pH-Dependent Geometric Isomerization of Roxithromycin in Simulated Gastrointestinal Fluids and in Rats

Journal of Pharmaceutical Sciences

Volumn 93, Issue 5, 2004, Pages 1300-1309

  Zhang, Shuqiu ^a   Xing, Jie ^a   Zhong, Dafang ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Degradation; Geometric isomerization; Liquid chromatography; Mass spectrometry; Metabolism; Roxithromycin

Indexed keywords

ROXITHROMYCIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG TRANSFORMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE FLUID; ISOMERIZATION; MALE; MASS SPECTROMETRY; NONHUMAN; PH; RAT; REACTION ANALYSIS; STOMACH JUICE;

EID: 1942466469     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20023     Document Type: Article

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