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For applications in the synthesis of natural products: (a) Harrington, P. J. Transition Metals in Total Synthesis; Wiley: New York, 1990; p 346. For recent examples: (b) Dötz, K. H.; Neuss, O.; Nieger, M. Synlett 1996, 995. (c) Pulley, S. R.; Carey, J. P. J. Org. Chem. 1998, 63, 5275. (d) Harrity, J. P. A.; Kerr, W. J.; Middlemiss, D.; Scott, J. S. J. Organomet. Chem. 1997, 532, 219.
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For applications in the synthesis of natural products: (a) Harrington, P. J. Transition Metals in Total Synthesis; Wiley: New York, 1990; p 346. For recent examples: (b) Dötz, K. H.; Neuss, O.; Nieger, M. Synlett 1996, 995. (c) Pulley, S. R.; Carey, J. P. J. Org. Chem. 1998, 63, 5275. (d) Harrity, J. P. A.; Kerr, W. J.; Middlemiss, D.; Scott, J. S. J. Organomet. Chem. 1997, 532, 219.
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For the benzannulation reaction of carbohydrate-modified metal carbenes: (a)
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For the benzannulation reaction of carbohydrate-modified metal carbenes: (a) Dötz, K. H.; Ehlenz, R. Chem. Eur. J. 1997, 3, 1751. (b) Hallet, M. R.; Painter, J. E.; Quayle, P.; Ricketts, D.; Patel, P. Tetrahedron Lett. 1998, 39, 2851.
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For the benzannulation reaction of carbohydrate-modified metal carbenes: (a) Dötz, K. H.; Ehlenz, R. Chem. Eur. J. 1997, 3, 1751. (b) Hallet, M. R.; Painter, J. E.; Quayle, P.; Ricketts, D.; Patel, P. Tetrahedron Lett. 1998, 39, 2851.
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(b) For a closely related reaction: Herndon, J. W.; Wang, H. J. Org. Chem. 1998, 63, 4562.
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In the case of β-amino-α,β-unsaturated Fischer carbene complexes the cyclopentannulation reaction becomes the major or exclusive reaction pathway: (a)
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In the case of β-amino-α,β-unsaturated Fischer carbene complexes the cyclopentannulation reaction becomes the major or exclusive reaction pathway: (a) de Meijere, A. Pure Appl. Chem. 1996, 68, 61. (b) Aumann, R.; Nienaber, H. Adv. Organomet. Chem. 1997, 41, 163. (c) For an unexpected coupling involving three molecules of alkyne: Schirmer, H.; Duetsch, M.; Stein, F.; Labahn, T.; Knieriem, B.; de Meijere, A. Angew. Chem., Int. Ed. Engl. 1999, 38, 1285.
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In the case of β-amino-α,β-unsaturated Fischer carbene complexes the cyclopentannulation reaction becomes the major or exclusive reaction pathway: (a) de Meijere, A. Pure Appl. Chem. 1996, 68, 61. (b) Aumann, R.; Nienaber, H. Adv. Organomet. Chem. 1997, 41, 163. (c) For an unexpected coupling involving three molecules of alkyne: Schirmer, H.; Duetsch, M.; Stein, F.; Labahn, T.; Knieriem, B.; de Meijere, A. Angew. Chem., Int. Ed. Engl. 1999, 38, 1285.
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(c) For an unexpected coupling involving three molecules of alkyne
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In the case of β-amino-α,β-unsaturated Fischer carbene complexes the cyclopentannulation reaction becomes the major or exclusive reaction pathway: (a) de Meijere, A. Pure Appl. Chem. 1996, 68, 61. (b) Aumann, R.; Nienaber, H. Adv. Organomet. Chem. 1997, 41, 163. (c) For an unexpected coupling involving three molecules of alkyne: Schirmer, H.; Duetsch, M.; Stein, F.; Labahn, T.; Knieriem, B.; de Meijere, A. Angew. Chem., Int. Ed. Engl. 1999, 38, 1285.
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41
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Dötz and Hegedus noted earlier that the use of electronically deactivated amino carbene complexes, like N-acyl and pyrryl derivatives, increases the benzannulation-to-cyclopentannulation ratio: (a)
-
Dötz and Hegedus noted earlier that the use of electronically deactivated amino carbene complexes, like N-acyl and pyrryl derivatives, increases the benzannulation-to-cyclopentannulation ratio: (a) Grotjahn, D. B.; Kroll, F. E. K.; Schäfer, T.; Harms, K.; Dötz, K. H. Organometallics 1992, 11, 298. (b) Merino, I.; Hegedus, L. S. Organometallics 1995, 14, 2522.
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Dötz and Hegedus noted earlier that the use of electronically deactivated amino carbene complexes, like N-acyl and pyrryl derivatives, increases the benzannulation-to-cyclopentannulation ratio: (a) Grotjahn, D. B.; Kroll, F. E. K.; Schäfer, T.; Harms, K.; Dötz, K. H. Organometallics 1992, 11, 298. (b) Merino, I.; Hegedus, L. S. Organometallics 1995, 14, 2522.
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0041523185
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The preparation and the benzannulation reaction of some electron-poor aryl Fischer carbene complexes have been advanced Abstracts of Papers New Orleans, LA, August ORG 590
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The preparation and the benzannulation reaction of some electron-poor aryl Fischer carbene complexes have been advanced: Liptak, V. P.; Wulff, W. D. Abstracts of Papers, 218th National Meeting of the American Chemical Society, New Orleans, LA, August 1999; ORG 590.
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53
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Preliminary communication
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Preliminary communication: Barluenga, J.; López, L. A.; Martínez, S.; Tomás, M. J. Org. Chem. 1998, 63, 7588.
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0342737497
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The tungsten carbene complex (E)-6 did not react with 1-pentyne (5 equiv.) after 48 h in refluxing THF
-
The tungsten carbene complex (E)-6 did not react with 1-pentyne (5 equiv.) after 48 h in refluxing THF.
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57
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0000123442
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(a) The reaction of alkenyl(methoxy)carbene complexes with terminal, electron-poor alkynes furnishes benzannulation products in <22%
-
(a) The reaction of alkenyl(methoxy)carbene complexes with terminal, electron-poor alkynes furnishes benzannulation products in <22%: Wulff, W. D.; Chan, K.-S.; Tang, P.-C. J. Org. Chem. 1984, 49, 2293.
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Wulff, W.D.1
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0342737498
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(b) Internal, electron-poor alkynes and alkenyl(methoxy)carbene complexes have been reported to give variable mixtures of phenol and lactone products: Refs. 9e,19
-
(b) Internal, electron-poor alkynes and alkenyl(methoxy)carbene complexes have been reported to give variable mixtures of phenol and lactone products: Refs. 9e,19.
-
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59
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0027316022
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For the preparation of protected hydroquinone chromium(tricarbonyl)complexes from alkenyl(alkoxy)carbene complexes
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For the preparation of protected hydroquinone chromium(tricarbonyl)complexes from alkenyl(alkoxy)carbene complexes: Chamberlin, S.; Wulff, W. D.; Bax, B. Tetrahedron 1993, 49, 5531.
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60
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0342737496
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13C-H correlations (HMQC y HMBC experiments)
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13C-H correlations (HMQC y HMBC experiments).
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