Vascular involvement in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes

American Journal of the Medical Sciences

Volumn 329, Issue 5, 2005, Pages 265-266

  Takahashi, Nobuyuki ^a   Shimada, Toshio ^a   Murakami, Yo ^a   Katoh, Harumi ^a   Oyake, Nobuyuki ^a   Ishibashi, Yutaka ^a   Nishino, Ichizo ^b   Nonaka, Ikuya ^b   Goto, Yu Ichi ^b  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Hepatocyte growth factor; MELAS; Pulse wave contour analysis; Vascular involvement

Indexed keywords

SCATTER FACTOR; SUCCINATE DEHYDROGENASE;

ADULT; ARTICLE; BLOOD VESSEL COMPLIANCE; CASE REPORT; HOSPITAL ADMISSION; HUMAN; MALE; MELAS SYNDROME; MUSCLE BIOPSY; OSCILLATION; PULSE WAVE; VASCULAR DISEASE;

EID: 18844415552     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000441-200505000-00008     Document Type: Article

References (12)

1. Pavlakis SG, Phillips PC, Dimauro S, et al. Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes: a distinctive clinical syndrome. Ann Neurol 1984;16:481-8.
2. Ohama E, Ohama S, Ikuta F, et al. Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalopathy. Acta Neuropathol 1987;74:226-33.
3. Sakuta R, Nonaka I. Vascular involvement in mitochondrial myopathy. Ann Neurol 1989;25:594-601.
4. Goto Y, Nonaka I, Horai S. A mutation in the tRNAL-eu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature 1990;348:651-3.
5. Hasegawa H, Matsuoka T, Goto Y, et al. Strongly succinate dehydrogenase-reactive blood vessels in muscles from patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. Ann Neurol 1991;29:601-5.
6. Cohn J, Finkelstein S, McVeigh G, et al. Noninvasive pulse wave analysis for the early detection of vascular disease. Hypertension 1995;26:503-8.
7. Nakamura S, Moriguchi A, Morishita R, et al. A novel vascular modulator, hepatocyte growth factor (HGF), as a potential index of the severity of hypertension. Biochem Biophys Res Com 1998;242:238-43.
8. Morishita R, Nakamura S, Hayashi S, et al. Contribution of a vascular modulator, hepatocyte growth factor (HGF), to the pathogenesis of cardiovascular disease. J Atheroscler Thromb 1998;4:128-34.
9. Boros P, Miller C. Hepatocyte growth factor: a multifunctional cytokine. Lancet 1995;345:293-5.
10. Panza JA, Quyyumi AA, Brush JE Jr, et al. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990;323:22-7.
11. McVeigh G, Brennan G, Hayes R, et al. Vascular abnormalities in non-insulin-dependent diabetes mellitus identified by arterial waveform analysis. Am J Med 1993;95:424-30.
12. Morishita R, Nakamura S, Nakamura Y, et al. Potential role of an endothelium-specific growth factor, hepatocyte growth factor, on endothelial damage in diabetes. Diabetes 1997;46:138-42.