Perturbation of a lipid membrane by amphipathic peptides and its role in pore formation

European Biophysics Journal

Volumn 34, Issue 3, 2005, Pages 230-242

  Zemel, Assaf ^a   Ben Shaul, Avinoam ^a   May, Sylvio ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCARBON; PEPTIDE DERIVATIVE;

ADSORPTION; ARTICLE; CHANNEL GATING; DIMERIZATION; FORCE; LIPID MEMBRANE; MOLECULAR MODEL; OLIGOMERIZATION; PROTEIN STRUCTURE; THEORETICAL STUDY;

COMPUTER SIMULATION; DIMERIZATION; HYDROPHOBICITY; LIPID BILAYERS; MEMBRANE FLUIDITY; MEMBRANE PROTEINS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES; PERMEABILITY; PHOSPHATIDYLCHOLINES; POROSITY;

EID: 18844409111     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-004-0445-9     Document Type: Article

References (49)

1. Bak M, Bywater RP, Hohwy M, Thomsen JK, Adelhorst K, Jakobsen H, Sorensen OW, Nielsen NC (2001) Conformation of alamethicin in oriented phospholipid bilayers determined by (15)N solid-state nuclear magnetic resonance. Biophys J 81:1684-1698
2. Balgavý P, Dubničková M, Kučerka N, Kieslev MA, Yaradaikin S, Uhríková D (2001) Bilayer thickness and lipid interface area in unilamellar extruded 1,2-diacylphosphatidylcholine liposomes: a small-angle neutron scattering study. Biochim Biophys Acta 1512:40-52
3. Bechinger B (1999) The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy. Biochim Biophys Acta 1462:157-183
4. Ben-Shaul A, Gelbart WM (1994) Statistical thermodynamics of amphiphile self-assembly: structure and phase transitions in micellar solutions. In: Gelbart WM, Ben-Shaul A, Roux D (eds) Micelles, membranes, microemulsions and monolayers. Springer, New York, Ch1, pp 359-402
5. Cantor RS (2002) Size distribution of barrel-stave aggregates of membrane peptides: Influence of the bilayer lateral pressure profile. Biophys J 82:2520-2525
6. Chen L, Bassolino D, Stouch T (1997) Transmembrane helix structure, dynamics, and interactions: Multi-nanosecond molecular dynamics simulation. Biophys J 73:3-20
7. Dan N, Safran SA (1998) Effect of lipid characteristics on the structure of transmembrane proteins. Biophys J 75:1410-1414
8. Dempsey CE, Ueno S, Avison MB (2003) Enhanced membrane permeabilization and antibacterial activity of a disulfide-dimerized magainin analogue. Biochemistry 42:402-409
9. Douliez JP, Léonard A, Dufourc EJ (1995) Restatement of order parameters in biomembtanes: calculation of C-C bond order parameters from C-D quadrupolar splittings. Biophys J 68:1727-1739
10. Fattal DR, Ben-Shaul A (1993) A molecular model for lipid protein interaction in membranes: the role of hydrophobic mismatch. Biophys J 65:1795-1809
11. Fattal DR, Andelman D, Ben-Shaul A (1995) The vesicle-micelle transition in mixed lipid-surfactant systems: a molecular model. Langmuir 11:1154-1161
12. Hamm M, Kozlov MM (2000) Elastic energy of tilt and bending of fluid membranes. Eur Phys J B 3:323-335
13. He K, Ludtke SJ, Heller WT, Huang HW (1996) Mechanism of alamethicin insertion into lipid bilayers. Biophys J 71:2669-2679
14. Helfrich W (1973) Elastic properties of lipid bilayers: theory and possible experiments. Z Naturforsch 28:693-703
15. Heller WT, He K, Ludtke SJ, Harroun TA, Huang HW (1997) Effect of changing the size of lipid headgroup on peptide insertion into membranes. Biophys J 73:239-244
16. Hristova K, Wimley WC, Mishra VK, Anantharamiah GM, Segrest JP, White SH (1999) An amphipathic α-helix at the membrane interface: A structural study using a novel X-ray diffraction method. J Mol Biol 290:99-117
17. Hristova K, Dempsey CE, White SH (2001) Structure, location, and lipid perturbations of melittin at the membrane interface. Biophys J 80:801-811
18. Huang HW, Wu Y (1991) Lipid-alamethicin interactions influence alamethicin orientation. Biophys J 60:1079-1087
19. Huang HW, Chen FY, Lee MT (2004) Molecular mechanism of peptide-induced pores in membranes. Phys Rev Lett 92:198304
20. Israelachvili JN (1992) Intermolecular and surface forces, 2nd edn. Academic, New York
21. Kessel A, Ben-Tal N, May S (2001) Interactions of cholesterol with lipid bilayers: The preferred configuration and fluctuations. Biophys J 81:643-658
22. Koenig BW, Ferretti JA, Gawrisch K (1999) Site-specific deuterium order parameters and membrane-bound behavior of a peptide fragment from the intracellular domain of HIV-1 gp41. Biochemistry 38:6327-6334
23. Lin J, Baumgaertner A (2000) Stability of a melittin pore in a lipid bilayer: a molecular dynamics study. Biophys J 78:1714-1724
24. Ludtke SJ, He K, Wu Y, Huang HW (1994) Cooperative membrane insertion of magainin correlated with its cytolytic activity. Biochim Biophys Acta 1190:181-184
25. Ludtke SJ, He K, Huang HW (1995) Membrane thinning caused by magainin 2. Biochemistry 34:16764-16769
26. Ludtke SJ, He K, Heller WT, Harroun TA, Yang L, Huang HW (1996) Membrane pores induced by magainin. Biochemistry 35:13723-13728
27. Matsuzaki K, Sugishita K, Fujii N, Miyajima K (1995) Molecular basis of membrane selectivity of an antimicrobial peptide, magainin 2. Biochemistry 34:3423-3429
28. Matsuzaki K, Sugishita K, Ishibe N, Ueha M, Nakata S, Miyajima K, Epand RM (1998) Relationship of membrane curvature to the formation of pores by magainin 2. Biochemistry 37:11856-11863
29. May S (2000) Protein-induced bilayer deformations: The lipid tilt degree of freedom. Eur Biophys J 29:17-28
30. May S (2002) Membrane perturbations induced by integral proteins: role of conformational restrictions of the lipid chains. Langmuir 18:6356-6364
31. II, transition. Biophys J 76:751-767
32. May S, Ben-Shaul A (2000) A molecular model for lipid-mediated interaction between proteins in membranes. Phys Chem Chem Phys 2:4494-4502
33. Münster C, Lu J, Schinzel S, Bechinger B, Salditt T (2000) Grazing incidence x-ray diffraction of highly aligned phospholipid membranes containing the antimicrobial peptide magainin 2. Eur Biophys J Biophys Lett 28:683-688
34. Münster C, Spaar A, Bechinger B, Salditt T (2002) Magainin 2 in phospholipid bilayers: peptide orientation and lipid chain ordering studied by x-ray diffraction. Biochim biophys Acta 1562:37-44
35. Oren Z, Shai Y (1998) Mode of action of linear amphipathic alpha-helical antimicrobial peptides. Biopolymers 47:451-463
36. Rapaport D, Shai Y (1991) Interaction of fluorescently labeled pardaxin and its analogues with lipid bilayers. J Biol Chem 266:23769-23775
37. Rapaport D, Shai Y (1992) Aggregation and organization of pardaxin in phospholipid membranes. A fluorescence energy transfer study. J Biol Chem 267:6502-6509
38. Rapaport D, Peled R, Nir S, Shai Y (1996) Reversible surface aggregation in pore formation by paradaxin. Biophys J 70:2502-2512
39. Ren J, Lew S, Wang Z, London E (1999) Control of the transmembrane orientation and interhelical interactions within membranes by hydrophobic helix length. Biochemistry 38:5905-5912
40. Sansom MSP (1993) Alamethicin and related peptaibols-model ion channels. Eur Biophys J 22:105-124
41. Schwarz G, Stankowski S, Rizzo V (1986) Thermodynamic analysis of incorporation and aggregation in a membrane: application to the pore-forming peptide alamethicin. Biochim Biophys Acta 861:141-151
42. Shepherd CM, Vogel HJ, Tieleman DP (2003) Interactions of the designed antimicrobial peptide MB21 and truncated dermaseptin S3 with lipid bilayers: molecular-dynamics simulations. Biochem J 370:233-243
43. Smith R, Separovic F, Milne TJ, Whittaker A, Bennett FM, Cornell BA, Makriyannis A (1994) Structure and orientation of the pore-forming peptide, melittin, in lipid bilayers. J Mol Biol 241:456-466
44. Takei J, Remenyi A, Dempsey CE (1999) Generalized bilayer perturbation from peptide helix dimerization at membrane surfaces: vesicle lysis induced by disulphide-dimerised melittin analogues. FEBS Lett 442:11-14
45. Yang L, Weiss TM, Lehrer RI, Huang HW (2000) Crystallization of antimicrobial pores in membranes: magainin and protegrin. Biophys J 79:2002-2009
46. Yang L, Harroun TA, Weiss TM, Ding L, Huang HW (2001) Barrel-Stave model or Toroidal model? A case study on melittin pores. Biophys J 81:1475-1485
47. Zemel A, Fattal DR, Ben-Shaul A (2003) Energetics and self-assembly of amphipathic peptide pores in lipid membranes. Biophys J 84:2242-2255
48. Zemel A, Ben-Shaul A, May S (2004) Membrane perturbation induced by interfacially adsorbed peptides. Biophys J 86:3607-3619
49. Zuckermann MJ, Heimburg T (2001) Insertion and pore formation driven by adsorption of proteins onto lipid bilayer membrane-water interfaces. Biophys J 81:2458-2472