Elevated Free Tear Lactoferrin Levels in Leprosy are Associated with Type 2 Reactions

Indian Journal of Ophthalmology

Volumn 52, Issue 1, 2004, Pages 51-56

  Daniel, Ebenezer ^a   Duriasamy, Muruganand ^a   Ebenezer, Gigi J ^a   Shobhana, J ^a   Job, Charles K ^a  

^a Schieffelin Leprosy Res/Train Ctr   (India)

Author keywords

Antibodies to tear lactoferrin; Leprosy; Tear lactoferrin levels; Type 2 reaction

Indexed keywords

LACTOFERRIN; TEAR PROTEIN;

ADULT; AGE; AGED; ANTIBODY DETECTION; ARTICLE; CATARACT; CHI SQUARE DISTRIBUTION; CONTROLLED STUDY; CORNEA OPACITY; CORRELATION ANALYSIS; DEMOGRAPHY; DISEASE ASSOCIATION; ECTROPION; ENTROPION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENDER; HUMAN; HYPERSENSITIVITY REACTION; IMMUNOBLOTTING; IRIDOCYCLITIS; LACRIMAL FLUID; LAGOPHTHALMOS; LEPROSY; LIMB DEFORMITY; MALE; MULTIPLE REGRESSION; MUSCLE WEAKNESS; ORBICULARIS OCULI MUSCLE; PHOTOSTIMULATION; PROTEIN BLOOD LEVEL; REGRESSION ANALYSIS; STATISTICAL SIGNIFICANCE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; CASE-CONTROL STUDIES; FEMALE; HUMANS; LACTOFERRIN; LEPROSY, LEPROMATOUS; LINEAR MODELS; MALE; MIDDLE AGED; SEX DISTRIBUTION; TEARS;

EID: 1942467048     PISSN: 03014738     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Weinberg ED.Human lactoferrin: A novel therapeutic with broad spectrum potential. J Pharm Pharmacol 2001;53:1303-10.
2. Vorland LH, Ulvatne H, Andersen J, Haukland HH, Rekdal O, Svendsen JS and Gutteberg TJ. Antibacterial effects of lactoferricin B. Scand J Infect Dis. 1999;31:179-84.
3. Arnold RR, Brewer M and Gauthier JJ. Bactericidal activity of human lactoferrin: Sensitivity of a variety of micro-organisms Infect Immun 1980;28:893-98.
4. Britigan BE, Serody JS, Cohen MS. The role of lactoferrin as an anti-inflammatory molecule. Adv Exp Med Biol. 1994;357:143-56.
5. Lonnerdal B, Iyer S. Lactoferrin. Molecular structure and biological function. Annu Rev Nutr. 1995;15:93-110.
6. Jensen OL, Gluud BS, Birgens HS. The concentration of lactoferrin in tears of normals and of diabetics. Eur J Ophthalmol 2000;10:11-14.
7. Comerie-Smith SE, Nunez J, Hosmer M, Farris RL. Tear lactoferrin levels and ocular bacterial flora in HIV positive patients. Adv Exp Med Biol 1994;350:339-44.
8. Abe T, Nakajima A, Matsunaga M, Sakuragi S, Komatsu M. Decreased tear lactoferrin concentration in patients with chronic hepatitis C. Br J Ophthalmol 1999;83:684-87.
9. Kiratli H, Irkec M, Orhan M. Tear lactoferrin levels in chronic meibomitis associated with acne rosacea. Eur J Ophthalmol 2000;10:11-14.
10. Velasco Cabrera MJ, Garcia Sanchez J, Bermudez Rodriguez FJ. Lactoferrin in tears in contact lens wearers. CLAO J 1997;23:127-29.
11. Parkash O, Girdhar BK and Sengupta U. Serum lactoferrin in lepromatous leprosy patients Lepr Rev 1993;64:295-301.
12. Esaguy N, Aguas AP, Embden JDA, Silva MT. Mycobacteria and human auto-immune disease: Direct evidence of cross-reactivity between human lactoferrin and the 65-kilodalton protein of tubercle and leprosy bacilli. Infect Immun 1991;59:1117-25.
13. Ridley DS and Jopling WH. Classification of leprosy according to immunity: A five-group system. Int J Lepr 1966;34;255-73.
14. WHO Expert Committee on Leprosy. Geneva: World Health Organisation Tech Rep Ser 1988;768;1-51.
15. WHO Study Group. Chemotherapy of leprosy for control programs. Geneva: World Health Organization Tech Rep Ser 1982;675:21-26.
16. Kijlstra A, Jeurissen SHM, Koning KM. Lactoferrin levels in normal human tears. Br J Ophthalmol 1983;67:199-202.
17. Locht H, Skogh T, Kihlstrom E. Antilactoferrin antibodies and other types of anti-neutrophil cytoplasmic antibodies (ANCA) in reactive arthritis and ankylosing spondilytis. Clin Exp Immunol 1999;117:568-73.
18. Ballow M, Donshik PC, Rapacz P, Samartino L. Tear lactoferrin levels in patients with external inflammatory ocular disease. Invest Ophthalmol Vis Sci 1987;28:543-45.
19. Fullard RJ, Tucker DL. Changes in human tear protein levels with progressively increasing stimulus. Invest Ophthalmol Vis Sci 1991;32:2290-301.
20. Malmquist J, Thovell JI, Wollheim FA. Lactoferrin and lysozyme in arthritic exudates Acta Med Scand 1977;202:313-18.
21. McCollum CJ, Foulks GN, Bodner B, Shepard J, Daniels K, Gross V, Kelly L, Cavanagh HD. Rapid assay of lactoferrin in keratoconjunctivitis sicca. Cornea 1994 ;13:505-508.
22. Kumar R, Parmar IP, Chhillar N, Lal H. Tear lactoferrin concentration during postoperative ocular inflammation in cataract surgery. Acta Ophthalmol Scand 1997;75:142-44.
23. Leveugle B, Spik G, Perl DP, Bouras C, Fillit HM, Hof PR. The iron-binding protein lactotransferrin is present in pathologic lesions in a variety of neurodegenerative disorders: A comparative immunohistochemical analysis. Brain Res 1994;650:20-31.