L-arginine-mediated vasoreactivity in patients with a risk of stroke

Cerebrovascular Diseases

Volumn 17, Issue 2-3, 2004, Pages 128-133

  Zimmermann, Carolin ^a   Wimmer, Martin ^a   Haberl, Roman L ^a  

^a Krankenhaus Munich Harlaching   (Germany)

Author keywords

Cardiovascular risk factors; Endothelial dysfunction; Intima media thickness; L arginine mediated vasoreactivity; Stroke

Indexed keywords

ARGININE;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRAIN BLOOD FLOW; CARDIOVASCULAR RISK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DOPPLER ECHOGRAPHY; FEMALE; FLOW RATE; HUMAN; HYPERTENSION; HYPOTHESIS; MAJOR CLINICAL STUDY; MALE; MIDDLE CEREBRAL ARTERY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; STROKE;

EID: 1942531435     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000075781     Document Type: Article

References (27)

1. Schachinger V, Britten MB, Zeiher AM: Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000;101:1899-1906.
2. Suwaidi JA, Hamasaki S, Higano ST, Nishimura RA, Holmes DR Jr, Lerman A: Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 2000;101:948-954.
3. Cooke JP, Oka RK: Atherogenesis and the arginine hypothesis. Curr Atheroscler Rep 2001;3:252-259.
4. Cannon RO 3rd: Role of nitric oxide in cardiovascular disease: Focus on the endothelium. Clin Chem 1998;44:1809-1819.
5. Folsom AR, Rosamond WD, Shahar E, Cooper LS, Aleksic N, Nieto FJ, Rasmussen ML, Wu KK: Prospective study of markers of hemostatic function with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators. Circulation 1999;100:736-742.
6. Ridker PM, Stampfer MJ, Rifai N: Novel risk factors for systemic atherosclerosis: A comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA 2001;285:2481-2485.
7. O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr: Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999;340:14-22.
8. Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE: Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation 1997;96:1432-1437.
9. Schachinger V, Zeiher AM: Quantitative assessment of coronary vasoreactivity in humans in vivo. Circulation 1995;92:2087-2094.
10. Sumino H, Sato K, Sakamaki T, Masuda H, Nakamura T, Kanda T, Nagai R: Decreased basal production of nitric oxide in patients with heart disease. Chest 1998;113:317-322.
11. Drexler H, Zeiher AM, Meinzer K, Just H: Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine. Lancet 1991;338:1546-1550.
12. Calver A, Collier J, Vallance P: Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. J Clin Invest 1992;90:2548-2554.
13. Thorne S, Mullen MJ, Clarkson P, Donald AE, Deanfield JE: Early endothelial dysfunction in adults at risk from atherosclerosis: Different responses to L-arginine. J Am Coll Cardiol 1998;32:110-116.
14. Britten MB, Zeiher AM, Schachinger V: Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic options. J Intern Med 1999;245:315-327.
15. Tousoulis D, Davies GJ, Crake T, Toutouzas PC: Vasomotion and nitric oxide bioactivity in diseased coronary arteries. Heart 2002;87:320-321.
16. Taddei S, Virdis A, Mattei P, Ghiadoni L, Gennari A, Fasolo CB, Sudano I, Salvetti A: Aging and endothelial function in normotensive subjects and patients with essential hypertension. Circulation 1995;91:1981-1987.
17. Reutens DC, McHugh MD, Toussaint PJ, Evans AC, Gjedde A, Meyer E, Stewart DJ: Larginine infusion increases basal but not activated cerebral blood flow in humans. J Cereb Blood Flow Metab 1997;17:309-315.
18. Smulders RA, Aarsen M, Teerlink T, De Vries PM, Van Kamp GJ, Donker AJ, Stehouwer CD: Haemodynamic and biochemical responses to L-arginine and L-lysine infusions in normal subjects: L-arginine-induced vasodilatation cannot be explained by non-specific effects of cationic amino acids. Clin Sci (Lond) 1997;92:367-374.
19. Vallance P, Collier J, Moncada S: Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo. Cardiovasc Research 1989, 23:1053-1057.
20. Micieli G, Bosone D, Costa A, Cavallini A, Marcheselli S, Pompeo F, Nappi G: Opposite effects of L-arginine and nitroglycerin on cerebral blood velocity: Nitric oxide precursors and cerebral blood velocity. J Neurol Sci 1997;150:71-75.
21. Hankey GJ, Jamrozik K, Broadhurst RJ, Forbes S, Burvill PW, Anderson CS, Stewart-Wynne EG: Five-year survival after first-ever stroke and related prognostic factors in the Perth Community Stroke Study. Stroke 2000;31:2080-2086.
22. Adams HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh 3d EE: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993;24:35-41.
23. World Medical Association Declaration of Helsinki: Recommendations guiding physicians in biomedical research involving human subjects. Cardiovasc Res 1997;35:2-3.
24. Truelsen T, Lindenstrom E, Boysen G: Comparison of probability of stroke between the Copenhagen City Heart Study and the Framingham Study. Stroke 1994;25:802-807.
25. Kontos HA: Validity of cerebral blood flow calculations from velocity measurements. Stroke 1989;20:1-3.
26. 2 and L-arginine in patients with severe internal carotid artery stenosis; pre-and postsurgical evaluation with transcranial Doppler. J Neurol Sci 1999;163:153-158.
27. Kurz S, Harrison DG: Insulin and the arginine paradox. J Clin Invest 1997;99:369-370.