Burkholderia cepacia Infections Associated with Intrinsically Contaminated Ultrasound Gel: The Role of Microbial Degradation of Parabens

Infection Control and Hospital Epidemiology

Volumn 25, Issue 4, 2004, Pages 291-296

  Hutchinson, Jim ^a,b,f   Runge, Wendy ^c   Mulvey, Mike ^d   Norris, Gail ^a   Yetman, Marion ^a   Valkova, Nelly ^e   Villemur, Richard ^e   Lepine, Francois ^e  

^a Health Care Corporation of St John's   (Canada)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^c CALGARY HEALTH REGION   (Canada)

^d PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^e INRS INSTITUT ARMAND FRAPPIER   (Canada)

^f Health Sciences Centre St John's   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER;

ADULT; AGED; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIUM CONTAMINATION; BACTERIUM ISOLATE; BLOOD SAMPLING; CANADA; CLINICAL ARTICLE; ENTEROBACTER CLOACAE; FEMALE; GEL; HUMAN; MALE; MEDICAL RECORD; MICROBIAL DEGRADATION; PULSED FIELD GEL ELECTROPHORESIS; REVIEW; ULTRASOUND;

AGED; ALBERTA; BURKHOLDERIA CEPACIA; BURKHOLDERIA INFECTIONS; CROSS INFECTION; DISEASE OUTBREAKS; ELECTROPHORESIS, GEL, PULSED-FIELD; EQUIPMENT CONTAMINATION; GELS; HUMANS; INFECTION CONTROL; MALE; MIDDLE AGED; NEWFOUNDLAND; PARABENS; RETROSPECTIVE STUDIES;

EID: 1942420336     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/502394     Document Type: Review

References (32)

1. Burkholder W. Sour skin, a bacterial rot of onion bulbs. Phytopathology 1950;40:115-118.
2. Govan JR, Hughes JE, Vandamme P. Burkholderia cepacia: medical, taxonomic and ecological issues. J Med Microbiol 1996;45:395-407.
3. Glass S, Govan JR. Pseudomonas cepacia: fatal pulmonary infection in a patient with cystic fibrosis. J Infect 1986;13:157-158.
4. Govan JR, Brown PH, Maddison J, et al. Evidence for transmission of Pseudomonas cepacia by social contact in cystic fibrosis. Lancet 1993;342:15-19.
5. Poe RH, Marcus HR, Emerson GL. Lung abscess due to Pseudomonas cepacia. Am Rev Respir Dis 1977;115:861-865.
6. Hamill RJ, Houston ED, Georghiou PR, et al. An outbreak of Burkholderia (formerly Pseudomonas) cepacia respiratory tract colonization and infection associated with nebulized albuterol therapy. Ann Intern Med 1995;122:762-766.
7. Sobel JD, Hashman N, Reinherz G, Merzbach D. Nosocomial Pseudomonas cepacia infection associated with chlorhexidine contamination. Am J Med 1982;73:183-186.
8. Henderson DK, Baptiste R, Parrillo J, Gill VJ. Indolent epidemic of Pseudomonas cepacia bacteremia and pseudobacteremia in an intensive care unit traced to a contaminated blood gas analyzer. Am J Med 1988;84:75-81.
9. Conly JM, Klass L, Larson L, Kennedy J, Low DE, Harding GK. Pseudomonas cepacia colonization and infection in intensive care units. CMAJ 1986;134:363-366.
10. Borghans JG, Hosli MT, Olsen H, Ravn EM, Siboni K, Sogaard P. Pseudomonas cepacia bacteraemia due to intrinsic contamination of an anaesthetic: bacteriological and serological observations. Acta Pathologica Microbiologica Scandinavica 1979;87:15-20.
11. Matrician L, Ange G, Burns S, et al. Outbreak of nosocomial Burkholderia cepacia infection and colonization associated with intrinsically contaminated mouthwash. Infect Control Hosp Epidemiol 2000;21:739-741.
12. Muradali D, Gold WL, Phillips A, Wilson S. Can ultrasound probes and coupling gel be a source of nosocomial infection in patients undergoing sonography? An in vivo and in vitro study. AJR Am J Roentgenol 1995;164:1521-1524.
13. Ohara T, Itoh Y, Itoh K. Utrasound instruments as possible vectors of staphylococcal infection. J Hosp Infect 1998;40:73-77.
14. Spencer P, Spencer RC. Ultrasound scanning of post-operative wounds: the risks of cross-infection. Clin Radiol 1988;39:245-246.
15. Abdullah BJ, Mohd Yusof MY, Khoo BH. Physical methods of reducing the transmission of nosocomial infections via ultrasound and probe. Clin Radiol 1998;53:212-214.
16. O'Doherty AJ, Murphy PG, Curran RA. Risk of Staphylococcus aureus transmission during ultrasound investigation. J Ultrasound Med 1989;8:619-620.
17. Keizur JJ, Lavin B, Leidich RB. Iatrogenic urinary tract infection with Pseudomonas cepacia after transrectal ultrasound guided needle biopsy of the prostate. J Urol 1993;149:523-526.
18. Zani F, Minutello A, Maggi L, Santi P, Mazza P. Evaluation of preservative effectiveness in pharmaceutical products: the use of a wild strain of Pseudomonas cepacia. J Appl Microbiol 1997;83:322-326.
19. Warth AD. Relationships between the resistance of yeasts to acetic, propanoic and benzoic acids and to methyl paraben and pH. Int J Food Microbiol 1989;8:343-349.
20. Close JA, Neilsen PA. Resistance of a strain of Pseudomonas cepacia to esters of p-hydroxybenzoic acid. Appl Environ Microbiol 1976;31:718-722.
21. Valkova N, Lepine F, Valeanu L, et al. Hydrolysis of 4-hydroxybenzoic acid esters (parabens) and their aerobic transformation into phenol by the resistant Enterobacter cloacae strain EM. Appl Environ Microbiol 2001;67:2404-2409.
22. Hosokawa K, Park NH, Inaoka T, Itoh Y, Ochi K. Streptomycin-resistant (rpsL) or rifampicin-resistant (rpoB) mutation in Pseudomonas putida KH146-2 confers enhanced tolerance to organic chemicals. Environ Microbiol 2002;4:703-712.
23. Suemitsu R, Horiuchi K, Yanagawase S, Okamatsu T. Biotransformation activity of Pseudomonas cepacia on p-hydroxybenzoates and benzalkonium chloride. Journal of Antibacterial and Antifungal Agents 1990;18:579-582.
24. Swaminathan B, Barrett TJ, Hunter SB, Tauxe RV. PulseNet: the molecular subtyping network for foodborne bacterial disease surveillance, United States. Emerg Infect Dis 2001;7:382-389.
25. Goldstein R, Sun L, Jiang RZ, Sajjan U, Forstner JF, Campanelli C. Structurally variant classes of pilus appendage fibers coexpressed from Burkholderia (Pseudomonas) cepacia. J Bacteriol 1995;177:1039-1052.
26. Tenover FC, Arbeit RD, Goering RV. How to select and interpret molecular strain typing methods for epidemiological studies of bacterial infections: a review for healthcare epidemiologists. Infect Control Hosp Epidemiol 1997;18:426-439.
27. Valkova N, Lepine F, Bollet C, Dupont M, Villemur R. PrbA, a gene coding for an esterase hydrolyzing parabens in Enterobacter cloacae and Enterobacter gergoviae strains. J Bacteriol 2002;184:5011-5017.
28. Pyke M, Hirji Z, Havill D, et al. Ultrasound (U/S) Gel: A Potential Source of Microbiologic Contamination. Victoria, British Columbia, Canada: Canadian Association for Clinical Microbiology and Infectious Diseases; 2001.
29. Valkova N, Lepine F, Labrie L, Dupont M, Beaudet R. Purification and characterization of PrbA, a new esterase from Exterobacter cloacae hydrolyzing the esters of 4-hydroxybenzoic acid (parabens). J Biol Chem 2003; 278:12779-12785.
30. Weist K, Wendt C, Petersen LR, Versmold H, Ruden H. An outbreak of pyodermas among neonates caused by ultrasound gel contaminated with methicillin-susceptible Staphylococcus aureus. Infect Control Hosp Epidemiol 2000;21:761-764.
31. Gaillot O, Maruejouls C, Abachin E, et al. Nosocomial outbreak of Klebsiella pneumoniae producing SHV-5 extended-spectrum beta-lactamase, originating from a contaminated ultrasonography coupling gel. J Clin Microbiol 1998;36:1357-1360.
32. Howe RS, Wheeler C, Mastroianni L Jr, Blasco L, Tureck R. Pelvic infection after transvaginal ultrasound-guided ovum retrieval. Fertil Steril 1988;49:726-728.