Studies on anti-Helicobacter pylori agents. Part 3: A novel, efficacious cephem derivative, FR193879

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 10, 2004, Pages 2627-2631

  Yoshida, Yoshiki ^a   Matsuda, Keiji ^a   Sasaki, Hiroshi ^a   Matsumoto, Yoshimi ^a   Matsumoto, Satoru ^a   Tawara, Shuichi ^a   Takasugi, Hisashi ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIINFECTIVE AGENT; CEPHEM DERIVATIVE; CHLORAMPHENICOL; FR 193879; METRONIDAZOLE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CROSS RESISTANCE; DOG; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG SYNTHESIS; HELICOBACTER PYLORI; HUMAN; MOUSE; NONHUMAN;

ACETAMIDES; ANIMALS; ANTI-BACTERIAL AGENTS; CEPHALOSPORINS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, BACTERIAL; DRUG STABILITY; GUINEA PIGS; HELICOBACTER PYLORI; MICE; MICROBIAL SENSITIVITY TESTS; PHARMACOKINETICS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TREATMENT OUTCOME;

CANIS FAMILIARIS; HELICOBACTER; HELICOBACTER PYLORI;

EID: 1942534230     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.068     Document Type: Article

References (14)

1. The Eurogast Study Group Lancet. 341:1993;1359-1362.
2. NIH consensus development panel on Helicobacter pylori in peptic ulcer disease. Helicobacter pylori in peptic ulcer disease. JAMA. 272:1994;65-69.
3. International Agency for Research on Cancer (WHO): Schistosomes, liver flukes and Helicobacter pylori. IARC Monogr. Eval. Carcinog. Risks Hum. 61:1994;218-220.
4. Lind T., Veldhuyzen van Zanten S.J.O., Unge P., Spiller R.C., Bayerdörffer E., Morain C.O., Wrangstadh M., Idström J.P. Gut. 37:1995;A4.
5. Logan R.P.H., Gummett P.A., Schaufelberger H.D., Greaves R.R.F.H., Mendelson G.M., Walker M.M., Thomas P.H., Baron J.H., Misiewicz J.J. Gut. 25:1994;323-326.
6. Tomas K.W.L., Augustine F.B.C., Joseph J.Y.S., Phyllis Y.L.Y., Sydney S.C.C. Helicobacter. 1:1996;57-61.
7. Moayyedi P., Sahay P., Tompkins D.S., Axon A.T.R. Eur. J. Gastroenterol. Hepatol. 7:1995;835-840.
8. Tonge K.A., Goddard A.F., Logan R.P.H., Gummett P.A., Harkey C.J., Misiewicz J.J., Baron J.H. Gastroenterology. 108:1995;A242. 5.
9. Penston J.G. Aliment. Pharmacol. Ther. 8:1994;369-389.
10. Yoshida Y., Matsuda K., Sasaki H., Matsumoto Y., Matsumoto S., Tawara S., Takasugi H. Bioorg. Med. Chem. 8:2000;2317-2335.
11. Yoshida Y., Matsuda K., Sasaki H., Matsumoto Y., Matsumoto S., Takasugi H. Bioorg. Med. Chem. Lett. 9:1999;3123-3126.
12. Niizato T., Suzuki H., Seto N., Ohishi K., Hayasaka H., Matsushita N. Chemotherapy (Tokyo). 40:1992;186-231.
13. Kobayashi F., Higashiyama N., Moriyama T., Nishimura K., Muraoka Y., Nara H. Chemotherapy (Tokyo). 37:1989;833-857.
14. D'Amico J.J., Harman M.W. J. Am. Chem. Soc. 77:1955;476-478.