Mefloquine resistance reversal action of ketoconazole - A cytochrome P 450 inhibitor, against mefloquine-resistant malaria

Parasitology

Volumn 130, Issue 5, 2005, Pages 475-479

  Tripathi, R ^a   Awasthi, A ^b   Dutta, G P ^c  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b UNIVERSITY OF ALBERTA   (Canada)

^c NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Ketoconazole; Mefloquine resistance reversal; Multidrug resistant malaria; Plasmodium knowlesi

Indexed keywords

CHLOROQUINE; CYTOCHROME P450 3A; CYTOCHROME P450 3A INHIBITOR; INTERFERON; KETOCONAZOLE; MEFLOQUINE; QUININE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; BIOTRANSFORMATION; COMBINATION CHEMOTHERAPY; DOSE TIME EFFECT RELATION; ENZYME INHIBITION; HUMAN; LIVER MICROSOME; MALARIA; MALARIA CONTROL; MONKEY; MULTIDRUG RESISTANCE; NONHUMAN; PLASMODIUM KNOWLESI; PRIORITY JOURNAL; RHESUS MONKEY;

ANIMALS; ANTIMALARIALS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; KETOCONAZOLE; MACACA MULATTA; MALARIA; MEFLOQUINE; PLASMODIUM KNOWLESI;

MACACA MULATTA; PLASMODIUM KNOWLESI;

EID: 18844410085     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0031182004006481     Document Type: Article

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