Effect of L-carnitine on erythroid colony formation on mouse bone marrow cells

Nephrology Dialysis Transplantation

Volumn 20, Issue 5, 2005, Pages 981-984

  Kitamura, Yukika ^a   Satoh, Kazunori ^a   Satoh, Takashi ^a   Takita, Manabu ^a   Matsuura, Akihiro ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

Anaemia; CFU E; Erythropoiesis; L carnitine; Mouse bone marrow cell; rhEPO

Indexed keywords

CARNITINE; METHYLCELLULOSE; RECOMBINANT ERYTHROPOIETIN;

ANEMIA; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BONE MARROW CELL; CELL COUNT; COLONY FORMATION; COLONY FORMING UNIT E; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CULTURE VESSEL; DRUG MECHANISM; ERYTHROBLAST; ERYTHROID CELL; ERYTHROPOIESIS; FEMALE; INCUBATION TIME; KIDNEY DISEASE; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BONE MARROW CELLS; CARNITINE; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; ERYTHROPOIETIN, RECOMBINANT; FEMALE; MICE;

EID: 18944364431     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/gfh758     Document Type: Article

References (15)

1. Evans A. Dialysis-related carnitine disorder and levocarnitine pharmacology. Am J Kidney Dis 2003; 41: S13-S26
2. Goral S. Levocarnitine's role in the treatment of patients with end-stage renal disease: a review. Dial Transplant 2001; 30: 530-539
3. Bommer J. Saving erythropoietin by administering L-carnitine? Nephrol Dial Transplant 1999; 14: 2819-2821
4. Golper TA, Goral S, Becker BN, Langman CB. L-Carnitine treatment of anemia. Am J Kidney Dis 2003; 41: S27-S34
5. Azzadin A, Wollny T, Pawlak R et al. L-Carnitine effects on anemia in uremic rats treated with erythropoietin. Nephron 1999; 83: 370-371
6. Arduini A, Rossi M, Mancinelli G et al. Effect of L-carnitine and acetyl-L-carnitine on the human erythrocyte membrane stability and deformability. Life Sci 1990; 47: 2395-2400
7. Labonia WD, Morelli OH Jr, Gimenez MI, Freuler PV, Morelli OH. Effect of L-carnitine on sodium transport in erythrocytes from dialyzed uremic patients. Kidney Int 1987; 32: 754-759
8. de los Reyes B, Navarro JA, Perez-Garcia R et al. Effects of L-carnitine on erythrocyte acyl-CoA, free-CoA, and glycero-phospholipid acyltransferase in uremia. Am J Clin Nutr 1998; 67: 386-390
9. Matsumura M, Hatakeyama S, Koni I, Mabuchi H. Effect of L-carnitine and palmitoyl-L-carnitine on erythroid colony formation in fetal mouse liver cell culture. Am J Nephrol 1998; 18: 355-358
10. Iscove NN, Sieber F. Erythroid progenitors in mouse bone marrow detected by macroscopic colony formation in culture. Exp Hematol 1975; 3: 32-43
11. Iscove NN, Sieber F, Winterhalter KH. Erythroid colony formation in cultures of mouse and human bone marrow: analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-concanvalin. Am J Cell Physiol 1974; 83: 309-320
12. Wanner C, Wackerle B, Boeckle H, Schollmeyer P, Horl WH. Plasma and red blood cell carnitine and carnitine esters during L-carnitine therapy in hemodialysis patients. Am J Clin Nutr 1990; 51: 407-410
13. Jeulin C, Lewin L-M. Role of free L-carnitine and acetyl-L-carnitine in post-gonadal maturation of mammalian spermatozoa. Hum Reprod Update 1996; 2: 87-102
14. Mutomba MC, Yuan H, Konyavko M et al. Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine. FEBS Lett 2000; 478: 19-25
15. Ishii T, Shimpo Y, Matsuoka Y, Kinoshita K. Anti-apoptotic effect of acetyl-L-carnitine and L-carnitine in primary cultured neurons. Jpn J Pharmacol 2000; 83: 119-124