Outcome of cabergoline treatment in men with prolactinoma: Effects of a 24-month treatment on prolactin levels, tumor mass, recovery of pituitary function, and semen analysis

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 4, 2004, Pages 1704-1711

  Colao, Annamaria ^a   Vitale, Giovanni ^a   Cappabianca, Paolo ^a   Briganti, Francesco ^a   Ciccarelli, Antonio ^a   De Rosa, Michele ^a   Zarrilli, Stefano ^a   Lombardi, Gaetano ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CABERGOLINE; CORTICOTROPIN; GONADOTROPIN; GROWTH HORMONE; PROLACTIN; TESTOSTERONE;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONVALESCENCE; DROWSINESS; DRUG EFFECT; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; GALACTORRHEA; GENDER; GENERAL CONDITION IMPROVEMENT; GROWTH HORMONE RELEASE; HEADACHE; HORMONE SUBSTITUTION; HUMAN; HYPOGONADISM; HYPOPHYSIS FUNCTION; HYPOPITUITARISM; MALE; NAUSEA; PRIORITY JOURNAL; PROLACTINOMA; PROSPECTIVE STUDY; SEMEN ANALYSIS; SPERM; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTOSTERONE BLOOD LEVEL; TREATMENT OUTCOME; TUMOR; TUMOR VOLUME; VISUAL DISORDER;

ADOLESCENT; ADULT; AGED; DOPAMINE AGONISTS; DRUG ADMINISTRATION SCHEDULE; ERGOLINES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PITUITARY GLAND; PITUITARY NEOPLASMS; PROLACTIN; PROLACTINOMA; SEMEN; TREATMENT OUTCOME;

EID: 1942537052     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-030979     Document Type: Article

References (33)

1. Colao A, Di Sarno A, Cappabianca P, Briganti F, Pivonello R, Di Somma C, Faggiano A, Biondi B, Lombardi G 2003 Gender differences in the prevalence, clinical features and response to cabergoline in hyperprolactinemia. Eur J Endocrinol 148:325-331
2. Di Sarno A, Landi ML, Cappabianca P, Di Salle F, Rossi FW, Pivonello R, Di Somma C, Faggiano A, Lombardi G, Colao A 2001 Resistance to cabergoline as compared to bromocriptine in hyperprolactinemia: prevalence, clinical definition and therapeutic strategy. J Clin Endocrinol Metab 86:5256-5261
3. Colao A, Di Sarno A, Sarnacchiaro F, Ferone D, Di Renzo GF, Merola B, Annunziato L, Lombard G 1997 Prolactinomas resistant to standard dopamine agonists respond to chronic cabergoline treatment. J Clin Endocrinol Metab 82:876-883
4. Biller BMK, Molitch ME, Vance ML, Cannistraro KB, Davis KR, Simons JA, Schoenfelder JR, Klibanski A 1996 Treatment of prolactin-secreting macroadenomas with the once-weekly dopamine agonist cabergoline. J Clin Endocrinol Metab 81:2338-2343
5. Colao A, Loche S, Cappa M, Di Sarno A, Landi ML, Samacchiaro F, Facciolll G, Lombardi G 1998 Prolactinomas in children and adolescents: clinical presentation and long-term follow-up. J Clin Endocrinol Metab 83:2777-2780
6. Cannavò S, Curtò L, Squadrito S, Almoto B, Vieni A, Trimarchi F 1999 A first choice treatment in patients with previously untreated prolactin-secreting pituitary adenoma. J Endocrinol Invest 22:354-359
7. Calle-Rodrigue RD, Giannini C, Scheithauer BW, Lloyd RV, Wollan PC, Kovacs KT, Stefaneanu L, Ebright AB, Abboud CF, Davis DH 1998 Prolactinomas in male and female patients: a comparative clinico-pathology study. Mayo Clin Proc 73:1046-1052
8. Delgrange E, Trouillas J, Maiter D, Donckier J, Tourniaire J 1997 Sex-related difference in the growth of prolactinomas: a clinical and proliferation marker study. J Clin Endocrinol Metab 82:2102-2107
9. Somma M, Beauregard H, Rasio E 1981 Le prolactinome chez l'homme: evaluation préopératoire de 40 patients. Neurochirurgie 27:37-39
10. Eversmann T, Eichinger R, Fahlbusch R, Rjosk HK, von Werder K 1981 Die hyperprolaktinämie beim mann: klinik und therapie. Schw Med Wochensch 111:1782-1789
11. Spark RF, Wills CA, O'Reilly G, Ransil BJ, Bergland R 1982 Hyperprolactinaemia in males with and without pituitary macroadenomas. Lancet 2:129-132
12. Hulting AL, Muhr C, Lundberg PO, Werner S 1985 Prolactinomas in men: clinical characteristics and the effect of bromocriptine treatment. Acta Medica Scandinava 217:101-109
13. Walsh JP, Pullan PT 1997 Hyperprolactinaemia in males: a heterogeneous disorder. Aust N Z J Med 27:385-390
14. Grisoli F, Vincentelli F, Jaquet P, Guibout M, Hassoun J, Farnarier P 1980 Prolactin secreting adenoma in 22 men. Surg Neurol 13:241-247
15. Berezin M, Shimon I, Hadani M 1995 Prolactinoma in 53 men: clinical characteristics and modes of treatment (male prolactinoma). J Endocrinol Invest 18:436-441
16. Di Somma C, Colao A, Di Sarno A, Klain M, Landi ML, Facciolli G, Pivonello R, Panza N, Salvatore M, Lombardi G 1998 Bone density and bone marker responses to dopamine agonist therapy in hyperprolactinemia males. J Clin Endocrinol Metab 83:807-813
17. Pinzone JJ, Katznelson L, Danila DC, Pauler DK, Miller CS, Klibanski A 2000 Primary medical therapy of micro-and macroprolactinomas in men. J Clin Endocrinol Metab 85:3053-3057
18. Verhelst J, Abs R, Maiter D, Vandeweghe M, Velkeniers B, Mockel J, Lamberigts G, Petrossians P, Coremans P, Mahler C, Stevenaert A, Verlooy J, Raftopoulos C, Beckers A 1999 Cabergoline in the treatment of hyperprolactinemia: a study in 455 patients. J Clin Endocrinol Metab 84:2518-2522
19. Colao A, De Rosa M, Sarnacchiaro F, Di Sarno A, Landi ML, Iervolino E, Zarrilli S, Merola B, Lombardi G 1996 Chronic treatment with CV 205-52 restores the gonadal function in hyperprolactinemic males. Eur J Endocrinol 135:548-552
20. De Rosa M, Colao A, Di Sarno A, Ferone D, Landi ML, Zarrilli S, Paesano L, Merola B, Lombardi G 1998 Cabergoline treatment rapidly improves gonadal function in hyperprolactinemic males: a comparison with bromocriptine. Eur J Endocrinol 138:286-293
21. De Rosa M, Zarrilli S, Vitale G, Di Somma C, Orio F, Tauchmanova' L, Lombardi G, Colao A 2004 Six months of treatment with cabergoline restores sexual potency in hyperprolactinemic males: an open longitudinal study monitoring nocturnal penile tumescence. J Clin Endocrinol Metab 89:621-625
22. Colao A, Di Sarno A, Landi ML, Scavuzzo F, Cappabianca P, Pivonello R, Volpe R, Di Salle F, Cirillo S, Annunziato L, Lombardi G 2000 Macroprolactinoma shrinkage during cabergoline treatment is greater in naive patients than in patients pretreated with other dopamine agonists: a prospective study in 110 patients. J Clin Endocrinol Metab 85:2247-2252
23. Ghigo E, Aimaretti G, Gianotti L, Bellone J, Arvat E, Camanni F 1996 New approach to the diagnosis of growth hormone deficiency in adults. Eur J Endocrinol 134:352-356
24. Colao A, Di Somma C, Pivonello R, Loche S, Aimaretti G, Cerbone G, Faggiano A, Corneli G, Ghigo E, Lombardi G 1999 Bone loss is correlated to the severity of growth hormone (GH) deficiency in adult patients with hypopituitarism. J Clin Endocrinol Metab 84:1919-1924
25. Colao A, Cerbone G, Pivonello R, Aimaretti G, Loche S, Di Somma C, Faggiano A, Corneli G, Ghigo E, Lombardi G 1999 The growth hormone (GH) response to arginine plus GH releasing hormone test is correlated to the severity of lipid profile abnormalities in adult patients with GH deficiency. J Clin Endocrinol Metab 84:1277-1282
26. Cappabianca P, Lodrini S, Felisati G, Peca C, Cozzi R, Di Sarno A, Cavallo LM, Giombini S, Colao A 2001 Cabergoline-induced CSF rhinorrhea in patients with macroprolactinoma: report of three cases. J Endocrinol Invest 24: 183-187
27. Colao A, Di Sarno A, Landi ML, Cirillo S, Sarnacchiaro F, Facciolli G, Pivonello R, Cataldi M, Merola B, Annunziato L, Lombardi G 1997 Long-term and low-dose treatment with cabergoline induces macroprolactinoma shrinkage. J Clin Endocrinol Metab 82:3574-3579
28. Colao A, Di Sarno A, Cappabianca P, Di Somma C, Pivonello R, Lombardi G 2003 Withdrawal of long-term cabergoline therapy for tumoral and non-tumoral hyperprolactinemia. N Engl J Med 349:2023-2033
29. World Health Organization 1999 Laboratory manual for the examination of human semen and semen-cervical mucus interaction. Cambridge, UK: Cambridge University Press
30. George LD, Nicolau N, Scanlon MF, Davies JS 2000 Recovery of growth hormone secretion following cabergoline treatment of macroprolactinomas. Clin Endocrinol (Oxf) 53:595-599
31. Growth Hormone Research Society (GRS) 1998 Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: summary statement of the Growth Hormone Research Society Workshop on adult growth hormone deficiency. J Clin Endocrinol Metab 83:379-381
32. Bartke A 1985 Male hamster endocrinology. In: Siegel HI, ed. The hamster: reproduction and behaviour. New York: Plenum Press; 73-98
33. Segal S, Yaffe H, Laufer N, Ben-David M 1979 Male hyperprolactinemia: effect on fertility. Fertil Steril 32:556-561