Expression of adrenomedullin in hypoxic and ischemic rat kidneys and human kidneys with arterial stenosis

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 286, Issue 5 55-5, 2004, Pages

  Sandner, Peter ^a   Hofbauer, Karl Heinz ^b   Tinel, Hanna ^a   Kurtz, Armin ^b   Thiesson, Helle C ^c   Ottosen, Peter D ^d   Walter, Steen ^d   Skøtt, Ole ^c   Jensen, Boye L ^c  

^a BAYER AG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Anemia; Hypertension; Infarct; Oxygen

Indexed keywords

ADRENOMEDULLIN; CARBON MONOXIDE;

ADULT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CASE REPORT; CELL CULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMATOCRIT; HENLE LOOP; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; KIDNEY ARTERY STENOSIS; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; KIDNEY DISTAL TUBULE; KIDNEY INFARCTION; KIDNEY ISCHEMIA; KIDNEY MEDULLA; KIDNEY PAPILLA; KIDNEY PERFUSION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM; SPECIES COMPARISON; UROTHELIUM;

ADRENOMEDULLIN; ANEMIA; ANIMALS; ANOXIA; CELLS, CULTURED; GENE EXPRESSION; HUMANS; HYPERTENSION, RENAL; IMMUNOHISTOCHEMISTRY; ISCHEMIA; KIDNEY; MALE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RENAL ARTERY OBSTRUCTION; RNA, MESSENGER;

EID: 1942454906     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00274.2003     Document Type: Article

References (38)

1. 2+-channel is localized to distal nephron segments and collecting ducts of the rat kidney. Am J Physiol Renal Physiol 279: F997-F1005, 2000.
2. Asada Y, Hara S, Marutsuka K, Kitamura K, Tsuji T, Sakata J, Sato Y, Kisanuki A, Eto T, and Sumiyoshi A. Novel distribution of adrenomedullin-immunoreactive cells in human tissues. Histochem Cell Biol 112: 185-191, 1999.
3. Chomczynski P and Sacchi N. Single-step method of RNA isolation by acid guanidinium-thiocyanate-phenol-chlororform extraction. Anal Biochem 162: 156-159, 1987.
4. Dobrzynski E, Wang C, Chao J, and Chao L. Adrenomedullin gene delivery attenuates hypertension, cardiac remodeling, and renal injury in deoxycorticosterone acetate-salt hypertensive rats. Hypertension 36: 995-1001, 2000.
5. Ebara T, Miura K, Okumura M, Matsuura T, Kim S, Yukimura T, and Iwao H. Effect of adrenomedullin on renal hemodynamics and functions in dogs. Eur J Pharmacol 263: 69-73, 1994.
6. Epstein FH. Oxygen and renal metabolism. Kidney Int 51: 381-385, 1997.
7. Gess B, Schricker K, Pfeifer M, and Kurtz A. Acute hypoxia upregulates NOS gene expression in rats. Am J Physiol Regul Integr Comp Physiol 273: R905-R910, 1997.
8. Harris RC and Breyer MD. Physiological regulation of cyclooxygenase-2 in the kidney. Am J Physiol Renal Physiol 281: F1-F11, 2001.
9. He H, Bessho H, Fujisawa Y, Horiuchi K, Tomohiso A, Kita T, Aki Y, Kimura S, Tamaki T, and Abe Y. Effects of a synthetic rat adrenomedullin on regional hemodynamics in rats. Eur J Pharmacol 273: 209-214, 1995.
10. Hofbauer KH, Jensen BL, Kurtz A, and Sandner P. Tissue hypoxygenation activates the adrenomedullin system in vivo. Am J Physiol Regul Integr Comp Physiol 278: R513-R519, 2000.
11. Hong H, Bessho H, Fujisawa Y, Horiuchi K, Tomohiro A, Kita T, Aki Y, Kimura S, Tamaki T, and Abe Y. Effects of a synthetic rat adrenomedullin on regional hemodynamics in rats. Eur J Pharmacol 273: 209-214, 1995.
12. Ichiki Y, Kitamura K, Kangawa K, Kawamoto M, Matsuo H, and Eto T. Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett 338: 6-10, 1994.
13. Jensen BL, Kramer BK, and Kurtz A. Adrenomedullin stimulates renin release and renin mRNA in mouse juxtaglomerular granular cells. Hypertension 29: 1148-1155, 1997.
14. Jensen BL, Gambaryan S, Schmaus E, and Kurtz A. Effects of dietary salt on adrenomedullin and its receptor mRNAs in rat kidney. Am J Physiol Renal Physiol 275: F55-F61, 1998.
15. Jougasaki M, Wie CM, Aarhus LL, Heublein DM, Sandberg SM, and Burnett JC. Renal localization and actions of adrenomedullin: a natriuretic peptide. Am J Physiol Renal Fluid Electrolyte Physiol 268: F657-F663, 1995.
16. Kato H, Shichiri M, Marumo F, and Hirata Y. Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells. Endocrinology 138: 2615-2620, 1997.
17. Kato J, Kitamura K, Matsui E, Tanaka M, Ishizaka Y, Kita T, Kangawa K, and Eto T. Plasma adrenomedullin and natriuretic peptides in patients with essential or malignant hypertension. Hypertens Res 22: 61-65.
18. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, and Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 192: 553-560, 1993.
19. Kitamura K, Sakata J, Kangawa K, Kojima M, Matsuo H, and Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem Biophys Res Commun 194: 720-725, 1993.
20. Majid DSA, Kadowitz PJ, Coy DH, and Navar LG. Renal responses to intra-arterial aministration of adrenomedullin in dogs. Am J Physiol Renal Fluid Electrolyte Physiol 270: F200-F205, 1996.
21. Mori Y, Nishikimi T, Kobayashi N, Ono H, Kangawa K, and Matsuoka H. Long-term adrenomedullin infusion improves survival in malignant hypertensive rats. Hypertension 40: 107-113, 2002.
22. Nagata D, Hirata Y, Suzuki E, Kakoki M, Hayakawa H, Goto A, Ishimitsu T, Minamino N, Ono Y, Kangawa K, Matsuo H, and Omata M. Hypoxia-induced adrenomedullin production in the kidney. Kidney Int 55: 1259-1267, 1999.
23. Nakayama M, Takahashi K, Murakami O, Shirato K, and Shibahara S. Induction of Adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells. Biochem Biophys Res Commun 243: 514-517, 1998.
24. Nguyen SV and Claycomb WC. Hypoxia regulates the expression of the adrenomedullin and HIF-1 genes in cultured HL-1 cardiomyocytes. Biochem Biophys Res Commun 265: 382-386, 1999.
25. Nishimatsu H, Hirata Y, Shindo T, Kurihara H, Kakoki M, Nagata D, Hayakawa H, Satonaka H, Sata M, Tojo A, Suzuki E, Kangawa K, Matsuo H, Kitamura K, and Nagai R. Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury. Circ Res 90: 657-663, 2002.
26. Nishiyama A, Mayatake A, Aki Y, Fukui T, Rahman M, Kimura S, and Abe Y. Adenosine A(1) receptor antagonist KW-3902 prevents hypoxia-induced renal vasoconstriction. J Pharmacol Exp Ther 291: 988-993, 1999.
27. Nishikimi T, Yoshihara F, Kanazawa A, Okano I, Horio T, Nagaya N, Yutani C, Matsuo H, Matsuoka H, and Kangawa K. Role of incresed circulating and renal adrenomedullin in rats with malignant hypertension. Am J Physiol Regul Integr Comp Physiol 281: R2079-R2087, 2001.
28. Øie E, Vinge LE, Yndestad A, Sandberg C, Grøgaard HK, and Attramadal H. Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats. Circulation 101: 415-422, 2000.
29. Pallone TL, Silldorf EP, and Turner MR. Intrarenal blood flow; microvascular anatomy and the regulation of medullary perfusion. Clin Exp Pharmacol Physiol 25: 383-392, 1998.
30. Rosenberger C, Mandiota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, and Eckardt KU. Expression of hypoxia-inducible factor 1α and -2α in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13: 1721-1732, 2002.
31. Sakata J, Shimokubo T, Kitamura K, Nakamura S, Kangawa K, Matsuo H, and Eto T. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. Biochem Biophys Res Commun 195: 921-927, 1993.
32. Sakata J, Shimokubo T, Kitamura K, Nishizono M, Ichiki Y, Kangawa K, Matsuo H, and Eto T. Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma. FEBS Lett 352: 105-108, 1994.
33. Seguchi H, Nishimura J, Kobayashi S, Kumazawa J, and Kanaide H. Autocrine regulation of the renal arterial tone by adrenomedullin. Biochem Biophys Res Commun 215: 619-625, 1995.
34. Stokes JB, Grupp C, and Kinne RKH. Purification of rat papillary collecting duct cells: functional and metabolic assessment. Am J Physiol Renal Fluid Electrolyte Physiol 253: F251-F262, 1987.
35. 2+ influx during regulatory volume decrease in IMCD cells. Am J Physiol Renal Fluid Electrolyte Physiol 267: F130-F138, 1994.
36. Wang X, Yue TL, Barone FC, White RF, Clarke RK, Willette RN, Sulpizio AC, Aiyar NV, Ruffolo RR Jr, and Feuerstein GZ. Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage. Proc Natl Acad Sci USA 92: 11480-11484, 1995.
37. Wang C, Dobrzynski E, Chao J, and Chao L. Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats. Am J Physiol Renal Physiol 280: F964-F971, 2001.
38. Zou AP, Yang ZZ, Li PL, and Cowley AW Jr. Oxygen-dependent expression of hypoxia-inducible factor-1α in renal medullary cells of rats. Physiol Genomics 6: 159-168, 2001.