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Volumn 48, Issue 1, 2001, Pages 1-4

Synthetic studies of a didemnin B analog based on a 2,3-diamino sugar scaffolding

Author keywords

Bioactive conformation; Cyclodepsipeptide; Didemnin B; Molecular modeling; Sugar scaffolding

Indexed keywords


EID: 18944366847     PISSN: 00094536     EISSN: None     Source Type: Journal    
DOI: 10.1002/jccs.200100001     Document Type: Article
Times cited : (1)

References (12)
  • 5
    • 85037292530 scopus 로고    scopus 로고
    • note
    • Calculations were performed using MacroModel v3.1X on a Silicon Graphics Iris 4D/320S computer. Minimizations were generated using PRCG followed by FNMR with MM2 force field to obtain an overlay. RMS of carbonyl functionalities (1.687), amide hydrogens (1.293) and the side chain trajectories (1.412).
  • 10
    • 85037291908 scopus 로고    scopus 로고
    • note
    • 10Na: m/z 784.3785, found 784.3763.
  • 12
    • 0025036824 scopus 로고
    • Synthesis of methyl (S)-2-hydroxy-3-methylbutanoate and 2-[(tert-butyldimethylsilyl)oxy]-L-lactyl-L-proline methyl ester was reported in J. Am. Chem. Soc. 1990, 112, 21, 7659. Desilylation and hydrolysis of 2-[(tert-butyldimethylsilyl)oxy]-L-lactyl-L-proline methyl ester provided L-lactyl-L-proline.
    • (1990) J. Am. Chem. Soc. , vol.112 , Issue.21 , pp. 7659


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.