A 82Rb infusion system for quantitative perfusion imaging with 3D PET

Applied Radiation and Isotopes

Volumn 60, Issue 6, 2004, Pages 921-927

  Epstein, Neil J ^a   Benelfassi, Ahmed ^a   Beanlands, Rob S B ^a   DeKemp, Robert A ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

3D PET; Blood flow; Perfusion imaging; Positron emission tomography; Rubidium 82

Indexed keywords

COMPUTER SIMULATION; DRUG INFUSION; FEEDBACK CONTROL; POSITRON EMISSION TOMOGRAPHY;

INFUSION SYSTEMS; PATIENT INFUSION;

RADIOISOTOPES;

RUBIDIUM 82; STRONTIUM 82; DIAGNOSTIC AGENT; RUBIDIUM;

ARTICLE; FEEDBACK SYSTEM; FLOW RATE; GENERATOR; MODEL; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SIMULATION; THREE DIMENSIONAL IMAGING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CORONARY ARTERY DISEASE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; PERFUSION; REPRODUCIBILITY; SCINTISCANNING;

CORONARY DISEASE; HUMANS; INFUSIONS, INTRAVENOUS; PERFUSION; REPRODUCIBILITY OF RESULTS; RUBIDIUM RADIOISOTOPES; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 1942501178     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2004.02.002     Document Type: Article

References (20)

1. Alvarez-Diez T.M., deKemp R., Beanlands R., Vincent J. Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging in patients using positron emission tomograpy. Appl. Radiat. Isot. 50:1999;1015-1023
2. Bailey D.L., Young H., Bloomfield P.M., Meikle S.R., Glass D., Myers M.J., Spinks T.J., Watson C.C., Luk P., Peters A.M., Jones T. ECAT ART - a continuously rotating PET camera. performance characteristics, initial clinical studies, and installation considerations in a nuclear medicine department Eur. J. Nucl. Med. 24(1):1997;6-15
3. Beauchesne L.M., Ruddy T.D., deKemp R.A., Aung M.T., Levesque N., Alvarez-Diez T., Vickers T.K., Aubrey B.A., Beanlands R.S.B. Reproducibility of myocardial perfusion measurements with rubidium-82 PET imaging. (abstract) Circulation. 98:1998;I-222
4. Bracco Diagnostics, 2000. CardioGen-82 (Rubidium Rb 82 Generator) Package Insert, Princeton, NJ.
5. Demer L.L., Gould K.L., Goldstein R.A., Kikeeide R.L., Mullani N.A., Smalling R.W., Nishikawa A., Merhige M.E. Assessment of coronary artery disease severity by positron emission tomography. Circulation. 79:1989;825-835
6. 82Rb PET J. Nucl. Med. 41:2000;1426-1435
7. 82Rb generator elution profiles A secondary approach to radioassay/dosimetry Appl. Radiat. Isot. 38:1987;233-239
8. 82Rb generator eluates Appl. Radiat. Isot. 38:1987;219-225
9. Go R.T., Marwick T.H., MacIntyre W.J., Saha G.B., Neumann D.R., Underwood D.A., Simpfendorfer C.C. A prospective comparison of rubidium-82 PET and thallium-201 SPECT myocardial perfusion imaging utilizing a single dipyridamole stress in the diagnosis of coronary artery disease. J. Nucl. Med. 31:1990;1899-1905
10. Goldstein R.A., Mullani N.A., Marani S.K., Fisher D.J., Gould K.L., O'Brien H.A. Jr. Myocardial perfusion with rubidium-82. II. Effects of metabolic and pharamacologic interventions. J. Nucl. Med. 24:1983;907-915
11. Gould K.L., Goldstein R.A., Mullani N.A. Economic analysis of clinical positron emission tomography of the heart with rubidium-82. J. Nucl. Med. 30:1989;707-717
12. 82Rb and wavelet-based noise reduction J. Nucl. Med. 42:2001;201-208
13. MacIntyre W.J., Go R.T., King J.L., Cook S.A., Neumann D.R., Saha G.B., Antar M.A. Clinical outcome of cardiac patients with negative thallium-201 SPECT and positive rubidium-82 PET myocardial perfusion imaging. J. Nucl. Med. 34:1993;400-404
14. Raylman R.R., Caraher J.M., Hutchins G.D. Sampling requirements for dynamic cardiac PET studies using image-derived input functions. J. Nucl. Med. 34:1993;440-447
15. Stewart R.E., Schwaiger M., Molina E., Popma J., Gacioch G.M., Kalus M., Squicciarini S., Al-Aouar Z.R., Schork A., Kuhl D.E. Comparison of rubidium-82 positron emission tomography and thallium-201 SPECT imaging for detection of coronary artery disease. Am. J. Cardiol. 67:1991;1303-1310
16. Tallet J., Eiesner R.L., Mansour C.S., Patterson R.E. Ability of PET Rb-82 myocardial perfusion imaging to predict death. (abstract) J. Nucl. Med. 44:2003;2P
17. Williams B.R., Mullani N.A., Jansen D.E., Anderson B.A. A retrospective study of the diagnostic accuracy of a community hospital-based PET center for the detection of coronary artery disease using rubidium-82. J. Nucl. Med. 35:1994;1586-1592
18. Yano Y., Budinger T.F., Chiang G., O'Brien H.A., Grant P.M. Evaluation and application of alumina-based Rb-82 generators charged with high levels of Sr-82/85. J. Nucl. Med. 20:1979;961-966
19. Yano Y., Cahoon J.L., Budinger T.F. A precision flow-controlled Rb-82 generator for bolus or constant-infusion studies of the heart and brain. J. Nucl. Med. 22:1981;1006-1010
20. Yoshida K., Mullani N., Gould K.L. Coronary flow and flow reserve by PET simplified for clinical applications using rubidium-82 or nitrogen-13-ammonia. J. Nucl. Med. 37:1996;1701-1712