Droplet mass transfer, intradroplet nucleation and submicron particle production in two-phase flow of solvent-supercritical antisolvent emulsion

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volumn 261, Issue 1-3, 2005, Pages 163-176

  Dukhin, S S ^a,b   Shen, Y ^a   Dave, R ^a   Pfeffer, R ^a  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^b NONE   (United States)

Author keywords

Hydrodynamic relaxation time; Intradroplet nucleation; Long nucleation time; Nanoparticle formation; Solvent supercritical antisolvent emulsion; Supercritical two phase flow

Indexed keywords

COAGULATION; EMULSIONS; MASS TRANSFER; NUCLEATION; ORGANIC SOLVENTS; PARTICLE SIZE ANALYSIS; PHASE EQUILIBRIA; SUPERSATURATION; TWO PHASE FLOW;

DROPLET MASS TRANSFER; INTRADROPLET NUCLEATION; SOLVENT JET DISPERGATION; SUBMICRON PARTICLE PRODUCTION;

DROP FORMATION;

ALCOHOL; NANOPARTICLE; SOLVENT;

CHEMICAL PROCEDURES; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; DIFFUSION; EMULSION; HYDRODYNAMICS; PARTICLE SIZE; PRECIPITATION; PRIORITY JOURNAL; SUPERCRITICAL FLUID;

EID: 19344363257     PISSN: 09277757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfa.2004.11.038     Document Type: Conference Paper

References (48)

1. S.-D. Yeo, G.-B. Lim, P.G. Debenedetti, and H. Bernstein Biotechnol. Bioeng. 41 1993 341
2. S.-D. Yeo, P.G. Debenedetti, S.Y. Patro, and T.M. Przybycien Pharm. Sci. 83 1994 1651
3. M.A. Winters, B.L. Knutson, P.G. Debenedetti, H.G. Sparks, T.U. Przybycien, C.L. Stevenson, and S.J. Prestrelski Pharm. Sci. 85 1996 586
4. J. Jung, and M. Perrut J. Supercrit. Fluids 20 2001 179
5. A. Shariati, and C.J. Peters Curr. Opin. Solid State Mater. Sci. 7 2003 371
6. J. Texter Disper. Sci. Technol. 22 2001 49
7. D.J. Dixon, K.P. Johnston, and R.A. Bodmeier AIChE J. 39 1 1993 127
8. S.S. Dukhin, C. Zhu, R. Dave, R. Pfeffer, J.J. Luo, F. Chavez, and Y. Shen Colloids Surf. 229 2003 181
9. V. Krukonis Proceedings of the Annual AIChE Meeting San Francisco 1984
10. I. Kikic, A. Bertucco, and M. Lora E. Reverchon Proceedings of the Fourth Italian Conference on Supercritical Fluids and their Applications Capri, Italy, September 7-10 1997
11. J.O. Werling, and P.G. Debenedetti J. Supercrit. Fluids 16 1999 167
12. F. Chávez, P.G. Debenedetti, J.J. Luo, R.N. Dave, and R. Pfeffer Ind. Eng. Chem. Res. 42 2003 3156
13. B.G. Kyle Chemical and Process Thermodynamics 1984 Prentice-Hall New Jersey
14. T.L.T. Taylor, Supercritical Fluid Extraction, Wiley, New York, 1996.
15. H. Nishiumi, M. Fujita, and K. Agou Fluid Phase Equilib. 117 1996 356
16. T. Funazukuri, C.Y. Kong, and S. Kagei Ind. Eng. Chem. Res. 39 2000 835
17. C.J. Chang, C.-Y. Day, C.-M. Ko, and K.-L. Chiu Fluid Phase Equilib. 131 1997 243
18. G.S. Gurdial, S.J. Macnaughton, D.L. Tomasko, and N.R. Foster Ind. Eng. Chem. Res. 32 1993 1488
19. L.A. Galicia-Luna, A. Ortega-Rodriguez, and D. Richon J. Chem. Eng. Data 45 2000 1218
20. M.J.L. De la Cruz, and L.A. Galicia-Luna ELDATA: Int. Electron. J. Physico-Chem. Data 5 1999 157
21. M.R. Prausnitz, D.V. McAllister, S. Kaushik, P.N. Patel, J.L. Mayberry, and M.G. Allen Am. Soc. Mech. Eng. Bioeng. Division (Publication) BED 42 1999 89
22. J.P. Canselier, H. Delmas, and A.M. Wilheim J. Disper. Sci. Technol. 23 2002 333
23. P. Chattopadhyay, and R.B. Gupta Ind. Eng. Chem. Res. 40 2001 3530
24. P. Chattopadhyay, and R.B. Gupta Int. J. Pharm. 228 2001 19
25. V. Shroder, and H. Schubert Colloids Surf. 152 1999 103
26. G.T. Vladisavljevic, U. Lambrich, M. Nakajima, and H. Schubert Colloids Surf. 232 2004 199
27. J. Lyklema Fundamental of Interface and Colloid Science, vol. 1, Section 2.16 1993 Academic Press
28. L. Landau, and E. Lifshitz Mechanics of Continuous Media-Hydrodynamics 1958 Addison-Wesley Publishing Company Reading, MA
29. M. von Smoluchowski Z. Phys. Chem. 92 1917 129
30. T.G.M. Van de Ven, and S.G. Mason Colloid Polym. Sci. 25 1977 468
31. A.H. Levebre Atomization and Spray 1989 Taylor and Francis Hemisphere Publishing Co. New York
32. S.P. Lin, and R.D. Reitz Annu. Rev. Fluid Mech. 30 1998 85
33. C.C. Miese Ind. Eng. Chem. 47 1955 1690
34. M.G. McCarthy, and N.A. Malloy Chem. J. Eng. 7 1974 1
35. P.H. Schweitzer J. Appl. Phys. 8 1937 513
36. Y. Tanasawa, and S. Toyoda Trans. Jpn. Soc. Mech. 20 1954 300
37. N.N. Rulyov Colloids Surf. 152 1999 11
38. N.N. Rulyov, A. Maes, and V.J. Korolyov Colloids Surf. 175 2000 371
39. N.N. Rulyov Colloids Surf. 151 1999 283
40. N.N. Rulyov, and S.B. Karas Khimia i Teknol. Vody 12 1990 887
41. N.N. Rulyov, and B.P. Ryashchenko Khimiya i Teknol. Vody 11 1989 695
42. N.N. Rulyov Colloidn. Zh. 47 1985 721
43. N.N. Rulyov Colloids Surf. 192 2001 73
44. J. Laufer, US Nae. Advisory Comm Aeronautics Rep. 1954, N.
45. Sh. Lu, Y. Ding, and J. Guo Adv. Colloid Interf. Sci. 78 1998 197
46. S. Song, S. Lu, Y. Zhang, A. Lopez-Valdivieso, and T. Fort J. Disper. Sci. Technol. 25 2004 67
47. B.J. Meister, and G.F. Scheele AIChE J. 15 5 1969 689
48. H. Yu, and G.F. Scheele J. Multiphase Flow 2 1975 153