Three new cyclostellettamines, which inhibit histone deacetylase, from a marine sponge of the genus Xestospongia

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 10, 2004, Pages 2617-2620

  Oku, Naoya ^a   Nagai, Koji ^b   Shindoh, Nobuaki ^b   Terada, Yoh ^b   Van Soest, Rob W M ^c   Matsunaga, Shigeki ^a   Fusetani, Nobuhiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Cyclic pyridine; Histone deacetylase; Inhibitor; Marine sponge

Indexed keywords

CYCLOSTELLETTAMINE A; CYCLOSTELLETTAMINE G; DEHYDROCYCLOSTELLETTAMINE D; DEHYDROCYCLOSTELLETTAMINE E; HISTONE DEACETYLASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; MOUSE; NONHUMAN; RAT;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; PYRIDINIUM COMPOUNDS; RATS; XESTOSPONGIA;

XESTOSPONGIA;

EID: 1942438219     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.062     Document Type: Article

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