Properties of anti-gp41 core structure antibodies, which compete with sera of HIV-1-infected patients

Microbes and Infection

Volumn 7, Issue 4, 2005, Pages 650-657

  Usami, Osamu ^a   Xiao, Peng ^a   Ling, Hong ^b   Liu, Yi ^c   Nakasone, Tadashi ^d   Hattori, Toshio ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c AIR FORCE GENERAL HOSPITAL   (China)

^d NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Core structure; gp41; HIV 1; LTS; PCP; Sera

Indexed keywords

GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 50.69; MONOCLONAL ANTIBODY 98.6; MONOCLONAL ANTIBODY T26; MONOMER; OLIGOMER; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANTIGEN BINDING; ANTIGENICITY; ARTICLE; BINDING COMPETITION; BINDING SITE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; IMMUNE RESPONSE; MALE; NUCLEOTIDE SEQUENCE; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; PROTEIN STRUCTURE; SERUM;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CELL LINE; FLOW CYTOMETRY; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP41; HIV INFECTIONS; HIV LONG-TERM SURVIVORS; HIV-1; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PNEUMONIA, PNEUMOCYSTIS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; PNEUMOCYSTIS;

EID: 19344367504     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micinf.2005.01.007     Document Type: Article

References (33)

1. M. Lu, S.C. Blacklow, and P.S. Kim A trimeric structural domain of the HIV-1 transmembrane glycoprotein Nat. Struct. Biol. 2 1995 1075 1082
2. D.C. Chan, D. Fass, J.M. Berger, and P.S. Kim Core structure of gp41 from the HIV envelope glycoprotein Cell 89 1997 263 273
3. W. Weissenhorn, A. Dessen, S.C. Harrison, J.J. Skehel, and D.C. Wiley Atomic structure of the ectodomain from HIV-1 gp41 Nature 387 1997 426 430
4. J.Y. Xu, M.K. Gorny, T. Palker, S. Karwowska, and S. Zolla-Pazner Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using 10 human monoclonal antibodies J. Virol. 65 1991 4832 4838
5. T. Hattori, H. Komoda, S. Pahwa, M. Tateyama, X. Zhang, and Y. Xu Decline of anti-DP107 antibody associated with clinical progression AIDS 12 1998 1557 1559
6. R.A. Furuta, C.T. Wild, Y. Weng, and C.D. Weiss Capture of an early fusion-active conformation of HIV-1 gp41 Nat. Struct. Biol. 5 1998 276 279
7. Y. Taniguchi, S. Zolla-Pazner, Y. Xu, X. Zhang, S. Takeda, and T. Hattori Human monoclonal antibody 98-6 reacts with the fusogenic form of gp41 Virology 273 2000 333 340
8. M.K. Gorny, T.C. VanCott, C. Williams, K. Revesz, and S. Zolla-Pazner Effects of oligomerization on the epitopes of the human immunodeficiency virus type 1 envelope glycoproteins Virology 267 2000 220 228
9. P.L. Earl, C.C. Broder, R.W. Doms, and B. Moss Epitope map of human immunodeficiency virus type 1 gp41 derived from 47 monoclonal antibodies produced by immunization with oligomeric envelope protein J. Virol. 71 1997 2674 2684
10. P.L. Earl, C.C. Broder, D. Long, S.A. Lee, J. Peterson, and S. Chakrabarti Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities J. Virol. 68 1994 3015 3026
11. N.R. Kilgore, K. Salzwedel, M. Reddick, G.P. Allaway, and C.T. Wild Direct evidence that C-peptide inhibitors of human immunodeficiency virus type 1 entry bind to the gp41 N-helical domain in receptor-activated viral envelope J. Virol. 77 2003 7669 7672
12. E. de Rosny, R. Vassell, P.T. Wingfield, C.T. Wild, and C.D. Weiss Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein J. Virol. 75 2001 8859 8863
13. Q.J. Sattentau, and J.P. Moore Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding J. Exp. Med. 174 1991 407 415
14. Q.J. Sattentau, S. Zolla-Pazner, and P. Poignard Epitope exposure on functional, oligomeric HIV-1 gp41 molecules Virology 206 1995 713 717
15. S. Laal, S. Burda, M.K. Gorny, S. Karwowska, A. Buchbinder, and S. Zolla-Pazner Synergistic neutralization of human immunodeficiency virus type 1 by combinations of human monoclonal antibodies J. Virol. 68 1994 4001 4008
16. J.S. McDougal, M.S. Kennedy, S.L. Orloff, J.K. Nicholson, and T.J. Spira Mechanisms of human immunodeficiency virus type 1 (HIV-1) neutralization: irreversible inactivation of infectivity by anti-HIV-1 antibody J. Virol. 70 1996 5236 5245
17. C.M. Finnegan, W. Berg, G.K. Lewis, and A.L. DeVico Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion J. Virol. 76 2002 12123 12134
18. L.D. Loomis-Price, J.H. Cox, J.R. Mascola, T.C. VanCott, N.L. Michael, and T.R. Fouts Correlation between humoral responses to human immunodeficiency virus type 1 envelope and disease progression in early-stage infection J. Infect. Dis. 178 1998 1306 1316
19. M. Muhlbacher, M. Spruth, F. Siegel, R. Zangerle, and M.P. Dierich Longitudinal study of antibody reactivity against HIV-1 envelope and a peptide representing a conserved site on Gp41 in HIV-1-infected patients Immunobiology 200 1999 295 305
20. T. Yamada, and A. Iwamoto Expression of a novel Nef epitope on the surface of HIV type 1-infected cells AIDS Res. Hum. Retroviruses 15 1999 1001 1009
21. A. Propato, E. Schiaffella, E. Vicenzi, V. Francavilla, L. Baloni, and M. Paroli Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity Hum. Immunol. 62 2001 561 576
22. E. Keoshkerian, L.J. Ashton, D.G. Smith, J.B. Ziegler, J.M. Kaldor, and D.A. Cooper Effector HIV-specific cytotoxic T-lymphocyte activity in long-term nonprogressors: associations with viral replication and progression J. Med. Virol. 71 2003 483 491
23. M.M. Kitahata, T.D. Koepsell, R.A. Deyo, C.L. Maxwell, W.T. Dodge, and E.H. Wagner Physicians' experience with the acquired immunodeficiency syndrome as a factor in patients' survival New Engl. J. Med. 334 1996 701 706
24. M.K. Gorny, and S. Zolla-Pazner Recognition by human monoclonal antibodies of free and complexed peptides representing the prefusogenic and fusogenic forms of human immunodeficiency virus type 1 gp41 J. Virol. 74 2000 6186 6192
25. A. Pinter, W.J. Honnen, S.A. Tilley, C. Bona, H. Zaghouani, and M.K. Gorny Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1 J. Virol. 63 1989 2674 2679
26. B. Chesebro, and K. Wehrly Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivity J. Virol. 62 1988 3779 3788
27. Y. Maeda, S. Matsushita, T. Hattori, T. Murakami, and K. Takatsuki Changes in the reactivity and neutralizing activity of a type-specific neutralizing monoclonal antibody induced by interaction of soluble CD4 with gp120 AIDS Res. Hum. Retroviruses 8 1992 2049 2054
28. S. Zolla-Pazner, M.K. Gorny, W.J. Honnen, and A. Pinter Reinterpretation of human immunodeficiency virus western blot patterns New Engl. J. Med. 320 1989 1280 1281
29. Y.H. Abacioglu, T.R. Fouts, J.D. Laman, E. Claassen, S.H. Pincus, and J.P. Moore Epitope mapping and topology of baculovirus-expressed HIV-1 gp160 determined with a panel of murine monoclonal antibodies AIDS Res. Hum. Retroviruses 10 1994 371 381
30. Y.G. Kuznetsov, J.G. Victoria, W.E. Robinson Jr., and A. McPherson Atomic force microscopy investigation of human immunodeficiency virus (HIV) and HIV-infected lymphocytes J. Virol. 77 2003 11896 11909
31. T.L. Benfield Clinical and experimental studies on inflammatory mediators during AIDS-associated Pneumocystis carinii pneumonia Dan. Med. Bull. 50 2003 161 176
32. A.L. Laursen, B.N. Jensen, and P.L. Andersen Local antibodies against Pneumocystis carinii in bronchoalveolar lavage fluid Eur. Respir. J. 7 1994 679 685
33. D. Israel-Biet, J. Cadranel, and P. Even Human immunodeficiency virus production by alveolar lymphocytes is increased during Pneumocystis carinii pneumonia Am. Rev. Respir. Dis. 148 1993 1308 1312