The effect of fenofibrate treatment on endothelium-dependent relaxation induced by oxidative modified low density lipoprotein from hyperlipidemic patients

Molecular and Cellular Biochemistry

Volumn 207, Issue 1-2, 2000, Pages 123-129

  Liang, Binhua ^a   McMaster, Jason C ^a   Kroeger, Edwin A ^a   Hatch, Grant M ^a   Mymin, David ^a   Dembinski, Tom ^a   Arthur, Gilbert ^a   Shen, Garry ^a   Man, Ricky Y K ^a   Choy, Patrick C ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Fenofibrate; Hyperlipidemia; Low density lipoprotein; Lysophosphatidylcholine

Indexed keywords

CHOLESTEROL; FENOFIBRATE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN;

ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DIET THERAPY; DRUG EFFICACY; HUMAN; HYPERLIPIDEMIA; LIPOPROTEIN METABOLISM; NONHUMAN; RAT; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALIA;

EID: 18844465975     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1007019019911     Document Type: Article

References (28)

1. Brown MS, Goldstein JL: Receptor-mediated control of cholesterol metabolism. Science 191: 150-154, 1976
2. Farmer JA, Gotto AM Jr: Risk factors for coronary artery disease. In: E. Braunwald (ed). Heart Disease (4th edn). WB Saunders, Philadelphia, PA, USA, 1991, pp 1125-1160
3. Drexler M, Zeiher AM: Endothelial function in human coronary arteries in vivo. Focus on hypercholesterolemia. Hypertension 18: 1190-1199, 1991
4. Luscher TF, Tanner FC, Noll G: Lipids and endothelial function: Effects of lipid-lowering and other therapeutic interventions. Curr Opin Lipidol 7: 234-240, 1996
5. Winzerling JJ, Jouni Z, McNamara DJ: Lipoprotein metabolism in human peritoneal cells. Life Sci 58: 1631-1641, 1996
6. Luoma J, Hiltunen T, Sarkioja T, Moestrup SK, Gliemann J, Kodama T, Nikkan T, Yha Herttuala S: J Clin Invest 93: 2014-2021, 1994
7. Goldstein JL, Ho YK, Basu SK, Brown MS: Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein producing massive cholesterol deposition. Proc Natl Acad Sci USA 76: 333-337, 1979
8. Verlangieri AJ, Buxh MJ: Effect of d-alpha tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr 11: 131-138, 1992
9. Heinecke JW, Rosen H, Chait A: Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture. J Clin Invest 74: 1890-1894, 1984
10. Henriksen T, Mahoney EM, Steinberg D: Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptor for acetylated low density lipoprotein. Proc Natl Acad Sci USA 78: 6499-6503, 1981
11. Heinecke JW, Baker H, Rosen H, Chait A: Superoxide mediated modification of low density lipoprotein by human arterial smooth muscle cells. J Clin Invest 77: 757-761, 1986
12. Cathcart MK, Morel DW, Chisolm GM: Monocytes and neutrophils oxidize low density lipoprotein making it cytotoxic. J Leuco Biol 38: 341-350, 1985
13. Maziere C, Auclair M, Roserober F, Leflou P, Maziere JC: FEBS Lett 363: 277-279, 1995
14. Yla-Herttuala S, Palinski W, Rosenfield ME, Parthasarathy S, Carew TE, Butler S, Witztum JL, Steinberg D: Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbits and man. J Clin Invest 84: 1086-1095, 1989
15. Palinski W, Yla-Herttuala S, Rosenfeld ME, Butler SW, Socher SA, Parthasarathy S, Curtiss LK, Witztum JL: Antisera and monoclonal antibodies specific for epitodes generated during oxidative modification of low density lipoprotein. Atherosclerosis 10: 325-335, 1990
16. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum, JL: Beyond cholesterol, modifications of low density lipoprotein that increase its atherosclerogenicity. N Engl J Med 320: 915-924, 1989
17. Liu SY, Lu X, Choy S, Dembinski TC, Hatch GM, Mymin D, Shen X, Angel A, Choy PC, Man RYK: Alteration of lysophosphatidylcholine content in low density lipoprotein after oxidative modification: Relationship to endothelium dependent relaxation. Cardiovasc Res 28: 1476-1481, 1994
18. Chen L, Liang BH, Froese DE, Liu SY, Wong JT, Tran K, Hatch GM, Mymin D, Kroeger EA, Man, RYK, Choy PC: J Lipid Res 38: 546-553, 1997
19. Caslake MJ, Packard CT, Gaw A, Murray E, Griffin BA, Vallance BD, Sheperd J: Fenofibrate and low density lipoprotein metabolic heterogeneity in hypercholesterolemia. Atheroscler Thromb 13: 702-711, 1993
20. Brown WV, Dujorne CW, Farguahar JW, Feldman EB, Grundy SM, Knopp RH, Lasser NL, Mellies MJ, Palmer RH, Samuel P, Schonfeld G, Superko R: Effects of fenofibrate on plasma lipids. Double-blind, multicenter study in patients with type IIa or lib hyperlipidemia. Atherosclerosis 6: 670-678, 1986
21. Goldberg AC, Schonfeld G, Feldman EB, Ginsberg HN, Hunninghak DB, Insull WRJ, Knopp RH, Kwiterovich PO, Mellies MJ, Pickering J, Samuel P: Fenofibrate for the treatment of type IV and V hyperlipoproteinemias: A double-blind, placebo-controlled multicenter US study. Clin Ther 11: 69-83, 1989
22. Friedewald WT, Levy RI, Frederickson DS: Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 18: 499-502, 1972
23. Lowry, OH, Roseborough NJ, Farr AL, Randall RJ: Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275, 1951
24. Bartlett, GR: Phosphorus assay in column chromatography. J Biol Chem 234: 466-468, 1959
25. Tardi PG, Mukherjee JJ, Choy PC: The quantitation of long chain acyl-coa in mammalian tissues. Lipids 27: 65-67, 1992
26. Kugiyama K, Kerns SA, Morrisett JD, Robert R, Henry PD: Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low density lipoprotein. Nature 344: 160-162, 1990
27. Rosenfeld ME: Oxidized LDL affects multiple atherogenic cellular responses. Circulation 83: 2127-2140, 1991
28. Andrews B, Burnaud K, Pagana G, Browse N, Rice-Evans C, Sommerville K, Leake D, Taub N: Oxidisability of low density lipoprotein in patient with carotid or femoral artery atherosclerosis. Atherosclerosis 12: 78-84, 1995