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Volumn 166, Issue 3, 2004, Pages 1141-1154

Neurological Proteins Are Not Enriched for Repetitive Sequences

Author keywords

[No Author keywords available]

Indexed keywords

NERVE PROTEIN; POLYGLUTAMINE; POLYMER; SERINE;

EID: 1942421831     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.166.3.1141     Document Type: Article
Times cited : (12)

References (48)
  • 1
    • 0036080338 scopus 로고    scopus 로고
    • Detecting cryptically simple protein sequences using the SIMPLE algorithm
    • ALBA, M. M., R. A. LASKOWSKI and J. M. HANCOCK, 2002 Detecting cryptically simple protein sequences using the SIMPLE algorithm. Bioinformatics 18: 672-678.
    • (2002) Bioinformatics , vol.18 , pp. 672-678
    • Alba, M.M.1    Laskowski, R.A.2    Hancock, J.M.3
  • 2
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • ALTSCHUL, S. F., T. L. MADDEN, A. A. SCHAFFER, J. ZHANG, Z. ZHANG et al., 1997 Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25: 3389-3402.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3    Zhang, J.4    Zhang, Z.5
  • 3
    • 0028017992 scopus 로고
    • Identification and characterization of the gene causing type 1 spinocerebellar ataxia
    • BANFI, S., A. SERVADIO, M. Y. CHUNG, T. J. KWIATKOWSKI JR., A. E. MCCALL et al., 1994 Identification and characterization of the gene causing type 1 spinocerebellar ataxia. Nat. Genet. 7: 513-520.
    • (1994) Nat. Genet. , vol.7 , pp. 513-520
    • Banfi, S.1    Servadio, A.2    Chung, M.Y.3    Kwiatkowski Jr., T.J.4    Mccall, A.E.5
  • 4
    • 0028169738 scopus 로고
    • The Haw River syndrome: Dentatorubropallidoluysian atrophy (DRPLA) in an African-American family
    • BURKE, J. R., M. S. WINGFIELD, K. E. LEWIS, A. D. ROSES, J. E. LEE et al., 1994 The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family. Nat. Genet. 7: 521-524.
    • (1994) Nat. Genet. , vol.7 , pp. 521-524
    • Burke, J.R.1    Wingfield, M.S.2    Lewis, K.E.3    Roses, A.D.4    Lee, J.E.5
  • 5
    • 10544228522 scopus 로고    scopus 로고
    • Transglutaminase activity is related to CAG repeat length in patients with Huntington's disease
    • CARIELLO, L., T. DE CRISTOFARO, L. ZANETTI, T. CUOMO, L. DI MAIO et al., 1996 Transglutaminase activity is related to CAG repeat length in patients with Huntington's disease. Hum. Genet. 98: 633-635.
    • (1996) Hum. Genet. , vol.98 , pp. 633-635
    • Cariello, L.1    De Cristofaro, T.2    Zanetti, L.3    Cuomo, T.4    Di Maio, L.5
  • 6
    • 0032717267 scopus 로고    scopus 로고
    • Microsatellite and trinucleotide-repeat evolution: Evidence for mutational bias and different rates of evolution in different lineages
    • COOPER, G., N. J. BURROUGHS, D. A. RAND, D. C. RUBINSZTEIN and W. AMOS, 1999 Microsatellite and trinucleotide-repeat evolution: evidence for mutational bias and different rates of evolution in different lineages. Proc. Natl. Acad. Sci. USA 96: 11916-11921.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11916-11921
    • Cooper, G.1    Burroughs, N.J.2    Rand, D.A.3    Rubinsztein, D.C.4    Amos, W.5
  • 7
    • 16944364511 scopus 로고    scopus 로고
    • Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion
    • DAVID, G., N. ABBAS, G. STEVANIN, A. DURR, G. YVERT et al., 1997 Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nat. Genet. 17: 65-70.
    • (1997) Nat. Genet. , vol.17 , pp. 65-70
    • David, G.1    Abbas, N.2    Stevanin, G.3    Durr, A.4    Yvert, G.5
  • 9
    • 0027240431 scopus 로고
    • Trinucleotide repeat length instability and age of onset in Huntington's disease
    • DUYAO, M., C. AMBROSE, R. MYERS, A. NOVELLETTO, F. PERSICHETTI et al., 1993 Trinucleotide repeat length instability and age of onset in Huntington's disease. Nat. Genet. 4: 387-392.
    • (1993) Nat. Genet. , vol.4 , pp. 387-392
    • Duyao, M.1    Ambrose, C.2    Myers, R.3    Novelletto, A.4    Persichetti, F.5
  • 10
    • 0033027083 scopus 로고    scopus 로고
    • Simple sequence is abundant in eukaryotic proteins
    • GOLDING, G. B., 1999 Simple sequence is abundant in eukaryotic proteins. Protein Sci. 8: 1358-1361.
    • (1999) Protein Sci. , vol.8 , pp. 1358-1361
    • Golding, G.B.1
  • 11
    • 0028325481 scopus 로고
    • Codon reiteration and the evolution of proteins
    • GREEN, H., and N. WANG, 1994 Codon reiteration and the evolution of proteins. Proc. Natl. Acad. Sci. USA 91: 4298-4302.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4298-4302
    • Green, H.1    Wang, N.2
  • 13
    • 0033845697 scopus 로고    scopus 로고
    • Evolution of simple sequence in proteins
    • HUNTLEY, M., and G. B. GOLDING, 2000 Evolution of simple sequence in proteins. J. Mol. Evol. 51: 131-140.
    • (2000) J. Mol. Evol. , vol.51 , pp. 131-140
    • Huntley, M.1    Golding, G.B.2
  • 14
    • 0036643433 scopus 로고    scopus 로고
    • Simple sequences are rare in the Protein Data Bank
    • HUNTLEY, M. A., and G. B. GOLDING, 2002 Simple sequences are rare in the Protein Data Bank. Proteins 48: 134-140.
    • (2002) Proteins , vol.48 , pp. 134-140
    • Huntley, M.A.1    Golding, G.B.2
  • 15
    • 0029983147 scopus 로고    scopus 로고
    • Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development
    • KARLIN, S., and C. BURGE, 1996 Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development. Proc. Natl. Acad. Sci. USA 93: 1560-1565.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1560-1565
    • Karlin, S.1    Burge, C.2
  • 17
    • 0028143527 scopus 로고
    • CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1
    • KAWAGUCHI, Y., T. OKAMOTO, M. TANIWAKI, M. AIZAWA, M. INOUE et al., 1994 CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1. Nat. Genet. 8: 221-228.
    • (1994) Nat. Genet. , vol.8 , pp. 221-228
    • Kawaguchi, Y.1    Okamoto, T.2    Taniwaki, M.3    Aizawa, M.4    Inoue, M.5
  • 18
    • 0028099274 scopus 로고
    • Trinucleotide repeat length and progression of illness in Huntington's disease
    • KIEBURTZ, K., M. MACDONALD, C. SHIH, A. FEIGIN, K. STEINBERG et al., 1994 Trinucleotide repeat length and progression of illness in Huntington's disease. J. Med. Genet. 31: 872-874.
    • (1994) J. Med. Genet. , vol.31 , pp. 872-874
    • Kieburtz, K.1    Macdonald, M.2    Shih, C.3    Feigin, A.4    Steinberg, K.5
  • 19
    • 0028216760 scopus 로고
    • Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA)
    • KOIDE, R., T. IKEUCHI, O. ONODERA, H. TANAKA, S. IGARASHI et al., 1994 Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA). Nat. Genet. 6: 9-13.
    • (1994) Nat. Genet. , vol.6 , pp. 9-13
    • Koide, R.1    Ikeuchi, T.2    Onodera, O.3    Tanaka, H.4    Igarashi, S.5
  • 20
    • 0001676653 scopus 로고
    • Synthetic polypeptides containing sidechain amide groups: Water insoluble polymers
    • KRULL, L., J. WALL, H. ZOBEL and R. DIMLER, 1965 Synthetic polypeptides containing sidechain amide groups: water insoluble polymers. Biochemistry 4: 626-632.
    • (1965) Biochemistry , vol.4 , pp. 626-632
    • Krull, L.1    Wall, J.2    Zobel, H.3    Dimler, R.4
  • 21
    • 0025800526 scopus 로고
    • Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
    • LA SPADA, A. R., E. M. WILSON, D. B. LUBAHN, A. E. HARDING and K. H. FISCHBECK, 1991 Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352: 77-79.
    • (1991) Nature , vol.352 , pp. 77-79
    • La Spada, A.R.1    Wilson, E.M.2    Lubahn, D.B.3    Harding, A.E.4    Fischbeck, K.H.5
  • 22
    • 0031576337 scopus 로고    scopus 로고
    • Glutamine, alanine or glycine repeats inserted into the loop of a protein have minimal effects on stability and folding rates
    • LADURNER, A. G., and A. R. FERSHT, 1997 Glutamine, alanine or glycine repeats inserted into the loop of a protein have minimal effects on stability and folding rates. J. Mol. Biol. 273: 330-337.
    • (1997) J. Mol. Biol. , vol.273 , pp. 330-337
    • Ladurner, A.G.1    Fersht, A.R.2
  • 23
    • 0027297703 scopus 로고
    • Novel triplet repeat containing genes in human brain: Cloning, expression, and length polymorphisms
    • LI, S. H., M. G. MCINNIS, R. L. MARGOLIS, S. E. ANTONARAKIS and C. A. ROSS, 1993 Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms. Genomics 16: 572-579.
    • (1993) Genomics , vol.16 , pp. 572-579
    • Li, S.H.1    Mcinnis, M.G.2    Margolis, R.L.3    Antonarakis, S.E.4    Ross, C.A.5
  • 25
    • 0033280242 scopus 로고    scopus 로고
    • Amino acid reiterations in yeast are overrepresented in particular classes of proteins and show evidence of a slippage-like mutational process
    • MAR ALBA, M., M. F. SANTIBANEZ-KOREF and J. M. HANCOCK, 1999 Amino acid reiterations in yeast are overrepresented in particular classes of proteins and show evidence of a slippage-like mutational process. J. Mol. Evol. 49: 789-797.
    • (1999) J. Mol. Evol. , vol.49 , pp. 789-797
    • Mar Alba, M.1    Santibanez-Koref, M.F.2    Hancock, J.M.3
  • 27
    • 0024396320 scopus 로고
    • Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
    • MITCHELL, P. J., and R. TJIAN, 1989 Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245: 371-378.
    • (1989) Science , vol.245 , pp. 371-378
    • Mitchell, P.J.1    Tjian, R.2
  • 28
    • 0028065674 scopus 로고
    • Adaptive evolution of highly mutable loci in pathogenic bacteria
    • MOXON, E. R., P. B. RAINEY, M. A. NOWAK and R. E. LENSKI, 1994 Adaptive evolution of highly mutable loci in pathogenic bacteria. Curr. Biol. 4: 24-33.
    • (1994) Curr. Biol. , vol.4 , pp. 24-33
    • Moxon, E.R.1    Rainey, P.B.2    Nowak, M.A.3    Lenski, R.E.4
  • 29
    • 0023984847 scopus 로고
    • Optimal alignments in linear-space
    • MYERS, E. W., and W. MILLER, 1988 Optimal alignments in linear-space. Comput. Appl. Biosci. 4: 11-17.
    • (1988) Comput. Appl. Biosci. , vol.4 , pp. 11-17
    • Myers, E.W.1    Miller, W.2
  • 30
    • 0028335386 scopus 로고
    • Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p
    • NAGAFUCHI, S., H. YANAGISAWA, K. SATO, T. SHIRAYAMA, E. OHSAKI et al., 1994 Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p. Nat. Genet. 6: 14-18.
    • (1994) Nat. Genet. , vol.6 , pp. 14-18
    • Nagafuchi, S.1    Yanagisawa, H.2    Sato, K.3    Shirayama, T.4    Ohsaki, E.5
  • 31
    • 0035393427 scopus 로고    scopus 로고
    • SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein
    • NAKAMURA, K., S. Y. JEONG, T. UCHIHARA, M. ANNO, K. NAGASHIMA et al., 2001 SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein. Hum. Mol. Genet. 10: 1441-1448.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1441-1448
    • Nakamura, K.1    Jeong, S.Y.2    Uchihara, T.3    Anno, M.4    Nagashima, K.5
  • 32
    • 0035849879 scopus 로고    scopus 로고
    • Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats
    • PERUTZ, M. F., and A. H. WINDLE, 2001 Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats. Nature 412: 143-144.
    • (2001) Nature , vol.412 , pp. 143-144
    • Perutz, M.F.1    Windle, A.H.2
  • 33
    • 0028283985 scopus 로고
    • Glutamine repeats as polar zippers: Their possible role in inherited neurodegenerative diseases
    • PERUTZ, M. F., T. JOHNSON, M. SUZUKI and J. T. FINCH, 1994 Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases. Proc. Natl. Acad. Sci. USA 91: 5355-5358.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5355-5358
    • Perutz, M.F.1    Johnson, T.2    Suzuki, M.3    Finch, J.T.4
  • 34
    • 0037117499 scopus 로고    scopus 로고
    • Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques
    • PERUTZ, M. F., B. J. POPE, D. OWEN, E. E. WANKER and E. SCHERZINGER, 2002 Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques. Proc. Natl. Acad. Sci. USA 99: 5596-5600.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5596-5600
    • Perutz, M.F.1    Pope, B.J.2    Owen, D.3    Wanker, E.E.4    Scherzinger, E.5
  • 35
    • 0030292488 scopus 로고    scopus 로고
    • Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2
    • PULST, S. M., A. NECHIPORUK, T. NECHIPORUK, S. GISPERT, X. N. CHEN et al., 1996 Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2. Nat. Genet. 14: 269-276.
    • (1996) Nat. Genet. , vol.14 , pp. 269-276
    • Pulst, S.M.1    Nechiporuk, A.2    Nechiporuk, T.3    Gispert, S.4    Chen, X.N.5
  • 36
    • 0033616581 scopus 로고    scopus 로고
    • Alanine is helix-stabilizing in both template-nucleated and standard peptide helices
    • ROHL, C. A., W. FIORI and R. L. BALDWIN, 1999 Alanine is helix-stabilizing in both template-nucleated and standard peptide helices. Proc. Natl. Acad. Sci. USA 96: 3682-3687.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3682-3687
    • Rohl, C.A.1    Fiori, W.2    Baldwin, R.L.3
  • 37
    • 0032726594 scopus 로고    scopus 로고
    • Folding minimal sequences: The lower bound for sequence complexity of globular proteins
    • ROMERO, P., Z. OBRADOVIC and A. K. DUNKER, 1999 Folding minimal sequences: the lower bound for sequence complexity of globular proteins. FEBS Lett. 462: 363-367.
    • (1999) FEBS Lett. , vol.462 , pp. 363-367
    • Romero, P.1    Obradovic, Z.2    Dunker, A.K.3
  • 39
    • 0033614763 scopus 로고    scopus 로고
    • Microsatellite and trinucleotide-repeat evolution: Evidence for mutational bias and different rates of evolution in different lineages
    • RUBINSZTEIN, D. C., B. AMOS and G. COOPER, 1999 Microsatellite and trinucleotide-repeat evolution: evidence for mutational bias and different rates of evolution in different lineages. Philos. Trans. R. Soc. Lond. B 354: 1095-1099.
    • (1999) Philos. Trans. R. Soc. Lond. B. , vol.354 , pp. 1095-1099
    • Rubinsztein, D.C.1    Amos, B.2    Cooper, G.3
  • 40
    • 0000361948 scopus 로고    scopus 로고
    • Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58
    • SAUNDERS, N. J., A. C. JEFFRIES, J. F. PEDEN, D. W. HOOD, H. TETTELIN et al., 2000 Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58. Mol. Microbiol. 37: 207-215.
    • (2000) Mol. Microbiol. , vol.37 , pp. 207-215
    • Saunders, N.J.1    Jeffries, A.C.2    Peden, J.F.3    Hood, D.W.4    Tettelin, H.5
  • 41
    • 0036220140 scopus 로고    scopus 로고
    • Trinucleotide repeats in 202 families with ataxia: A small expanded (CAG)n allele at the SCA17 locus
    • SILVEIRA, I., C. MIRANDA, L. GUIMARAES, M. C. MOREIRA, I. ALONSO et al., 2002 Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n allele at the SCA17 locus. Arch. Neurol. 59: 623-629.
    • (2002) Arch. Neurol. , vol.59 , pp. 623-629
    • Silveira, I.1    Miranda, C.2    Guimaraes, L.3    Moreira, M.C.4    Alonso, I.5
  • 42
    • 0027261537 scopus 로고
    • Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease
    • SNELL, R. G., J. C. MACMILLAN, J. P. CHEADLE, I. FENTON, L. P. LAZAROU et al., 1993 Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nat. Genet. 4: 393-397.
    • (1993) Nat. Genet. , vol.4 , pp. 393-397
    • Snell, R.G.1    Macmillan, J.C.2    Cheadle, J.P.3    Fenton, I.4    Lazarou, L.P.5
  • 43
    • 0022974221 scopus 로고
    • Opacity genes in Neisseria gonorrhoeae: Control of phase and antigenic variation
    • STERN, A., M. BROWN, P. NICKEL and T. F. MEYER, 1986 Opacity genes in Neisseria gonorrhoeae: control of phase and antigenic variation. Cell 47: 61-71.
    • (1986) Cell , vol.47 , pp. 61-71
    • Stern, A.1    Brown, M.2    Nickel, P.3    Meyer, T.F.4
  • 44
    • 0028970090 scopus 로고
    • Structure and function of transcriptional activation domains
    • TRIEZENBERG, S. J., 1995 Structure and function of transcriptional activation domains. Curr. Opin. Genet. Dev. 5: 190-196.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 190-196
    • Triezenberg, S.J.1
  • 45
    • 0021926007 scopus 로고
    • opa: A novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster
    • WHARTON, K. A., B. YEDVOBNICK, V. G. FINNERTY and S. ARTAVANIS-TSAKONAS, 1985 opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster. Cell 40: 55-62.
    • (1985) Cell , vol.40 , pp. 55-62
    • Wharton, K.A.1    Yedvobnick, B.2    Finnerty, V.G.3    Artavanis-Tsakonas, S.4
  • 46
    • 0001514262 scopus 로고
    • Statistics of local complexity in amino acid sequences and sequence databases
    • WOOTTON, J. C., and S. FEDERHEN, 1993 Statistics of local complexity in amino acid sequences and sequence databases. Comput. Chem. 17: 149-163.
    • (1993) Comput. Chem. , vol.17 , pp. 149-163
    • Wootton, J.C.1    Federhen, S.2
  • 47
    • 0034702086 scopus 로고    scopus 로고
    • Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine
    • YANAGISAWA, H., M. BUNDO, T. MIYASHITA, Y. OKAMURA-OHO, K. TADOKORO et al., 2000 Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine. Hum. Mol. Genet. 9: 1433-1442.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1433-1442
    • Yanagisawa, H.1    Bundo, M.2    Miyashita, T.3    Okamura-Oho, Y.4    Tadokoro, K.5
  • 48
    • 0031012399 scopus 로고    scopus 로고
    • Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel
    • ZHUCHENKO, O., J. BAILEY, P. BONNEN, T. ASHIZAWA, D. W. STOCKTON et al., 1997 Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel. Nat. Genet. 15: 62-69.
    • (1997) Nat. Genet. , vol.15 , pp. 62-69
    • Zhuchenko, O.1    Bailey, J.2    Bonnen, P.3    Ashizawa, T.4    Stockton, D.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.