Purification of a 75 kDa protein from the organelle matrix of human neutrophils and identification as N-acetylglucosamine-6-sulphatase

Biochemical Journal

Volumn 387, Issue 3, 2005, Pages 841-847

  Xu, Shengyuan ^a   Zhao, Linshu ^a   Larsson, Anders ^a   Smeds, Emanuel ^a   Kusche Gullberg, Marion ^a,b   Venge, Per ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Granule; N acetylglucosamine 6 sulphatase; Neutrophil; O desulphation; Organelle matrix; Release

Indexed keywords

BIOLOGICAL ORGANS; CELLS; CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETRY; PURIFICATION;

CHROMATOFOCUSING; EXTRACELLULAR MATRIX; NEUTROPHILS; ORGANELLE MATRIX;

PROTEINS;

CARBOHYDRATE; HEPARAN SULFATE; N ACETYLGLUCOSAMINE 6 SULFATASE; PHORBOL 13 ACETATE 12 MYRISTATE; SEPHADEX; SULFATASE; UNCLASSIFIED DRUG;

ARTICLE; CELL FRACTIONATION; CELL ORGANELLE; CELL SURFACE; CHROMATOFOCUSING; CHROMATOGRAPHY; DESULFURIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME RELEASE; ENZYME SUBSTRATE COMPLEX; EXTRACELLULAR MATRIX; GRANULOCYTE; HUMAN; HUMAN CELL; ION EXCHANGE CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NEUTROPHIL; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; SEQUENCE ANALYSIS;

HUMANS; NEUTROPHILS; ORGANELLES; SUBSTRATE SPECIFICITY; SULFATASES;

EID: 18844409602     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041811     Document Type: Article

References (35)

1. Burg, N. D. and Pillinger, M. H. (2001) The neutrophil: function and regulation in innate and humoral immunity. Clin. Immunol. 99, 7-17
2. Borregaard, N. and Cowland, J. B. (1997) Granules of the human neutrophilic polymorphonuclear leukocyte. Blood 89, 3503-3521
3. Borregaard, N., Sehested, M., Nielsen, B. S., Sengelov, H. and Kjeldsen, L. (1995) Biosynthesis of granule proteins in normal human bone marrow cells. Gelatinase is a marker of terminal neutrophil differentiation. Blood 85, 812-817
4. Sengelöv, H., Kjeldsen, L. and Borregaard, N. (1993) Control of exocytosis in early neutrophil activation. J. Immunol. 150, 1535-1543
5. Sengelov, H., Follin, P., Kjeldsen, L., Lollike, K., Dahlgren, C. and Borregaard, N. (1995) Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils. J. Immunol. 154, 4157-4165
6. Borregaard, N., Kjeldsen, L., Lollike, K. and Sengelov, H. (1993) Granules and vesicles of human neutrophils. The role of endomembranes as source of plasma membrane proteins. Eur. J. Haematol. 51, 318-322
7. Delclaux, C., Delacourt, C., D'Ortho, M. P., Boyer, V., Lafuma, C. and Harf, A. (1996) Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membrane. Am. J. Respir. Cell Mol. Biol. 14, 288-295
8. Basner, R., Kresse, H. and von Figura, K. (1979) N-Acetylglucosamine-6- sulfate sulfatase from human urine. J. Biol Chem. 254, 1151-1158
9. Freeman, C., Clements, P. R. and Hopwood, J. J. (1987) Human liver N-acetylglucosamine-6-sulphate sulphatase. Purification and characterization. Biochem. J. 246, 347-354
10. Kresse, H., Paschke, E., von Figura, K., Gilberg, W. and Fuchs, W. (1980) Sanfilippo disease type D: deficiency of N-acetylglucosamine-6-sulfate sulfatase required for heparan sulfate degradation. Proc. Natl. Acad. Sci. U.S.A. 77, 6822-6826
11. Hopwood, J. J. and Elliott, H. (1983) N-acetylglucosamine 6-sulfate residues in keratan sulfate and heparan sulfate are desulfated by the same enzyme. Biochem. Int. 6, 141-148
12. Fuchs, W., Beck, M. and Kresse, H. (1985) Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate. Eur. J. Biochem. 151, 551-556
13. Bernfield, M., Gotte, M., Park, P. W., Reizes, O., Fitzgerald, M. L., Lincecum J. and Zako, M. (1999) Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem. 68, 729-777
14. Funderburgh, J. L. (2000) Keratan sulfate: structure, biosynthesis, and function. Glycobiology 10, 951-958
15. Dhoot, G. K., Gustafsson, M. K., Ai, X., Sun, W., Standiford, D. M. and Emerson, Jr, C. P. (2001) Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase. Science 293, 1663-1666
16. Lundin, L., Larsson, H., Kreuger, J., Kanda, S., Lindahl, U., Salmivirta, M. and Claesson-Welsh, L. (2000) Selectively desulfated heparin inhibits fibroblast growth factor-induced mitogenicity and angiogenesis. J. Biol. Chem. 275, 24653-24660
17. Duensing, T. D., Wing, J. S. and van Putten, J. P. (1999) Sulfated polysaccharide-directed recruitment of mammalian host proteins: a novel strategy in microbial pathogenesis. Infect. Immun. 67, 4463-4468
18. Feyzi, E., Trybala, E., Bergstrom, T., Lindahl, U. and Spillmann, D. (1997) Structural requirement of heparan sulfate for interaction with herpes simplex virus type 1 virions and isolated glycoprotein C. J. Biol. Chem. 272, 24850-24857
19. Freeman, C. and Hopwood, J. J. (1992) Human glucosamine-6-sulphatase deficiency. Diagnostic enzymology towards heparin-derived trisaccharide substrates. Biochem. J. 282, 605-614
20. Robertson, D. A., Freeman, C., Nelson, P. V., Morris, C. P. and Hopwood, J. J. (1988) Human glucosamine-6-sulfatase cDNA reveals homology with steroid sulfatase. Biochem. Biophys. Res. Commun. 157, 218-224
21. Robertson, D. A., Freeman, C., Morris, C. P. and Hopwood, J. J. (1992) A cDNA clone for human glucosamine-6-sulphatase reveals differences between arylsulphatases and non-arylsulphatases. Biochem. J. 288, 539-544
22. Peterson, C. G. B., Jörnvall, H. and Venge, P. (1988) Purification and characterization of eosinophil cationic protein from normal human eosinophils. Eur. J. Haematol. 40, 415-423
23. Reissig, J. L., Stromiger, J. L. and Leloir, L. F. (1955) A modified colorimetric method for the estimation of N-acetylamino sugars. J. Biol. Chem. 217, 959-966
24. Park, J. T. and Johnson, M. J. (1949) A submicrodetermination of glucose. J. Biol. Chem. 181, 149-151
25. Rong, J., Habuchi, H., Kimata, K., Lindahl, U. and Kusche-Gullberg, M. (2000) Expression of heparan sulphate L-iduronyl 2-O-sulphotransferase in human kidney 293 cells results in increased D-glucuronyl 2-O-sulphation. Biochem. J. 346, 463-468
26. Shively, J. E. and Conrad, H. E. (1976) Formation of anhydrosugars in the chemical depolymerization of heparin. Biochemistry 7, 3932-3942
27. Olofsson, T., Olsson, I., Venge, P. and Elgefors, B. (1977) Serum myeloperoxidase and lactoferrin in neutropenia. Scand. J. Haematol. 18, 73-80
28. Xu, S. Y., Petersson, C. G., Carlson, M. and Venge, P. (1994) The development of an assay for human neutrophil lipocalin (HNL) - to be used as a specific marker of neutrophil activity in vivo and vitro. J. Immunol. Methods 171, 245-252
29. DeChatelet, L. R. and Cooper, M. R. (1970) A modified procedure for the determination of leukocyte alkaline phosphatase. Biochem. Med. 4, 61-68
30. Kjeldsen, L., Johnsen, A. H., Sengelov, H. and Borregaard, N. (1993) Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268, 10425-10432
31. Kjeldsen, L., Bainton, D. F., Sengelov, H. and Borregaard, N. (1994) Identification of neutrophil gelatinase-asociated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood 83, 799-807
32. Xu, S. Y., Carlson, M., Engström, Å., Garcia, R., Peterson, C. G. B. and Venge, P. (1994) Purification and characterization of a human neutrophil lipocalin (HNL) from the secondary granules of human neutrophils. Scand. J. Clin. Lab. Invest. 54, 365-376
33. Salmivirta, M., Lidholt, K. and Lindahl, U. (1996) Heparan sulfate: a piece of information. FASEB J. 10, 1270-1279
34. Lindahl, U., Lidholt, K., Spillmann, D. and Kjellen, L. (1994) More to "heparin" than anticoagulation. Thromb. Res. 75, 1-32
35. Rostand, K. S. and Esko, J. D. (1997) Microbial adherence to and invasion through proteoglycans. Infect. Immun. 65, 1-8