Profiling the subjective, psychomotor, and physiological effects of a hydrocodone/acetaminophen product in recreational drug users

Drug and Alcohol Dependence

Volumn 78, Issue 3, 2005, Pages 243-252

  Zacny, James P ^a   Gutierrez, Sandra ^a   Bolbolan, Shahla A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Abuse liability; Human; Hydrocodone; Opioid; Prescription; Subjective

Indexed keywords

HYDROCODONE; HYDROCODONE BITARTRATE PLUS PARACETAMOL; MORPHINE; MORPHINE SULFATE; MU OPIATE RECEPTOR; NORCO; PARACETAMOL; PERCOCET; PLACEBO; RECREATIONAL DRUG; ZYDONE;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG ABUSE; DRUG EFFECT; DRUG MEGADOSE; DRUG USE; FEMALE; HUMAN; MALE; MEDICAL ASSESSMENT; MEDICAL LITERATURE; PHYSIOLOGY; PRESCRIPTION; PRIORITY JOURNAL; PSYCHOMOTOR PERFORMANCE; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANALGESICS, OPIOID; COGNITION DISORDERS; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; OXYCODONE; PSYCHOMOTOR DISORDERS; REACTION TIME; STREET DRUGS; SUBSTANCE-RELATED DISORDERS;

EID: 18844420034     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2004.11.009     Document Type: Article

References (34)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders-IV 1994 American Psychiatric Association Washington, DC, USA
2. A.D. Baddeley A three-minute reasoning test based on grammatical transformation Psychonom. Sci. 10 1968 341 342
3. W.T. Beaver, and D. McMillan Methodology considerations in the evaluation of analgesic combinations: acetaminophen (paracetamol) and hydrocodone in postpartum pain Br. J. Clin. Pharmacol. 10 1980 215S 223S
4. J.H. Brown, and P. Taylor Muscarinic receptor agonists and antagonists J.G. Hardman A.G. Gilman L.E. Limbird Goodman and Gilman's The Pharmacological Basis of Therapeutics ninth ed. 1996 Pergamon Press New York, USA 141 160
5. J.O. Cole, M.H. Orzack, B. Beake, M. Bird, and Y. Bat-tal Assessment of the abuse liability of buspirone in recreational drug users J. Clin. Psychiatry 43 1982 69 75
6. R.M. Craft Sex differences in opioid analgesia: "from mouse to man" Clin. J. Pain 19 2003 175 186
7. N.R. Eade, and L. Lasagna A comparison of acetophenetidin and acetaminophen. II. Subjective effects in healthy volunteers J. Pharmacol. Exp. Ther. 155 1967 301 308
8. N.B. Eddy, H. Halbach, and O.J. Braenden Synthetic substances with morphine-like effect. Clinical experience: potency, side-effects, addiction liability Bull. World Health Org. 17 1957 569 863
9. H.F. Fraser, and H. Isbell Addiction liabilities of morphinan, 6-methyldihydromorphine and dihydrocodeinone J. Pharmacol. Exp. Ther. 100 1950 128 135
10. H.F. Fraser, G.D. van Horn, W.R. Martin, A.B. Wolbach, and H. Isbell Methods for evaluating addiction liability. (a) "Attitude" of opiate addicts toward opiate-like drugs, (b) a short-term "direct" addiction test J. Pharmacol. Exp. Ther. 133 1961 371 387
11. R.R. Griffiths, G.E. Bigelow, and N.A. Ator Principles of initial experimental drug abuse liability assessment in humans Drug Alcohol Depend. 70 2003 S41 S54
12. C.A. Haertzen Development of scales based on patterns of drug effects, using the addiction research center inventory (ARCI) Psychol. Rep. 18 1966 163 194
13. J.G. Hannington-Kiff Measurement of recovery from outpatient general anaesthesia with a simple ocular test Br. Med. J. 3 1970 132 135
14. J.H. Hopkinson Hydrocodone - a unique challenge for an established drug: comparison of repeated oral doses of hydrocodone (10 mg) and codeine (60 mg) in the treatment of postpartum pain Curr. Res. Ther. 24 1978 503 516
15. D.R. Jasinski, and W.R. Martin Assessment of the dependence-producing properties of dihydrocodeinone and codoxime Clin. Pharmacol. Ther. 8 1967 266 270
16. L.D. Johnston, P.M. O'Malley, and J.G. Bachman Monitoring the Future National Results on Adolescent Drug Use: Overview of Key Findings, 2003 2004 National Institute on Drug Abuse Bethesda, MD, USA (NIH Publication No. 04-5506)
17. H.L. Kaplan, U.E. Busto, G.J. Baylon, S.W. Cheung, S.V. Otton, G. Somer, and E.M. Sellers Inhibition of cytochrome P450 2D6 metabolism of hydrocodone to hydromorphone does not importantly affect abuse liability J. Pharmacol. Exp. Ther. 281 1997 103 108
18. B. Kest, E. Sarton, and A. Dahan Gender differences in opioid-mediated analgesia: animal and human studies Anesthesiology 93 2000 539 547
19. Kleber, H.D., 1989. Drug abuse liability testing: human subject issues. In: Fischman, M.W., Mello, N.K. (Eds.), Testing for Abuse Liability of Drugs in Humans. NIDA Research Monograph Series No. 92. Rockville, MD, USA, DHHS Publication Number (ADM) 99-1613, pp. 341-356.
20. W.R. Martin, J.W. Sloan, J.D. Sapira, and D.R. Jasinski Physiologic, subjective and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man Clin. Pharmacol. Ther. 12 1971 245 258
21. H. McQuay Opioids in pain management Lancet 353 1999 2229 2232
22. E.J. Nuotto, and K. Korttila Evaluation of a new computerized psychomotor test battery: effects of alcohol Pharmacol. Toxicol. 68 1991 360 365
23. N.M. Petry, W.K. Bickel, J. Huddleston, E. Tzanis, and G.J. Badger A comparison of subjective, psychomotor, and physiological effects of a novel muscarinic analgesic, LY297802 tartrate, and oral morphine in occasional drug users Drug Alcohol Depend. 50 1998 129 136
24. K.L. Preston, G.E. Bigelow, W.K. Bickel, and I.A. Liebson Drug discrimination in human postaddicts: Agonist-antagonist opioids J Pharmacol Exp Ther 250 1989 184 196
25. T. Reisine, and G. Pasternak Opioid analgesics and antagonists J.G. Hardman A.G. Gilman L.E. Limbird Goodman and Gilman's The Pharmacological Basis of Therapeutics ninth ed. 1996 Pergamon Press New York 521 555
26. Substance Abuse and Mental Health Services Administration (SAMHSA), 2004. Office of Applied Studies, Results from the 2003 National Survey on Drug Use and Health: National Findings. Office of Applied Studies, NHSDA Series H-25. Rockville, MD, USA, DHHS Publication No. SMA 04-3964.
27. D. Wechsler The Measurement and Appraisal of Adult Intelligence 1958 Williams and Wilkins Baltimore, MD, USA
28. A. Wetherell Performance tests Environ. Health Perspect. 104 Suppl. 2 1996 247 273
29. C.J. Woolf, and M. Hashmi Use and abuse of opioid analgesics: potential methods to prevent and deter non-medical consumption of prescription opioids Curr. Opin. Investig. Drugs 5 2004 61 66
30. The top 200 prescriptions for 2003 by number of US prescriptions dispensed (accessed November 10, 2004) www.rxlist.com/top200.htm.
31. ®) in non-drug-abusing volunteers Psychopharmacology 165 2003 146 156
32. J.P. Zacny, and S. Gutierrez Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non-drug-abusing volunteers Psychopharmacology 170 2003 242 254
33. J. Zacny, G. Bigelow, P. Compton, K. Foley, M. Iguchi, and C. Sannerud College on problems of drug dependence taskforce on prescription opioid non-medical use and abuse: position statement Drug Alcohol Depend. 69 2003 215 232
34. J.P. Zacny, and R.E. Goldman Characterizing the subjective, psychomotor, and physiological effects of oral propoxyphene in non-drug-abusers Drug Alcohol Depend. 73 2004 133 140