Neuroendocrine and renal effects of inorganic lead;Effetti neuroendocrini e renali del piombo inorganico

Giornale Italiano di Medicina del Lavoro ed Ergonomia

Volumn 27, Issue 1 SUPPL., 2005, Pages 33-38

  Alinovi, R ^a   Scotti, E ^a   Andreoli, R ^a   De Palma, G ^a   Goldoni, M ^a   Apostoli, P ^b   Mutti, Antonio ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

ALAD polymorphism; Kidney; Lead; Neuroendocrine system

Indexed keywords

LEAD; PLASMA PROTEIN; PROLACTIN;

ADULT; AGED; CONCENTRATION RESPONSE; CONFERENCE PAPER; FEMALE; GENETIC POLYMORPHISM; HUMAN; KIDNEY FUNCTION; KIDNEY PARENCHYMA; LEAD BLOOD LEVEL; LEAD POISONING; MAJOR CLINICAL STUDY; MALE; NEUROENDOCRINE SYSTEM; OCCUPATIONAL EXPOSURE; PREVALENCE; THERMOSTABILITY; URINARY EXCRETION;

ADULT; AGED; HUMANS; KIDNEY; LEAD; MIDDLE AGED; NEUROSECRETORY SYSTEMS; OCCUPATIONAL EXPOSURE; PORPHOBILINOGEN SYNTHASE;

EID: 19044378175     PISSN: 15927830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (16)

1. Mutti A, Smargiassi A. Selective vulnerability of dopaminergic systems to industrial chemicals: risk assessment of related neuroendocrine changes. Toxicol Ind Health 1998; 14 (1-2): 311-323.
2. Khalil-Manesh F, Gonick HC, Cohen AH, Alinovi R, Bergamaschi E, Mutti A, Rosen VJ. Experimental model of lead nephropathy. I. Continuous high-dose lead administration. Kidney Int 1992; 41(5): 1192-1203.
3. Cardenas A, Roels H, Bernard AM, Barbon R, Buchet JP, Lauwerys RR et al. Markers of early renal changes induced by industrial pollutants. II Application to workers exposed to lead. Br J Ind Med 1993; 50(1): 28-36.
4. Fels LM, Herbort C, Pergande M, Jung K, Hotter G, Rosello J et al. Nephron target sites in chronic exposure to lead. Nephrol Dial Transplant 1994: 9: 1740-1746.
5. Roels HA, Hoet P, Lison D. Usefulness of biomarkers of exposure to inorganic mercury, lead, or cadmium in controlling occupational and environmental risks of nephrotoxicity. Renal Failure 1999: 21(3-4): 251-262.
6. Kelada SN, Shelton E, Kaufmann RB, Khoury MJ. δ-Aminolevulinic acid dehydratase genotype and lead toxicity: a HuGE review. Am J Epidemiol 2001; 154(1): 1-13.
7. Smith CM, Wang X, Hu H, Kelsey KT. A polymorphism in the δ-aminolevulinic acid dehydratase gene may modify the pharmacokinetics and toxicity of lead. Environ Health Perspect 1995; 103(3): 248-253.
8. Bergdahl IA, Gerhardsson L, Schutz A, Desnick RJ, Wetmur JG, Skerfving S. Delta-aminolevulinic acid dehydratase polymorphism: influence on lead levels and kidney function in humans. Arch Environ Health 1997; 52(2): 91-96.
9. Wu MT, Kelsey K, Schwartz J, Sparrow D, Weiss S, Hu H. A δ-aminolevulinic acid dehydratase (ALAD) polymorphism may modify the relationship of low-level lead exposure to uricemia and renal function: the normative aging study. Environ Health Perspect 2003; 111(3): 335-340.
10. Weaver VM, Shwartz BS, Ahn KD, Stewart WF, Kelsey KT, Todd AC et al., Association of renal function with polymorphisms in the δ-aminolevulinic acid dehydratase, vitamin D receptor and nitric oxide synthase genes in Korean lead workers. Environ Health Perspect 2003; 111(13): 1613-1619.
11. Mutti A, Alinovi R, Bergamaschi E, Biagini C, Cavazzini S, Franchini I et al. Nephropathies and exposure to perchloroethylene in dry-cleaners. Lancet 1992; 340: 189-193.
12. Mutti A, Lucertini S, Valcavi PP, Neri TM, Fornari M, Alinovi R, Franchini I. Urinary excretion of brush-border antigen revealed by monoclonal antibody: early indicator of toxic nephropathy. Lancet 1985, 2(8461): 914-917.
13. Chia KS, Mutti A, Tan C, Ong HY, Jeyaratnam J, Ong CN, Lee E. Urinary N-acetyl-beta-D-glucosaminidase activity in workers exposed to inorganic lead. Occup Environ Med 1994: 51(2): 125-129.
14. Petrucci R, Leonardi A, Battistuzzi G. The genetic polymorphism of delta-aminolevulinate dehydrase in Italy. Hum Genet 1982; 60(3): 289-290.
15. Alinovi R, Buzio L, Mozzoni P, De Palma G, Carta P, Flore C et al. Effetti renali di basse dosi di mercurio. Med Lav 2002; 93(3): 191-201.
16. Bellinger D, Hu H, Titlebaum L, Needleman HL. Attentional correlates of dentin and bone lead levels in adolescents. Arch Environ Health 1994; 49(2): 98-105. Antonio Mutti