Effect of the intestinal flora on amyloid deposition in a transgenic mouse model of familial amyloidotic polyneuropathy

Experimental Animals

Volumn 51, Issue 4, 2002, Pages 309-316

  Noguchi, Hiromitsu ^a,c   Ohta, Mika ^a   Wakasugi, Shoji ^c   Noguchi, Kazuhiro ^b   Nakamura, Naoko ^b   Nakamura, Osamu ^c   Miyakawa, Kazuhisa ^c   Takeya, Motohiro ^c   Suzuki, Misao ^b   Nakagata, Naomi ^b   Urano, Toru ^b   Ono, Tomomichi ^c   Yamamura, Ken Ichi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b Kumamoto University   (Japan)

^c KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Amyloid; Familial amyloidotic polyneuropathy; Intestinal flora

Indexed keywords

BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; MUS MUSCULUS; POSIBACTERIA;

AMYLOID;

ANIMAL; ARTICLE; DISEASE MODEL; FAMILIAL AMYLOID POLYNEUROPATHY; GERMFREE ANIMAL; METABOLISM; MICROBIOLOGY; MOUSE; STOMACH JUICE; TRANSGENIC MOUSE;

AMYLOID; AMYLOID NEUROPATHIES, FAMILIAL; ANIMALS; DISEASE MODELS, ANIMAL; GASTROINTESTINAL CONTENTS; MICE; MICE, TRANSGENIC; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 19044369245     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.51.309     Document Type: Article

References (25)

1. Yamamura, K., Wakasugi, S., Maeda, S., Inomoto, T., Iwanaga, T., Uehira, M., Araki, K., Miyazaki, J., and Shimada, K. 1987. Tissue-specific and developmental expression of human transthyretin gene in transgenic mice. Dev. Genet. 8: 195-205.
2. Wakasugi, S., Inomoto, T., Yi, S., Naito, M., Uehira, M., Iwanaga, T., Maeda, S., Araki, K., Miyazaki, J., Takahashi, K., Shimada, K., and Yamamura, K. 1987. A transgenic mouse model of familial amyloidotic polyneuropathy. Proc. Japan. Acad. 63: 344-347.
3. Nagata, Y., Tashiro, F., Yi, S., Murakami, T., Maeda, S., Takahashi, K., Shimada, K., Okamura, H., and Yamamura, K. 1995. A 6-Kb upstream region of the human transthyretin gene can direct developmental, tissue-specific, and quantitatively normal expression in transgenic mouse. J. Biochem. 117: 169-175.
4. Connors, L.H., Richardson, A.M., Thébrege, R., and Costello, C.E. 2000. Sequence communication; tabulation of transthyretin (TTR) variants as of 1/1/2000. Amyloid: Int. J. Exp. Clin. Invest. 7: 54-69.
5. Holmgren, G., Bergstöm, S., Drugge, U., Lundgren, E., Nording-Sikstöm, C., Sandgren, O., and Steen, L. 1992. Homozygosity for the transthyretin-Met30-gene in seven individuals with familial amyloidosis with polyneuropathy detected by restriction enzyme analysis of amplified genomic DNA sequences. Clin. Genet. 41: 39-41.
6. Nakazato, M., Shiomi, K., Miyazato, M., and Matsukura, S. 1992. Type I familial amyloidotic polyneuropathy in Japan. Internal. Med. 31: 1335-1338.
7. Sousa, A., Coelho, T., Barros, J., and Sequeiros, J. 1995. Genetic epidemiology of familial amyloidotic polyneuropathy (FAP)-type I in Póvoa do Varzim and Vila do Conde (North of Portugal). Am. J. Hum. Genet. 60: 512-521.
8. Holmgren, G., Costa, P.M.P., Andersson, C., Asplund, K., Steen, L., Beckman, L., Nylander, P.O., Teixeira, A., and Saraiva, M.J.M. 1994. Geographical distribution of TTR met30 carriers in northern Sweden: discrepancy between carrier frequency and prevalence rate. J. Med. Genet. 31: 351-354.
9. Holmgren, G., Ando, Y., Wikstöm, L., Rydh, A., and Suhr, O. 1997. Discordant symptoms in monozygotic twins with familial amyloidotic polyneuropathy (FAP) (TTR Met30). Amyloid 4: 178-180.
10. Takaoka, Y., Tashiro, F., Yi, S., Maeda, S., Takahashi, K., Sasaki, Y., and Yamamura, K. 1997. Comparison of amyloid deposition in two lines of transgenic mouse that model familial amyloidotic polyneuropathy, type I. Transgenic Res. 6: 261-269.
11. Nakagata, N. 1995. Studies on cryopreservation of embryos and gametes in mice. Exp. Anim. 44: 1-8.
12. Nakagata, N. 1996. Use of cryopreservation techniques of embryos and spermatozoa for production of transgenic (Tg) mice and for maintenance of Tg mouse lines. Lab. Anim. Sci. 46: 236-238.
13. Mitsuoka, T., Ohno, K., Benno, Y., Suzuki, K., and Namba, K. 1976. Die Faekalflora bei Menschen. IV. Mitteilung: Vergleich des neu entwickelten Verfahrens mit dem bisheringen üblichen Verfahren zur Darmfloraanalyse. Zbl. Bakt. Hyg., I. Abt. Orig. A 234: 219-233.
14. Mitsuoka, T., Sega, T., and Yamamoto, S. 1965. Eine verbesserte Methodik der qualitativen und quantitativen Analyse der Darmflora von Menschen und Tieren. Zbl. Bakt., I. Abt. Orig. 195: 455-169.
15. Itoh, K., Mitsuoka, T., Sudo, K., and Suzuki, K. 1983. Comparison of fecal flora of mice based upon different strains and different housing. Z. Versuchstierk. 25: 135-146.
16. Kanda, Y., Goodman, D.S., Canfield, R.E., and Morgan, F.J. 1974. The amino acid sequence of human plasma prealbumin. J. Biol. Chem. 249: 6796-6805.
17. Blake, C.C.F., Geisow, M.J., Oately, S.J., Rerat, B., and Rerat, C. 1978. Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement. J. Mol. Biol. 121: 339-356.
18. Colon, W., Lai, Z., McCutchen, S.L., Miroy, G.J., Strang, C., and Kelly, J.W. 1996. FAP mutations destabilize transthyretin facilitating conformational changes required for amyloid formation. Ciba. Found. Symp. 199: 228-238.
19. Colon, W. and Kelly, J.W. 1992. Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro. Biochem. 31: 8654-8660.
20. Kelly, J.W., Colon, W., Lai, Z., Lashuel, H.A., Mcculloch, J., McCutchen, S.L., Miroy, G.J., and Peterson, S.A. 1997. Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid. Adv. Protein Chem. 50: 161-181.
21. Itoh, K. and Freter, R. 1989. Control of Escherichia coli populations by a combination of indigenous clostridia and lactobacilli in gnotobiotic mice and continuous-flow cultures. Infect. Immun. 57: 559-565.
22. Diamond, R.D. 1995. Mechanisms involved in neutrophil-mediated killing of Candida albicans hyphae. Jpn. J. Med. Mycol. 36: 1-6.
23. Gresham, H.D., Lowrance, J.H., Caver, T.E., Wilson, B.S., Cheung, A.L., and Lindberg, F.P. 2000. Survival of Staphylococcus aureus inside neutrophils contributes to infection. J. Immunol. 164: 3713-3722.
24. Yamazaki, S., Ueda, K., and Someya, S. 1981. Non-immunological resistance of mice to infection with a virulent strain of Mycobacterium bovis. S. Sasaki (ed.), Advances in Germfree Research. pp. 419-423. Tokai Univ. Press, Tokyo.
25. Stone, P.J., Campistol, J.M., Abraham, C.R., Rodgers, O., Shirahama, T., and Skinner, M. 1993. Neutrophil proteases associated with amyloid fibrils. Biochem. Biophys. Res. Commun. 197: 130-136.