Determination by asymmetric total synthesis of the absolute configuration of lucilactaene, a cell-cycle inhibitor in p53-transfected cancer cells

Angewandte Chemie - International Edition

Volumn 44, Issue 20, 2005, Pages 3110-3115

  Yamaguchi, Junichiro ^a   Kakeya, Hideaki ^b   Uno, Takao ^a   Shoji, Mitsuru ^a   Osada, Hiroyuki ^b   Hayashi, Yujiro ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b Japan Science and Technology Agency   (Japan)

Author keywords

Asymmetric synthesis; Biosynthesis; Lucilactaene; Racemization; Total synthesis

Indexed keywords

CELL CULTURE; REACTION KINETICS; STEREOCHEMISTRY; TUMORS;

LUCILACTAENE (1); MYCELIA; NATURAL PRODUCTS; RACEMIZATION;

BIOSYNTHESIS;

ANTINEOPLASTIC AGENT; FURAN DERIVATIVE; LUCILACTAENE; PROTEIN P53; PYRROLE DERIVATIVE;

ARTICLE; BIOMIMETICS; CELL CYCLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; FUSARIUM; GENETICS; OPTICAL ROTATION; STEREOISOMERISM; SYNTHESIS;

ANTINEOPLASTIC AGENTS; BIOMIMETICS; CELL CYCLE; FURANS; FUSARIUM; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; OPTICAL ROTATION; PYRROLES; STEREOISOMERISM; TUMOR SUPPRESSOR PROTEIN P53;

EID: 18844398098     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200500060     Document Type: Article

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