and M.S. Mayo Sustained-release bupropion for smoking cessation in African Americans: a randomized controlled trial JAMA 288 2002 468 474
3. J.A. Ascher, J.O. Cole, J.N. Colin, J.P. Feighner, R.M. Ferris, H.C. Fibiger, R.N. Golden, P. Martin, W.Z. Potter, and E. Richelson Bupropion: a review of its mechanism of antidepressant activity J. Clin. Psychiatry 56 1995 395 401
4. C.R. Balit, C.N. Lynch, and G.K. Isbister Bupropion poisoning: a case series Med. J. Aust. 178 2003 61 63
5. M.G. Belson, and T.R. Kelley Bupropion exposures: clinical manifestations and medical outcome J. Emerg. Med. 23 2002 223 230
6. N.L. Benowitz, and M. Wilson Peng Non-nicotine pharmacotherapy for smoking essation CNS Drugs 13 2000 262 285
7. J. Davidson Seizures and bupropion: a review J. Clin. Psychiatry 50 1989 256 261
8. N.W. Dunham, and T.S. Miya A note on a simple approach for determining neurological deficits in rats and mice J. Am. Pharmacol. Assoc. 46 1957 208 209
9. D.L. Dunner, S. Zisook, A.A. Billow, S.R. Batey, J.A. Johnston, and J.A. Ascher A prospective safety surveillance study for bupropion sustained-release in the treatment of depression J. Clin. Psychiatry 59 1998 366 373
10. C.R. Harris, J. Gualtieri, and G. Stark Fatal bupropion overdose J. Toxicol. Clin. Toxicol. 35 1997 321 324
11. J.T. Hays, R.D. Hurt, N.A. Rigotti, R. Niaura, D. Gonzales, M.J. Durcan, D.P. Sachs, T.D. Wolter, A.S. Buist, J.A. Johnston, and J.D. White Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation: a randomized, controlled trial Ann. Intern. Med. 135 2001 423 433
12. J.R. Hughes, M.G. Goldstein, R.D. Hurt, and S. Shiffman Recent advances in the pharmacotherapy of smoking JAMA 281 1999 72 76
13. J.A. Johnston, C.G. Lineberry, J.A. Ascher, J. Davidson, M.A. Khayrallah, J.P. Feighner, and P. Stark A 102 center prospective study of seizure in association with bupropion J. Clin. Psychiatry 52 1991 450 456
14. D.E. Jorenby, S.J. Leischow, M.A. Nides, S.I. Rennard, J.A. Johnston, A.R. Hughes, S.S. Smith, M.L. Muramoto, D.M. Daughton, K. Doan, M.C. Fiore, and T.B. Baker A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation N. Engl. J. Med. 340 1999 685 691
15. R.L. Krall, J.K. Penry, B.G. White, H.J. Kupferberg, and E.A. Swinyard Antiepileptic drug development. II. Anticonvulsant drug screening Epilepsia 19 1978 409 428
16. J.T. Litchfield, and F. Wilcoxon A simplified method of evaluating dose-effect experiments J. Pharmacol. Exp. Ther. 96 1949 99 113
17. W. Löscher, and B. Nolting The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. IV. Protective indices Epilepsy Res. 9 1991 1 10
18. R.L. Macdonald, and K.M. Kelly Antiepileptic drug mechanisms of action Epilepsia 36 1995 S2 S12
19. A.W. Peck, W.C. Stern, and C. Watkinson Incidence of seizures during treatment with tricyclic antidepressant drugs and bupropion J. Clin. Psychiatry 44 1983 197 201
20. G.R. Pesola, and J. Avasarala Bupropion seizure proportion among new-onset generalized seizures and drug related seizures presenting to an emergency department J. Emerg. Med. 22 2002 235 239
21. G.D. Shah, and L.J. Hirsch Bitemporal epileptiform discharges induced by bupropion: a case report Clin. Neuropharmacol. 24 2001 304 306
22. D.V. Sheehan, J.B. Welch, and S.M. Fishman A case of bupropion-induced seizures J. Nerv. Ment. Dis. 174 1986 496 498
23. S. Shiffman, J.A. Johnston, M. Khayrallah, C.A. Elash, C.J. Gawltney, J.A. Paty, M. Gnys, G. Evoniuk, and J. DeVeaugh-Geiss The effect of bupropion on nicotine craving and withdrawal Psychopharmacology 148 2000 33 40
24. H.A. Spiller, E.A. Ramoska, E.P. Krenzelok, S.R. Sheen, D.J. Borys, D. Villalobos, S. Muir, and L. Jones-Easom Bupropion overdose: a 3-year multi-center retrospective analysis Am. J. Emerg. Med. 12 1994 43 45
25. A.B. Storrow Bupropion overdose and seizure Am. J. Emerg. Med. 12 1994 183 184
26. P. Tutka, B. Barczyński, and M. Wielosz Convulsant and anticonvulsant effects of bupropion in mice Eur. J. Pharmacol. 499 2004 117 120
27. P. Tutka, J. Łuszczki, Z. Kleinrok, K. Arent, and M. Wielosz Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice J. Neural. Transm. 109 2002 455 466
28. J. Van Wyck Fleet, P.J. Manberg, L.L. Miller, N. Harto-Truax, T. Sato, R.J. Fleck, W.C. Stern, and A.E. Cato Overview of clinically significant adverse reactions to bupropion J. Clin. Psychiatry 44 1983 191 196