Preparation and biological activities of a bivalent poly(ethylene glycol) hybrid containing an active site and its synergistic site of fibronectin

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 9, 2002, Pages 1229-1232

  Susuki, Yuichi ^a   Hojo, Keiko ^a   Okazaki, Ikuko ^b   Kamata, Haruhiko ^c   Sasaki, Masahiko ^a   Maeda, Mitsuko ^a   Nomizu, Motoyoshi ^b   Yamamoto, Yoko ^c   Nakagawa, Shinsaku ^c   Mayumi, Tadanori ^c   Kawasaki, Koichi ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Anti metastatic activity; Fibronectin; Hybrid; Poly(ethylene glycol); Spreading activity

Indexed keywords

AMINO ACID; AMINO ACID DERIVATIVE; ARGINYLGLYCYLASPARTIC ACID; ARGINYLGLYCYLASPARTYL AMINO ACID TYPE MACROGOL PROLYLHISTIDYLSERYLARGINYLASPARAGINE; FIBRONECTIN; HYBRID PROTEIN; MACROGOL; PROLYLHISTIDYLSERYLARGINYLASPARAGINE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; MACROGOL DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL ACTIVITY; CELL SPREADING; DRUG CONJUGATION; METASTASIS; MOUSE; NONHUMAN; ANIMAL; BINDING SITE; C57BL MOUSE; CANCER TRANSPLANTATION; CELL SURVIVAL; CHEMISTRY; EXPERIMENTAL MELANOMA; HAMSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PATHOLOGY; SYNTHESIS;

AMINO ACIDS; ANIMALS; ANTINEOPLASTIC AGENTS; BINDING SITES; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; FIBRONECTINS; INDICATORS AND REAGENTS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; POLYETHYLENE GLYCOLS;

EID: 19044386477     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.1229     Document Type: Article

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