Studying unidentified impurities in drug substances by the application of multivariate (principal component and cluster) analysis

Quality Engineering

Volumn 16, Issue 3, 2004, Pages 475-485

  Gonzales de la Parra, Mario ^a   Rodriguez Loaiza, Pilar ^a   Namur, Salvador ^b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b Fundacion Liomont AC   (Mexico)

Author keywords

Chemical and pharmaceutical processes; Cluster analysis; Drug substances; Impurity profile; Principal component analysis

Indexed keywords

CHEMICAL PLANTS; CORRELATION METHODS; DRUG PRODUCTS; EIGENVALUES AND EIGENFUNCTIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMPURITIES; MATRIX ALGEBRA; STRUCTURE (COMPOSITION);

CLUSTER ANALYSIS; CORRELATION MATRIX; DRUG SUBSTANCES; PRODUCT COMPONENT;

PRINCIPAL COMPONENT ANALYSIS;

EID: 1942436718     PISSN: 08982112     EISSN: None     Source Type: Journal    
DOI: 10.1081/QEN-120027948     Document Type: Article

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