Drugs of abuse, protein phosphatases, and ERK pathway;Drogues addictives, protéine phosphatases et voie ERK

Medecine/Sciences

Volumn 21, Issue 5, 2005, Pages 453-454

  Valjent, Emmanuel ^a   Hervé, Denis ^a   Girault, Jean Antoine ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE DERIVATIVE; ANTIDEPRESSANT AGENT; CAFFEINE; CANNABIS; DOPAMINE 1 RECEPTOR; DRONABINOL; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID; NEUROLEPTIC AGENT; NICOTINE; PHOSPHOPROTEIN DARPP 32; PHOSPHOPROTEIN PHOSPHATASE;

CORPUS STRIATUM; DEPHOSPHORYLATION; DOPAMINERGIC SYSTEM; DOPAMINERGIC TRANSMISSION; DRUG ABUSE; ENZYME ACTIVATION; HIPPOCAMPUS; MOTIVATION; NOTE; NUCLEUS ACCUMBENS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYNAPSE;

CANNABIS;

EID: 18844408154     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/2005215453     Document Type: Note

References (9)

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6. Valjent E, Corvol JC, Pages C, et al. Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties. J Neurosci 2000; 20: 8701-9.
7. Valjent E, Pages C, Herve D, et al. Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain. Eur J Neurosci 2004; 19: 1826-36.
8. Valjent E, Pascoli V, Svenningsson P, et al. Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proc Natl Acad Sci USA 2005; 102: 491-6.
9. Svenningsson P, Nishi A, Fisone G, et al. DARPP-32: an integrator of neurotransmission. Annu Rev Pharmacol Toxicol 2004; 44: 269-96.