Suppressor of sable, a Putative RNA-Processing Protein, Functions at the Level of Transcription

Molecular and Cellular Biology

Volumn 24, Issue 9, 2004, Pages 3734-3746

  Kuan, Yung Shu ^a,b   Brewer Jensen, Paul ^a   Searles, Lillie L ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b GEOPHYSICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GENE PRODUCT; PROTEIN; SABLE PROTEIN; UNCLASSIFIED DRUG;

ALLELISM; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE; GENE INSERTION; GENE OVEREXPRESSION; GENE REPRESSION; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN MOTIF; RNA PROCESSING; RNA TRANSCRIPTION; STRUCTURE ACTIVITY RELATION; SU GENE; TRANSCRIPTION REGULATION; TRANSGENE; TRANSPOSON; YEAST;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CHROMOSOMES; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; HELA CELLS; HISTONE DEACETYLASES; HUMANS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA; RNA PRECURSORS; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC; TRANSGENES; YEASTS;

DROSOPHILA MELANOGASTER; INSERTION SEQUENCES; MARTES ZIBELLINA; MELANOGASTER; TRANSPOSONS;

EID: 1942453899     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.9.3734-3746.2004     Document Type: Article

References (42)

1. Aapola, U., I. Liiv, and P. Peterson. 2002. Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. Nucleic Acids Res. 30:3602-3608.
2. Ashburner, M. 1989. Drosophila: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
3. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1995. Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N.Y.
4. Bai, W. 2000. Immunofluorescence analysis of suppressor of sable su(s) protein localization on larval salivary gland polytene chromosomes of Drosophila melanogaster. Ph.D. thesis. Department of Biology, University of North Carolina, Chapel Hill.
5. Barabino, S. M., W. Hubner, A. Jenny, L. Minvielle-Sebastia, and W. Keller. 1997. The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins. Genes Dev. 11:1703-1716.
6. Batchelder, C., M. A. Dunn, B. Choy, Y. Suh, C. Cassie, E. Y. Shim, T. H. Shin, C. Mello, G. Seydoux, and T. K. Blackwell. 1999. Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1. Genes Dev. 13:202-212.
7. Bentley, D. 1999. Coupling RNA polymerase II transcription with pre-mRNA processing. Curr. Opin. Cell Biol. 11:347-351.
8. Berger, S. L., W. D. Cress, A. Cress, S. J. Triezenberg, and L. Guarente. 1990. Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors. Cell 61:1199-1208.
9. Burnette, J. M., A. R. Hatton, and A. J. Lopez. 1999. trans-Acting factors required for inclusion of regulated exons in the Ultrabithorax mRNAs of Drosophila melanogaster. Genetics 151:1517-1529.
10. Carballo, E., W. S. Lai, and P. J. Blackshear. 1998. Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin. Science 281:1001-1005.
11. Chen, G., J. Fernandez, S. Mische, and A. J. Courey. 1999. A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development. Genes Dev. 13:2218-2230.
12. D'Avino, P. P., S. Crispi, L. C. Polito, and M. Furia. 1995. The role of the BR-C locus on the expression of genes located at the ecdysone-regulated 3C puff of Drosophila melanogaster. Mech. Dev. 49:161-171.
13. Deplus, R., C. Brenner, W. A. Burgers, P. Putmans, T. Kouzarides, Y. de Launoit, and F. Fuks. 2002. Dnmt3L is a transcriptional repressor that recruits histone deacetylase. Nucleic Acids Res. 30:3831-3838.
14. Fridell, R. A., A. M. Pret, and L. L. Searles. 1990. A retrotransposon 412 insertion within an exon of the Drosophila melanogaster vermilion gene is spliced from the precursor RNA. Genes Dev. 4:559-566.
15. Fridell, R. A., and L. L. Searles. 1994. Evidence for a role of the Drosophila melanogaster suppressor of sable gene in the pre-mRNA splicing pathway. Mol. Cell. Biol. 14:859-867.
16. Furger, A., J. M. O'Sullivan, A. Binnie, B. A. Lee, and N. J. Proudfoot. 2002. Promoter proximal splice sites enhance transcription. Genes Dev. 16:2792-2799.
17. Geyer, P. K., A. J. Chien, V. G. Corces, and M. M. Green. 1991. Mutations in the su(s) gene affect RNA processing in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 88:7116-7120.
18. Heinzel, T., R. M. Lavinsky, T. M. Mullen, M. Soderstrom, C. D. Laherty, J. Torchia, W. M. Yang, G. Brard, S. D. Ngo, J. R. Davie, E. Seto, R. N. Eisenman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1997. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387:43-48.
19. Higuchi, R. 1990. Recombinant PCR. Academic Press, Inc., San Diego, Calif.
20. Kim, N., J. Kim, D. Park, C. Rosen, D. Dorsett, and J. Yim. 1996. Structure and expression of wild-type and suppressible alleles of the Drosophila purple gene. Genetics 142:1157-1168.
21. Kirch, H. C., B. Putzer, G. Schwabe, H. K. Gnauck, and H. Schulte-Holthausen. 1993. Regulation of adenovirus 12 E1A transcription: E2F and ATF motifs in the E1A promoter bind nuclear protein complexes including E2F1, DP-1, cyclin A and/or RB and mediate transcriptional (auto)activation. Cell Mol. Biol. Res. 39:705-716.
22. Kwek, K. Y., S. Murphy, A. Furger, B. Thomas, W. O'Gorman, H. Kimura, N. J. Proudfoot, and A. Akoulitchev. 2002. U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nat. Struct. Biol. 9:800-805.
23. Lai, W. S., E. Carballo, J. M. Thorn, E. A. Kennington, and P. J. Blackshear. 2000. Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA. J. Biol. Chem. 275:17827-17837.
24. Lindsley, D. L., and G. G. Zimm. 1992. The genome of Drosophila melanogaster. Academic Press, Inc., San Diego, Calif.
25. Manoukian, A. S., H. M. Krause, and E. W. Larsen. 1992. Modifiers of bx1 alter the distribution of Ubx proteins in haltere imaginal discs of Drosophila. Dev. Biol. 151:611-616.
26. Mason, P. B., Jr., and J. T. Lis. 1997. Cooperative and competitive protein interactions at the hsp70 promoter. J. Biol. Chem. 272:33227-33233.
27. Mello, C. C., C. Schubert, B. Draper, W. Zhang, R. Lobel, and J. R. Priess. 1996. The PIE-1 protein and germline specification in Caenorhabditis elegans embryos. Nature 382:710-712.
28. Murray, M. V., M. A. Turnage, K. J. Williamson, W. R. Steinhauer, and L. L. Searles. 1997. The Drosophila suppressor of sable protein binds to RNA and associates with a subset of polytene chromosome bands. Mol. Cell. Biol. 17:2291-2300.
29. Nan, X., H. H. Ng, C. A. Johnson, C. D. Laherty, B. M. Turner, R. N. Eisenman, and A. Bird. 1998. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393:386-389.
30. Nguyen, V. T., T. Kiss, A. A. Michels, and O. Bensaude. 2001. 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes. Nature 414:322-325.
31. Orphanides, G., and D. Reinberg. 2002. A unified theory of gene expression. Cell 108:439-451.
32. Proudfoot, N. J., A. Furger, and M. J. Dye. 2002. Integrating mRNA processing with transcription. Cell 108:501-512.
33. Reese, K. J., M. A. Dunn, J. A. Waddle, and G. Seydoux. 2000. Asymmetric segregation of PIE-1 in Caenorhabditis elegans is mediated by two complementary mechanisms that act through separate PIE-1 protein domains. Mol. Cell 6:445-455.
34. Rubin, G. M., and A. C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218:348-353.
35. Rutledge, B. J., M. A. Mortin, E. Schwarz, D. Thierry-Mieg, and M. Meselson. 1988. Genetic interactions of modifier genes and modifiable alleles in Drosophila melanogaster. Genetics 119:391-397.
36. Searles, L. L., and R. A. Voelker. 1986. Molecular characterization of the Drosophila vermilion locus and its suppressible alleles. Proc. Natl. Acad Sci. USA 83:404-408.
37. Turnage, M. A. 1998. In vitro and in vivo analysis of the suppressor of sable [su(s)] gene of Drosophila melanogaster. Ph.D. thesis. Department of Biology, University of North Carolina, Chapel Hill.
38. Turnage, M. A., P. Brewer-Jensen, W. L. Bai, and L. L. Searles. 2000. Arginine-rich regions mediate the RNA binding and regulatory activities of the protein encoded by the Drosophila melanogaster suppressor of sable gene. Mol. Cell. Biol. 20:8198-8208.
39. Voelker, R. A., W. Gibson, J. P. Graves, J. F. Sterling, and M. T. Eisenberg. 1991. The Drosophila suppressor of sable gene encodes a polypeptide with regions similar to those of RNA-binding proteins. Mol. Cell. Biol. 11:894-905.
40. Xiao, H., J. D. Friesen, and J. T. Lis. 1994. A highly conserved domain of RNA polymerase II shares a functional element with acidic activation domains of upstream transcription factors. Mol. Cell. Biol. 14:7507-7516.
41. Xiao, H., A. Pearson, B. Coulombe, R. Truant, S. Zhang, J. L. Regier, S. J. Triezenberg, D. Reinberg, O. Flores, C. J. Ingles, et al. 1994. Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53. Mol. Cell. Biol. 14:7013-7024.
42. Yang, Z., Q. Zhu, K. Luo, and Q. Zhou. 2001. The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature 414:317-322.