Design and synthesis of cyclic inhibitors of matrix metalloproteinases and TNF-alpha production.

Journal of medicinal chemistry

Volumn 41, Issue 11, 1998, Pages 1745-1748

  Xue, C B ^a   He, X ^a   Roderick, J ^a   DeGrado, W F ^a   Cherney, R J ^a   Hardman, K D ^a   Nelson, D J ^a   Copeland, R A ^a   Jaffee, B D ^a   Decicco, C P ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; GELATINASE B; HYDROXAMIC ACID; INTERSTITIAL COLLAGENASE; LACTAM; LIPOPOLYSACCHARIDE; METALLOPROTEINASE; PROTEINASE INHIBITOR; SC 903; SE 205; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

COLLAGENASES; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROXAMIC ACIDS; LACTAMS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; PROTEASE INHIBITORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 18844466185     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970849z     Document Type: Article

References (0)