Polycythemia Vera and Pregnancy: A Case Report with the Use of Hydroxyurea in the First Trimester

American Journal of Perinatology

Volumn 21, Issue 3, 2004, Pages 135-137

  Pata, Ozlem ^a,b   Tok, C Ekrem ^b   Yazici, Gurkan ^b   Pata, Cengiz ^b   Öz, A Utku ^b   Aban, Meral ^b   Dilek, Saffet ^b  

^a University of Mersin ^*  (Turkey)

^b MERSIN UNIVERSITY   (Turkey)

Author keywords

Hydroxyurea; Polycythemia vera; Pregnancy; Teratogeny

Indexed keywords

HYDROXYUREA;

ADULT; ARTICLE; CASE REPORT; FEMALE; FIRST TRIMESTER PREGNANCY; HEMATOCRIT; HUMAN; POLYCYTHEMIA VERA; PRIORITY JOURNAL; THROMBOCYTE COUNT; TREATMENT OUTCOME; VAGINAL DELIVERY;

ADULT; ANTINEOPLASTIC AGENTS; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; HYDROXYUREA; INFANT, NEWBORN; MALE; POLYCYTHEMIA VERA; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREGNANCY TRIMESTER, FIRST; PRENATAL DIAGNOSIS; TERATOGENS;

EID: 1942518916     PISSN: 07351631     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-823773     Document Type: Article

References (15)

1. Tefferi A, Solberg LA, Silverstein MN. A clinical up date in polycythemia vera and essential thrombocythemia. Am J Med 2000;109:141-149
2. Frezzato M, Ruggeri M, Castaman G, Rodeghiero F. Polycythemia vera and essential thrombocythemia in young patients. Haematologica 1993;78(suppl 2):11-17
3. Ferguson JE, Ueland K, Aronson WJ. Polycythemia rubra vera and pregnancy. Obstet Gynecol 1983;62(suppl):16S-20S
4. Griesshammer M, Bergmann L, Pearson T. Fertility, pregnancy and the management of myeloproliferative disorders. Baillieres Clin Haematol 1998;11:859-874
5. Crowley JP, Barcohana Y, Sturner WQ. Disseminated intravascular coagulation following first trimester abortion in polycythemia vera. Increased platelet count apparently contributed to fatal outcome. R I Med J 1987;70:109-112
6. Schmitt HJ, Becke K, Neidhart B. Epidural anesthesia for cesarean delivery in patient with polycythemia rubra vera and preeclampsia. Anesth Analg 2001;92: 1535-1537
7. Subtill D, Deruelle P, Trillot N, Jude B. Preclinical phase of polycythemia vera in pregnancy. Obstet Gynecol 2001;98(5 pt 2):945-947
8. Ruggeri M, Tosetto A, Castaman G, Rodeghiero F. Pulmonary embolism after pregnancy in a patient with polycythemia vera. Am J Hematol 2001;67:216-217
9. Kupferminc MJ, Eldor A, Steinman N, et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med 1999;340: 9-13
10. Jackson N, Shukri A, Ali K. Hydroxyurea treatment for chronic myeloid leukemia during pregnancy. Br J Haematol 1993;85:203-204
11. Asano Y, Okaniwa A. In utero morphological effects of hydroxyurea on the fetal development in Sprague-Dawley rats. Jikken Dobutsu 1987;36:143-149
12. Celiloglu M, Altinyurt S, Undar B. Hydroxyurea treatment for chronic myeloid leukemia during pregnancy. Acta Obstet Gynecol Scand 2000;79:803-804
13. Fadilah SA, Ahmad-Zailani H, Soon-Keng C, Norlaila M. Successful treatment of chronic myeloid leukemia during pregnancy with hydroxyurea. Leukemia 2002;16:1202-1203
14. Thauvin-Robinet C, Maingueneau C, Robert E, et al. Exposure to hydroxyurea during pregnancy: a case series. Leukemia 2001;15:1309-1311
15. Baykal C, Zengin N, Coskun F, Guler N, Ayhan A. Use of hydroxyurea and alpha-interferon in chronic myeloid leukemia during pregnancy: a case report. Eur J Gynaecol Oncol 2000;21:89-90