Carboxymethylcellulose-stabilized collagenous rhOP-1 device - A novel carrier biomaterial for the repair of mandibular continuity defects

Journal of Biomedical Materials Research - Part A

Volumn 68, Issue 2, 2004, Pages 219-226

  Wang, Huiming ^a   Springer, Ingo N G ^a   Schildberg, Hendrik ^a   Acil, Yahya ^a   Ludwig, Klaus ^a   Rueger, David R ^b   Terheyden, Hendrik ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b Stryker Orthopaedics   (United States)

Author keywords

Biomechanical testing; Carboxymethylcellulose; Carrier biomaterials; Collagenous matrix; Osteogenic protein

Indexed keywords

LIQUIDS; PROTEINS; TENSILE PROPERTIES; TITANIUM PLATING;

HEMIMANDIBLES; MANDIBULAR CONTINUITY DEFECTS; SPACE-KEEPING PROPERTIES;

BIOMATERIALS;

BIOMATERIAL; CARBOXYMETHYLCELLULOSE; RECOMBINANT OSTEOGENIC PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BONE DEVELOPMENT; BONE PLATE; BONE PROSTHESIS; BONE REGENERATION; BONE REMODELING; COMPARATIVE STUDY; CONTROLLED STUDY; DEVICE; FEMALE; JAW MALFORMATION; JOINT STABILITY; MANDIBLE RECONSTRUCTION; NONHUMAN; PLASTICITY;

EID: 1942421596     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.a.10129     Document Type: Article

References (27)

1. Springer ING, Suhr M, Fleiner B. Adaptive adjustment of the adolescent porcine mandibular condyle. Bone 2002;31:1190-1195.
2. Young MP, Worthington HV, Lloyd RE, Drucker DB, Sloan P, Carter DH. Bone collected during dental implant surgery: a clinical and histological study. Clin Oral Implants Res 2002;13:298-303.
3. Axhausen G. Die histologischen und klinischenGesetze der freien Osteoblastik aufgrund von Tierversuchen. Langenbecks Arch Klin Chir 1908;88:23-145.
4. Ullmark G. Bigger size and defatting of bone chips will increase cup stability. Arch Orthop Trauma Surg 2000;120:445-447.
5. Ozkaynak E, Rueger DC, Drier EA, Corbett C, Ridge RJ, Sampath TK, Oppermann H. OP-1 cDNA encodes an osteogenic protein in the TGF-beta family. Embo J 1990;9:2085-2093.
6. Wang EA, Rosen V, D'Alessandro JS, Bauduy M, Cordes P, Harada T, Israel DI, Hewick RM, Kerns KM, LaPan P, et al. Recombinant human bone morphogenetic protein induces bone formation. Proc Natl Acad Sci USA 1990;87:2220-2224.
7. Sampath TK, Maliakal JC, Hauschka PV, Jones WK, Sasak H, Tucker RF, White KH, Coughlin JE, Tucker MM, Pang RH, et al. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J Biol Chem 1992;267:20352-20362.
8. Terheyden H, Jepsen S, Rueger DR. Mandibular reconstruction in miniature pigs with prefabricated vascularized bone grafts using recombinant human osteogenic protein-1: a preliminary study. Int J Oral Maxillofac Surg 1999;28:461-463.
9. Ripamonti U, Van Den Heever B, Sampath TK, Tucker MM, Rueger DC, Reddi AH. Complete regeneration of bone in the baboon by recombinant human osteogenic protein-1 (hOP-1, bone morphogenetic protein-7). Growth Factors 1996;13:273-289.
10. Ripamonti U, Duneas N. Tissue morphogenesis and regeneration by bone morphogenetic proteins. Plast Reconstr Surg 1998;101:227-239.
11. Toriumi DM, Kotler HS, Luxenberg DP, Holtrop ME, Wang EA. Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation. Arch Otolaryngol Head Neck Surg 1991;117:1101-1112.
12. Toriumi DM, O'Grady K, Horlbeck DM, Desai D, Turek TJ, Wozney J. Mandibular reconstruction using bone morphogenetic protein 2: long-term follow-up in a canine model. Laryngoscope 1999;109:1481-1489.
13. Terheyden H, Jepsen S, Vogeler S, Tucker M, Rueger DC. Recombinant human osteogenic protein 1 in the rat mandibular augmentation model: differences in morphology of the newly formed bone are dependent on the type of carrier. Mund Kiefer Gesichtschir 1997;1:272-275.
14. Acil Y, Springer ING, Broek V, Terheyden H, Jepsen S. Effects of bone morphogenetic protein-7 stimulation on osteoblasts cultured on different biomaterials. J Cell Biochem 2002;86:90-98.
15. Boyne PJ, Nakamura A, Shabahang S. Evaluation of the long-term effect of function on rhBMP-2 regenerated hemimandibulectomy defects. Br J Oral Maxillofac Surg 1999;37:344-352.
16. Santa-Comba A, Pereira A, Lemos R, Santos D, Amarante J, Pinto M, Tavares P, Bahia F. Evaluation of carboxymethylcellulose, hydroxypropylmethylcellulose, and aluminum hydroxide as potential carriers for rhBMP-2. J Biomed Mater Res 2001;55:396-400.
17. Rodgers JB, Vasconez HC, Wells MD, DeLuca PP, Faugere MC, Fink BF, Hamilton D. Two lyophilized polymer matrix recombinant human bone morphogenetic protein-2 carriers in rabbit calvarial defects. J Craniofac Surg 1998;9:147-153.
18. Terato K, DeArmey DA, Ye XJ, Griffiths MM, Cremer MA. The mechanism of autoantibody formation to cartilage in rheumatoid arthritis: possible cross-reaction of antibodies to dietary collagens with autologous type II collagen. Clin Immunol Immunopathol 1996;79:142-154.
19. Trautinger F, Kokoschka EM, Menzel EJ. Antibody formation against human collagen and C1q in response to a bovine collagen implant. Arch Dermatol Res 1991;283:395-399.
20. Terheyden H, Jepsen S, Moller B, Tucker MM, Rueger DC. Sinus floor augmentation with simultaneous placement of dental implants using a combination of deproteinized bone xenografts and recombinant human osteogenic protein-1. A histometric study in miniature pigs. Clin Oral Implants Res 1999;10:510-521.
21. Friedlaender GE. OP-1 clinical studies. J Bone Joint Surg Am 2001;83-A:S160-161.
22. Boyne PJ, Marx RE, Nevins M, Triplett G, Lazaro E, Lilly LC, Alder M, Nummikoski P. A feasibility study evaluating rhBMP-2/absorbable collagen sponge for maxillary sinus floor augmentation. Int J Periodontics Restorative Dent 1997;17:11-25.
23. Geesink RG, Hoefnagels NH, Bulstra SK. Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect. J Bone Joint Surg Br 1999;81:710-718.
24. Yasko AW, Lane JM, Fellinger EJ, Rosen V, Wozney JM, Wang EA. The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. J Bone Joint Surg Am 1992;74:659-670.
25. Terheyden H, Jepsen S, Moller B, Rueger D. Sinus floor augmentation with simultaneous implant insertion using recombinant human osteogenic protein-1. Laryngorhinootologie 2001;80:47-51.
26. Aaboe M, Pinholt EM, Hjorting-Hansen E. Healing of experimentally created defects: a review. Br J Oral Maxillofac Surg 1995;33:312-318.
27. Cook SD, Baffes GC, Wolfe MW, Sampath TK, Rueger DC. Recombinant human bone morphogenetic protein-7 induces healing in a canine long-bone segmental defect model. Clin Orthop 1994;301:302-312.