Initiation of Bacterial Killing by Two-Component Sensing of a "Death Peptide". Development of Antibiotic Tolerance in Streptococcus pneumoniae

Histidine Kinases in Signal Transduction

Volumn , Issue , 2002, Pages 365-375

  Novak, Rodger ^a   Tuomanen, Elaine ^b  

^a Vienna Biocenter   (Austria)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; ANTIGEN-ANTIBODY REACTIONS; BACTERIA; BACTERIOPHAGES; GENES; HYDROLASES; PEPTIDES; SIGNAL TRANSDUCTION;

ANTIBIOTIC TOLERANCES; BACTERIAL MEMBRANES; BACTERIAL POPULATION; HYDROLASE ACTIVITIES; PROGRAMMED CELL DEATHS; STREPTOCOCCUS PNEUMONIAE; TRANSPORT CHANNEL; TWO-COMPONENT SIGNAL TRANSDUCTION;

CELL DEATH;

EID: 1942521555     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012372484-7/50018-7     Document Type: Chapter

References (36)

1. Engelberg-Kulka H., Glaser G. Addiction modules and programmed cell death and antideath in bacterial cultures. Annu. Rev. Microbiol. 1999, 53:43-70.
2. Jensen R.B., Gerdes K. Programmed cell death in bacteria: Proteic plasmid stabilization systems. Mol. Microbiol. 1995, 17:205-210.
3. Lehnherr H., Maguin E., Jafri S., Yarmolinsky M.B. Plasmid addiction genes of bacteriophage P1: doc, which causes cell death on curing of prophage, and phd, which prevents host death when prophage is retained. J. Mol. Biol. 1993, 233:414-428.
4. Kolter R., Moreno F. Genetics of ribosomally synthesized peptide antibiotics. Annu. Rev. Microbiol. 1992, 46:141-163.
5. Jaffe A., Ogura T., Hiraga S. Effects of the ccd function of the F plasmid on bacterial growth. J. Bacteriol. 1985, 163:841-849.
6. Thisted T., Nielsen A.K., Gerdes K. Mechanism of post-segregational killing: Translation of Hok, SrnB and Pnd mRNAs of plasmids R1, F and R483 is activated by 3'-end processing. EMBO J. 1994, 13:1950-1959.
7. Novak R., Charpentier E., Braun J.S., Tuomanen E. Signal transduction by a death signal peptide: Uncovering the mechanism of bacterial killing by penicillin. Mol. Cell 2000, 5:49-57.
8. Weidel J., Pelzer H. Bag shaped macromolecules: A new look on bacterial cell walls. Adv. Enzymol. 1964, 26:193-232.
9. Tomasz A. Murein hydrolases: Enzymes in search of a physiological function. The Target of Penicillin 1983, 155-172. Walter de Gruyter, Washington, DC. R. Hakenbeck, J. Holtje, L.H. (Eds.).
10. Tomasz A., Albino A., Zanati E. Multiple antibiotic resistance in a bacterium with suppressed autolytic system. Nature 1970, 227:138-140.
11. Tomasz A., Holtje J.V. Murein hydrolases and the lytic and killing action of penicillin. Microbiology 1977, 209-215. American Society for Microbiology, Berlin. D. Schlesinger (Ed.).
12. Pearce B.J., Yin Y.B., Masure H.R. Genetic identification of exported proteins in Streptococcus pneumoniae. Mol. Microbiol. 1993, 9:1037-1050.
13. Williamson R., Tomasz A. Antibiotic-tolerant mutants of Streptococcus pneumoniae that are not deficient in autolytic activity. J. Bacteriol. 1980, 144:105-113.
14. Novak R., Henriques B., Charpentier E., Normark S., Tuomanen E. Emergence of vancomycin tolerance in Streptococcus pneumoniae. Nature 1999, 399:590-593.
15. Stock J.B., Ninfa A.J., Stock A.M. Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol. Rev. 1989, 53:450-490.
16. Throup J.P., Koretke K.K., Bryant A.P., Ingraham K.A., Chalker A.F., Ge Y., Marra A., Wallis N.G., Brown J.R., Holmes D.J., Rosenberg M., Burnham M.K. A genomic analysis of two-component signal transduction in Streptococcus pneumoniae. Mol. Microbiol. 2000, 35:566-576.
17. Parkinson J.S., Kofoid E.C. Communication modules in bacterial signaling proteins. Annu. Rev. Genet. 1992, 26:71-112.
18. Holman T.R., Wu Z., Wanner B.L., Walsh C.T. Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium. Biochemistry 1994, 33:4625-4631.
19. Walker J.E., Saraste M., Runswich M.J., Gay N.J. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases, and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J 1982, 1:945-951.
20. Ames G.F., Mimura C.S., Shyamala V. Bacterial periplasmic permeases belong to a family of transport proteins operating from Escherichia coli to human: Traffic ATPases. FEMS Microbiol. Rev. 1990, 6:429-446.
21. Hyde S.C., Emsley P., Hartshorn M.J., Mimmack M.M., Gileadi U., Pearce S.R., Gallagher M.P., Gill D.R., Hubbard R.E., Higgins C.F. Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport. Nature 1990, 346:362-365.
22. Linton K.J., Higgins C.F. The Escherichia coli ATP-binding cassette (ABC) proteins. Mol. Microbiol. 1998, 28:5-13.
23. Fuqua W.C., Winans S.C., Greenberg E.P. Quorum sensing in bacteria: The LuxR-LuxI family of cell density-responsive transcriptional regulators. J. Bacteriol. 1994, 176:269-275.
24. Kleerebezem M., Quadri L.E., Kuipers O.P., de Vos W.M. Quorum sensing by peptide pheromones and two component signal-transduction systems in Gram-positive bacteria. Mol. Microbiol. 1997, 24:895-904.
25. Hui F.M., Zhou L., Morrison D.A. Competence for genetic transformation in Streptococcus pneumoniae: Organization of a regulatory locus with homology to two lactococcin A secretion genes. Gene 1995, 153:25-31.
26. Kolter R., Moreno F. Genetics of ribosomally synthesized peptide antibiotics. Annu. Rev. Microbiol. 1992, 46:141-165.
27. Kornblum J., Kreiswirth B., Projan S.J., Ross H., Novick R.P. agr: A polycistronic locus regulating exoprotein synthesis in Staphylococcus aureus. Molecular Biology of the Staphylococci 1990, 373-402. VCH, Washington, DC. R.P. Novick (Ed.).
28. Gilmore M.S., Hoch J.A. Antibiotic resistance: A vancomycin surprise. Nature 1999, 399:524-525.
29. Hancock R.E.W. Peptide antibiotics. Lancet 1997, 349:418-422.
30. Moreillon P., Markiewicz Z., Nachman S., Tomasz A. Two bactericidal targets for penicillin in pneumococci: Autolysis-dependent and autolysis-independent killing mechanisms. Antimicrob. Agents Chemother. 1990, 34:33-39.
31. Moreillon P., Tomasz A. Penicillin resistance and defective lysis in clinical isolates of pneumococci: Evidence for two kinds of antibiotic pressure operating in the clinical environment. J. Infect. Dis. 1988, 157:1150-1157.
32. Cashel M., Gentry D.R., Hernandez V.J., Vinella D. The stringent response. Escherichia coli and Salmonella: Cellular and Molecular Biology 1996, ASM Press, New York. F.C. Neidhardt, R. Curtis, J.L. Ingraham, E.C.C. Lin, K.B. Low, B. Magasanik, W.S. Reznikoff, M. Riley, M. Schaechter, H.E. Umbarger (Eds.).
33. Brunskill E.W., Bayles K.W. Identification of LytSR-regulated genes from Staphylococcus aureus. J. Bacteriol. 1996, 178:5810-5812.
34. Groicher K.H., Firek B.A., Fujimoto D.F., Bayles K.W. The Staphylococcus aureus IrgAB operon modulates murein hydrolase activity and penicillin tolerance. J. Bacteriol. 2000, 182:1794-1801.
35. Bayles K.W. The bactericidal action of penicillin: New clues to an unsolved mystery. Trends Microbiol. 2000, 8:274-278.
36. Garcia P., Gonzalez M.P., Garcia E., Rubens L., Garcia J.L. Lyt B, a novel pneumococcal murein hydrolase essential for cell separation. Mol. Microbiol. 1999, 31:1275-1277.