Treatment of chronic copper poisoning with oral application of ammonium molybdate and natrium sulphate in milk sheep;Behandlung einer chronischen kupfervergiftung mit oralem ammoniummolybdat und natriumsulfat bei milchschafen

Schweizer Archiv fur Tierheilkunde

Volumn 147, Issue 5, 2005, Pages 219-224

  Kupper, J ^a,d   Bidaut, A ^b   Waldvogel, A ^b   Emmenegger, B ^c   Naegeli, H ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c Tierarztpraxis am Rössliplatz AG

^d Institut fur Veterinarpharmakologie und toxikologie   (Switzerland)

Author keywords

Ammonium molybdate; Copper poisoning; Sheep; Sodium sulphate

Indexed keywords

AMMONIA; COPPER; MOLYBDIC ACID; PENICILLAMINE; SODIUM; SULFATE;

ANEMIA; ANIMAL MODEL; ANOREXIA; ARTICLE; BIOLOGICAL MONITORING; CLINICAL FEATURE; CONTROLLED STUDY; COPPER BLOOD LEVEL; CORRELATION ANALYSIS; DEPRESSION; FEEDING; FREQUENCY ANALYSIS; HEMOGLOBINURIA; HISTOPATHOLOGY; INTOXICATION; LIVER; MEDICAL ASSESSMENT; MILK PRODUCTION; NONHUMAN; SHEEP;

ADMINISTRATION, ORAL; ANIMALS; CATHARTICS; COPPER; FEMALE; MOLYBDENUM; POISONING; SHEEP; SHEEP DISEASES; SULFATES; TREATMENT OUTCOME;

OVIS; OVIS ARIES;

EID: 19344362972     PISSN: 00367281     EISSN: None     Source Type: Journal    
DOI: 10.1024/0036-7281.147.05.219     Document Type: Article

References (23)

1. Gooneratne S.R., Howell J.M., Gawthorne J.M.: Intravenous administration of thiomolybdate for the prevention and treatment of chronic copper poisoning in sheep. Brit. J. Nutrition 1981, 46: 457-467.
2. Gooneratne S.R., Chaplin R.K., Trent A.M., Christensen D.A.: Effect of tetrathiomolybdate administration on the excretion of copper, zinc, iron and molybdenum in sheep bile. Brit. Vet. J. 1989a, 145: 62-72.
3. Gooneratne S.R., Howell J.M., Gawthorne J.M., Kumaratilake J.S.: Subcellular distribution of copper in the kidneys of normal, copper-poisoned, and thiomolybdate-treated sheep. J. Inorg. Biochem. 1989b, 35: 23-36.
4. Haywood S., Dincer Z., Jasani B., Loughmn M.J.: Molybdenum-associated pituitary endocrinopathy in sheep treated with ammonium tetrathiomolybdate. J. Comp. Path. 2004, 103: 21-31.
5. Harker D.B.: The use of molybdenum for the prevention of nutritional copper poisoning in housed sheep. Vet. Rec. 1976, 99: 78-81.
6. Hidiroglou M., Heany D.P., Hartin K.E.: Copper poisoning in a flock of sheep. Copper excretion patterns after treatment with Molybdenum and Sulfur or Penicillamine. Can. Vet. J. 1984, 25: 377-382.
7. Humann-Ziehank E., Coenen M., Ganter M., Bickhardt K.: Long-term observation of subclinical chronic copper poisoning in two sheep breeds. J. Vet. Med. 2001, 48: 429-439.
8. Humphreys D.J.: Chronic copper poisoning. In: Veterinary Toxicology. Baillière Tindall, London, 1988, 38-39.
9. Ishmael J., Gopinath C., Howell J.M.: Experimental chronic copper toxicity in sheep; Biochemical and haematological studies during the development of lesions in the liver. Res. Vet. Sci. 1972, 13: 22-29.
10. Jeroch H., Drochner W., Simon O.: Ernährung landwirtschaftlicher Nutztiere. Verlag Ulmer Eugen, Stuttgart, 1999, 87.
11. Lorgue G., Lechenet J., Rivière A.: Précis de Toxicologie Clinique Vétérinaire. Edition du Pont Vétérinaire, Maisons-Alfort, 1987, 77.
12. Ogra Y., Ohmichi M., Suzuki K.T.: Mechanisms of selective copper removal by tetrathiomolybdate from methallothionein in LEC rats. Toxicology, 1996, 106: 75-83.
13. Ogra Y., Suzuki K.T.: Targeting of tetrathiomolybdate on the copper accumulating in the liver of LEC rats. Journal of Inorganic Biochemistry, 1998, 70: 49-55.
14. Pierson R.E., Aanes W.A.: Treatment of chronic copper poisoning in sheep. J. Am. Vet. Med. Assoc., 1958, 307-311.
15. Plumlee K.H.: Copper. In: Clinical Veterinary Toxicology. Mosby, St.Louis, 2003, 195-197.
16. Roder J.D.: Copper. In: Veterinary Toxicology, Butterworth-Hainemann, Woburn, 2001, 129-134.
17. Romeis B., Böck P., Denk H., Künzle H., Plenk jr. H., Rüschoff J., Sellner W.: Romeis Mikroskopische Technik. Hrsg. P. Böck, Urban und Schwarzenberg, München, 1989, 486.
18. Ross D.B.: The effect of oral ammonium molybdate and sodium sulphate given to lambs with high liver copper concentrations. Res. Vet. Sci. 1970, 11: 295-297.
19. Smith B.S.W., Field A.C., Suttle N.F.: Effect of intake of copper, molybdenum and sulphate on copper metabolism in the sheep. J Comp. Path. 1968, 78: 449-461.
20. Sugawam N., Li D., Sugawam C.: Removal of copper from the the liver of Long-Evans Cinnamon (LEC) rats by tetrathiomolybdate (TTM) injection: the main excretion route is via blood, not bile. Research Communications in Molecular Pathology & Pharmacology, 1994, 85: 217-226.
21. Suttle N.F., Field A.G.: Effects of dietary supplements of thiomolybdates on copper and molybdenum metabolism in sheep. J. Comp. Pathol. 1983, 93: 379-389.
22. Thaler H.: Der Morbus Wilson (hepatolenticuläre Degeneration). In: Leberkrankheiten. Springer-Verlag, Berlin, 1982, 243-247.
23. Tontis A., König H., Luginbühl H.: Zur Pathologie der chronischen Kupfervergiftung beim Schaf: Beobachtungen an 14 Spontanfällen. Schweiz. Arch. Tierheilk. 1980, 122: 107-116.