The mysteries of a platelet adhesion receptor

Blood

Volumn 105, Issue 11, 2005, Pages 4154-4155

  Chen, Junmei ^a   López, José A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPEPTIDE; GLYCOPROTEIN IB; LEUCINE; THROMBOCYTE RECEPTOR; VON WILLEBRAND FACTOR;

AUTOSOMAL DOMINANT INHERITANCE; BETA SHEET; BLEEDING; CELL MEMBRANE; GENE CONTROL; GENE DELETION; GENE MUTATION; GENE SEQUENCE; LIPID RAFT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; REVIEW; THROMBOCYTE ADHESION; VON WILLEBRAND DISEASE;

EID: 19344367862     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2005-03-1141     Document Type: Review

References (5)

1. Huizinga EG, Tsuji S, Romijn RA, et al. Structures of glycoprotein Ibα and its complex with von Willebrand factor A1 domain. Science. 2002;297:1176-1179.
2. Dong J, Schade AJ, Romo GM, et al. Novel gain-of-function mutations of platelet glycoprotein Ibα by valine mutagenesis in the Cys-Cys248 disulfide loop: functional analysis under static and dynamic conditions. J Biol Chem. 2000;275:27663-27670.
3. López JA, Ludwig EH, McCarthy BJ. Polymorphism of human glycoprotein Ibα results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region: structure/function implications. J Biol Chem. 1992;267:10055-10061.
4. Shrimpton CN, Borthakur G, Larrucea S, et al. Localization of the adhesion receptor glycoprotein Ib-IX-V complex to lipid rafts is required for platelet adhesion and activation. J Exp Med. 2002;196:1057-1066.
5. 2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complex. J Biol Chem. 1994;269:18287-18290.