An Economic Evaluation of Intermittent Cyclosporin A Therapy versus UVAB Phototherapy in the Treatment of Patients with Severe Atopic Dermatitis

Acta Dermato-Venereologica

Volumn 84, Issue 2, 2004, Pages 138-141

  Salo, Heini ^a,c   Pekurinen, Markku ^a   Granlund, Håkan ^a   Nuutinen, Marja ^b   Erkko, Pekka ^a   Reitamo, Sakari ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b Novartis Finland Ltd   (Finland)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Atopic dermatitis; Cost effectiveness; Direct costs; Indirect costs; Patient's perspective

Indexed keywords

CORTICOSTEROID; CYCLOSPORIN A; EMOLLIENT AGENT; IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; ATOPIC DERMATITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; DRUG INTERMITTENT THERAPY; ECONOMIC EVALUATION; EVALUATION; FEMALE; FINLAND; HEALTH CARE COST; HEALTH CARE UTILIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; OPEN STUDY; OUTCOMES RESEARCH; PHOTOTHERAPY; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; REMISSION; TREATMENT FAILURE; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION;

EID: 1942443898     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Granlund H, Erkko P, Remitz A, Langeland T, Helsing P, Nuutinen M, et al. Comparison of cyclosporin and UVAB phototherapy for intermittent one-year treatment of atopic dermatitis. Acta Derm Venereol 2001; 81: 22-27.
2. Berth-Jones J, Takwale A, Tan E, Barclay G, Agarwal S, Ahmed I, et al. Azathioprine in severe adult atopic dermatitis: a double-blind, placebo-controlled, crossover trial. Br J Dermatol 2002; 147: 324-30.
3. Borel JF, Feurer C, Gubler HU, Stähelin H. Biological effects of cyclosporin A: a new antilymphocytic agent. Agents Actions 1976; 6: 468-475.
4. Ellis CN, Gorsulowsky DC, Hamilton TA, Billings JK, Brown MD, Headington JT, et al. Cyclosporine improves psoriasis in a double-blind study. JAMA 1986; 256: 3110-3116.
5. Granlund H, Camp RDR, Reitamo S. Cyclosporin A in the treatment of atopic dermatitis. J Dermatol Treat 1993; 4: S15-S17, 3.
6. Sowden JM, Berth-Jones J, Ross JS, Motley RJ, Marks R, Finlay AY, et al. Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis. Lancet 1991; 338: 137-140.
7. van Joost T, Heule F, Korstanje M, van den Broek MJ, Stenveld HJ, van Vloten WA. Cyclosporin in atopic dermatitis: a multicentre placebo-controlled study. Br J Dermatol 1994; 130: 634-640.
8. Granlund H, Erkko P, Sinisalo M, Reitamo S. Cyclosporin in atopic dermatitis: time to relapse and effect of intermittent therapy. Br J Dermatol 1995; 132: 106-112.
9. Zonneveld IM, De Rie MA, Beljaards RC, Van Der Rhee HJ, Wuite J, Zeegelaar J, et al. The long-term safety and efficacy of cyclosporin in severe refractory atopic dermatitis: a comparison of two dosage regimens. Br J Dermatol 1996; 135 Suppl. 48: 15-20.
10. Berth-Jones J, Graham-Brown RA, Marks R, Camp RD, English JS, Freeman K, et al. Long-term efficacy and safety of cyclosporin in severe adult atopic dermatitis. Br J Dermatol 1997; 136: 76-81.
11. Drummond MF, O'Brien B, Stoddard GL, Torrance GW Methods for the economic evaluation of health care programmes, 2nd ed. Oxford Medical Publications, 1997.
12. Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology 1993; 186: 23-31.
13. Salek MS, Finlay AY, Luscombe DK, Allen BR, Berth-Jones J, Camp RD, et al. Cyclosporin greatly improves the quality of life of adults with severe atopic dermatitis. A randomized, double-blind, placebo-controlled trial. Br J Dermatol 1993; 129: 422-430.
14. Finlay AY, Khan GK. Dermatology life quality index (DLQI) - a simple practical measure for routine clinical use. Clin Exp Dermatol 1994; 19: 210-216.
15. Lapidus CS, Schwarz DF, Honig PJ. Atopic dermatitis in children: who cares? Who pays? J Am Acad Dermatol 1993; 28: 699-703.
16. Rook A, Savin JA, Wilkinson D. The prevalence, incidence and ecology of diseases of the skin. In: Rook A, Wilkinson DS, Ebling FJG et al. eds. Textbook of dermatology, 4th ed., vol. 1. Oxford: Blackwell, 1986: 40.