Hexachlorobenzene, a dioxin-like compound, disrupts auditory function in rat

Hearing Research

Volumn 191, Issue 1-2, 2004, Pages 125-134

  Hadjab, Saida ^a   Maurel, Daniel ^a   Cazals, Yves ^a   Siaud, Philippe ^a  

^a INSERM   (France)

Author keywords

Cochlea; Hearing loss; Hexachlorobenzene; Ototoxicity; Rat; Thyroid hormone

Indexed keywords

DIOXIN; HEXACHLOROBENZENE; OLIVE OIL; THYROTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD; CELL LOSS; COCHLEA; COCHLEAR NERVE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; HAIR CELL; HEARING; HISTOLOGY; MALE; MEASUREMENT; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; RADIATION INJURY; RADIOIMMUNOASSAY; RAT; SCANNING ELECTRON MICROSCOPY; STEREOCILIUM; THYROIDECTOMY; THYROTROPIN BLOOD LEVEL;

ANIMALS; AUDITORY THRESHOLD; CASE-CONTROL STUDIES; COCHLEA; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNGICIDES, INDUSTRIAL; HAIR CELLS; HEARING LOSS; HEXACHLOROBENZENE; MALE; MICROSCOPY, ELECTRON, SCANNING; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; THYROID GLAND; THYROID HORMONES; THYROIDECTOMY;

EID: 1942421763     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.heares.2003.12.017     Document Type: Article

References (59)

1. Ahmad S., Chen S., Sun J., Lin X. Connexins 26 and 30 are co-assembled to form gap junctions in the cochlea of mice. Biochem. Biophys. Res. Commun. 307:2003;362-368.
2. Andrews J.E., Courtney K.D., Donaldson W.E. Impairment of calcium homeostasis by hexachlorobenzene (HCB) exposure in Fischer 344 rats. J. Toxicol. Environ. Health. 23:1988;311-320.
3. Arnold D.L., Moodie C.A., Collins B.T., Zawidzka Z.Z., Krewski D.R. Two-generation chronic toxicity study with hexachlorobenzene in the rat. IARC Sci. Publ. 1986;405-410.
4. Bleavins M.R., Aulerich R.J., Ringer R.K. Effects of chronic dietary hexachlorobenzene exposure on the reproductive performance and survivability of mink and European ferrets. Arch. Environ. Contam. Toxicol. 13:1984;357-365.
5. Burns J.E., Miller F.M. Hexachlorobenzene contamination: its effects in a Louisiana population. Arch. Environ. Health. 30:1975;44-48.
6. Byrne J.J., Carbone J.P., Hanson E.A. Hypothyroidism and abnormalities in the kinetics of thyroid hormone metabolism in rats treated chronically with polychlorinated biphenyl and polybrominated biphenyl. Endocrinology. 121:1987;520-527.
7. Campo P., Lataye R., Cossec B., Placidi V. Toluene-induced hearing loss: a mid-frequency location of the cochlear lesions. Neurotoxicol. Teratol. 19:1997;129-140.
8. Campo P., Loquet G., Blachere V., Roure M. Toluene and styrene intoxication route in the rat cochlea. Neurotoxicol. Teratol. 21:1999;427-434.
9. Cappaert N.L., Klis S.F., Muijser H., de Groot J.C., Kulig B.M., Smoorenburg G.F. The ototoxic effects of ethyl benzene in rats. Hear. Res. 137:1999;91-102.
10. Cappaert N.L., Klis S.F., Baretta A.B., Muijser H., Smoorenburg G.F. Ethyl benzene-induced ototoxicity in rats: a dose-dependent mid-frequency hearing loss. J. Assoc. Res. Otolaryngol. 1:2000;292-299.
11. Cazals Y., Huang Z.W. Average spectrum of cochlear activity: a possible synchronized firing, its olivo-cochlear feedback and alterations under anesthesia. Hear. Res. 101:1996;81-92.
12. Courtney K.D. Hexachlorobenzene (HCB): a review. Environ. Res. 20:1979;225-266.
13. ′,5-pentachlorobiphenyl (PCB 126) in rats Neurotoxicol. Teratol. 21:1999;299-301.
14. Crofton K.M., Lassiter T.L., Rebert C.S. Solvent-induced ototoxicity in rats: an atypical selective mid-frequency hearing deficit. Hear. Res. 80:1994;25-30.
15. Crofton K.M., Kodavanti P.R., Derr-Yellin E.C., Casey A.C., Kehn L.S. PCBs, thyroid hormones, and ototoxicity in rats: cross-fostering experiments demonstrate the impact of postnatal lactation exposure. Toxicol. Sci. 57:2000;131-140.
16. Crofton K.M., Ding D., Padich R., Taylor M., Henderson D. Hearing loss following exposure during development to polychlorinated biphenyls: a cochlear site of action. Hear. Res. 144:2000;196-204.
17. Currier M.F., McClimans C.D., Barna-Lloyd G. Hexachlorobenzene blood levels and the health status of men employed in the manufacture of chlorinated solvents. J. Toxicol. Environ. Health. 6:1980;367-377.
18. D'Andrea P., Veronesi V., Bicego M., Melchionda S., Zelante L., Di Iorio E., Bruzzone R., Gasparini P. Hearing loss: frequency and functional studies of the most common connexin26 alleles. Biochem. Biophys. Res. Commun. 296:2002;685-691.
19. De Matteis F., Gibbs A.H., Martin S.R., Milek R.L. Labelling in vivo and chirality of griseofulvin-derived. N -alkylated protoporphyrins Biochem. J. 280(Pt 3):1991;813-816.
20. Engstrom B. Fusion of stereocilia on inner hair cells in man and in the rabbit, rat and guinea pig. Scand. Audiol. 13:1984;87-92.
21. Erturk E., Lambrecht R.W., Peters H.A., Cripps D.J., Gocmen A., Morris C.R., Bryan G.T. Oncogenicity of hexachlorobenzene. IARC Sci. Publ. 77:1986;417-423.
22. Fechter L.D., Liu Y., Herr D.W., Crofton K.M. Trichloroethylene ototoxicity: evidence for a cochlear origin. Toxicol. Sci. 42:1998;28-35.
23. Foster W.G., Pentick J.A., McMahon A., Lecavalier P.R. Body distribution and endocrine toxicity of hexachlorobenzene (HCB) in the female rat. J. Appl. Toxicol. 13:1993;79-83.
24. Goldey E.S., Crofton K.M. Thyroxine replacement attenuates hypothyroxinemia, hearing loss, and motor deficits following developmental exposure to Aroclor 1254 in rats. Toxicol. Sci. 45:1998;94-105.
25. Goldey E.S., Taylor D.H. Developmental neurotoxicity following premating maternal exposure to hexachlorobenzene in rats. Neurotoxicol. Teratol. 14:1992;15-21.
26. Grant D.L., Phillips W.E., Hatina G.V. Effect of hexachlorobenzene on reproduction in the rat. Arch. Environ. Contam. Toxicol. 5:1977;207-216.
27. Hahn M.E., Goldstein J.A., Linko P., Gasiewicz T.A. Interaction of hexachlorobenzene with the receptor for 2,3,7,8-tetrachlorodibenzo-. p -dioxin in vitro and in vivo. Evidence that hexachlorobenzene is a weak Ah receptor agonist Arch. Biochem. Biophys. 270:1989;344-355.
28. Hallgren S., Darnerud P.O. Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats-testing interactions and mechanisms for thyroid hormone effects. Toxicology. 177:2002;227-243.
29. Jaspers R.M., Muijser H., Lammers J.H., Kulig B.M. Mid-frequency hearing loss and reduction of acoustic startle responding in rats following trichloroethylene exposure. Neurotoxicol. Teratol. 15:1993;407-412.
30. Johnson A.C., Canlon B. Toluene exposure affects the functional activity of the outer hair cells. Hear. Res. 72:1994;189-196.
31. Kleiman de Pisarev D.L., Sancovich H.A., Ferramola de Sancovich A.M. Enhanced thyroxine metabolism in hexachlorobenzene-intoxicated rats. J. Endocrinol. Invest. 12:1989;767-772.
32. Kuczynska-Sekieta K., Rudnicka J. [Thyroid insufficiency in the course of chronic benzene poisoning]. Wiad Lek. 19:1966;1275-1276.
33. Langer P., Kocan A., Tajtakova M., Petrik J., Chovancova J., Drobna B., Jursa S., Pavuk M., Koska J., Trnovec T., Sebokova E., Klimes I. Possible effects of polychlorinated biphenyls and organochlorinated pesticides on the thyroid after long-term exposure to heavy environmental pollution. J. Occup. Environ. Med. 45:2003;526-532.
34. Loaiza-Perez A.I., Seisdedos M.T., Kleiman de Pisarev D.L., Sancovich H.A., Randi A.S., Ferramola de Sancovich A.M., Santisteban P. Hexachlorobenzene, a dioxin-type compound, increases malic enzyme gene transcription through a mechanism involving the thyroid hormone response element. Endocrinology. 140:1999;4142-4151.
35. Makitie A.A., Pirvola U., Pyykko I., Sakakibara H., Riihimaki V., Ylikoski J. The ototoxic interaction of styrene and noise. Hear. Res. 179:2003;9-20.
36. Mansour M., Scheunert I., Viswanathan R., Korte F. Assessment of the persistence of hexachlorobenzene in the ecosphere. IARC Sci. Publ. 77:1986;53-59.
37. Mra Z., Wax M.K. Effects of acute thyroxin depletion on hearing in humans. Laryngoscope. 109:1999;343-350.
38. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1982;Academic Press, Sydney, Australia.
39. Peters H.A., Cripps D.J., Gocmen A., Erturk E., Bryan G.T., Morris C.R. Neurotoxicity of hexachlorobenzene-induced porphyria turcica. IARC Sci. Publ. 77:1986;575-579.
40. Plante I., Charbonneau M., Cyr D.G. Decreased gap junctional intercellular communication in hexachlorobenzene-induced gender-specific hepatic tumor formation in the rat. Carcinogenesis. 23:2002;1243-1249.
41. Poon R., Chu I., Bjarnason S., Potvin M., Vincent R., Miller R.B., Valli V.E. Inhalation toxicity study of methanol, toluene, and methanol/toluene mixtures in rats: effects of 28 days exposure. Toxicol. Ind. Health. 10:1994;231-245.
42. Pryor G.T., Rebert C.S., Howd R.A. Hearing loss in rats caused by inhalation of mixed xylenes and styrene. J. Appl. Toxicol. 7:1987;55-61.
43. Rabionet R., Lopez-Bigas N., Arbones M.L., Estivill X. Connexin mutations in hearing loss, dermatological and neurological disorders. Trends Mol. Med. 8:2002;205-212.
44. Rebert C.S., Hall T.A. The neuroepidemiology of styrene: a critical review of representative literature. Crit. Rev. Toxicol. 24(Suppl):1994;S57- S106.
45. Rebert C.S., Schwartz R.W., Svendsgaard D.J., Pryor G.T., Boyes W.K. Combined effects of paired solvents on the rat's auditory system. Toxicology. 105:1995;345-354.
46. Rozman K., Gorski J.R., Rozman P., Parkinson A. Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. Toxicol. Lett. 30:1986;71-78.
47. Schielen P., Den Besten C., Vos J.G., Van Bladeren P.J., Seinen W., Bloksma N. Immune effects of hexachlorobenzene in the rat: role of metabolism in a 13-week feeding study. Toxicol. Appl. Pharmacol. 131:1995;37-43.
48. Shiraishi F., Okumura T., Nomachi M., Serizawa S., Nishikawa J., Edmonds J.S., Shiraishi H., Morita M. Estrogenic and thyroid hormone activity of a series of hydroxy-polychlorinated biphenyls. Chemosphere. 52:2003;33-42.
49. Sullivan M.J., Rarey K.E., Conolly R.B. Ototoxicity of toluene in rats. Neurotoxicol. Teratol. 10:1988;525-530.
50. Tobin P. Known and potential sources of hexachlorobenzene. IARC Sci. Publ. 77:1986;3-11.
51. Tuttle, J.R., 1979. A survey of the sources, uses and environmental distribution of hexachlorobenzene in Alberta, Saskatchewan, Manitoba and the Northwest territories. Service de la protection de l'environnement, Environnement Canada, Edmonton (Alberta)
52. Uhnak J., Veningerova M., Madaric A., Szokolay A. Dynamics of hexachlorobenzene residues in the food chain. IARC Sci. Publ. 77:1986;109-113.
53. van Birgelen A.P. Hexachlorobenzene as a possible major contributor to the dioxin activity of human milk. Environ. Health Perspect. 106:1998;683-688.
54. van Raaij J.A., van den Berg K.J., Notten W.R. Hexachlorobenzene and its metabolites pentachlorophenol and tetrachlorohydroquinone: interaction with thyroxine binding sites of rat thyroid hormone carriers ex vivo and in vitro. Toxicol. Lett. 59:1991;101-107.
55. van Raaij J.A., Frijters C.M., van den Berg K.J. Hexachlorobenzene- induced hypothyroidism. Involvement of different mechanisms by parent compound and metabolite. Biochem. Pharmacol. 46:1993;1385-1391.
56. van Raaij J.A., Kaptein E., Visser T.J., van den Berg K.J. Increased glucuronidation of thyroid hormone in hexachlorobenzene-treated rats. Biochem. Pharmacol. 45:1993;627-631.
57. Visser T.J., Kaptein E., van Toor H., van Raaij J.A., van den Berg K.J., Joe C.T., van Engelen J.G., Brouwer A. Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions. Endocrinology. 133:1993;2177-2186.
58. Wingren G.B., Axelson O. Occupational and environmental determinants for benign thyroid disease and follicular thyroid cancer. Int. J. Occup. Environ. Health. 3:1997;89-94.
59. Yano B.L., Dittenber D.A., Albee R.R., Mattsson J.L. Abnormal auditory brainstem responses and cochlear pathology in rats induced by an exaggerated styrene exposure regimen. Toxicol. Pathol. 20:1992;1-6.