A link between ALS and short residence on Guam

Neurology

Volumn 64, Issue 10, 2005, Pages 1819-1820

  Majoor Krakauer, Danielle ^a   Mulder, Paul G H ^a   Rowland, Lewis P ^b   Ottman, Ruth ^c  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NEUROLOGICAL INSTITUTE   (United States)

^c Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC PREDISPOSITION; GUAM; HUMAN; MAJOR CLINICAL STUDY; MALE; MIGRATION; PRIORITY JOURNAL; RISK ASSESSMENT; STATISTICAL ANALYSIS; UNITED STATES;

ADULT; AGE FACTORS; AGE OF ONSET; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; CASE-CONTROL STUDIES; CAUSALITY; CYCAS; DEMENTIA; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GUAM; HUMANS; MALE; MIDDLE AGED; NEUROTOXINS; PARKINSONIAN DISORDERS; RISK FACTORS; SEX FACTORS; TIME FACTORS; UNITED STATES;

EID: 18844365950     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000162030.60827.C2     Document Type: Article

References (7)

1. Garruto RM, Gajdusek C, Chen KM. Amyotrophic lateral sclerosis among Chamorro migrants from Guam. Ann Neurol 1980;8:612-619.
2. Zhang ZX, Anderson DW, Mantel N, Roman GC. Motor neuron disease on Guam: temporal occurrence, 1941-85. Acta Neurol Scand 1995;92: 299-307.
3. Cox PA, Sacks OW. Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam. Neurology 2002;58:956-959.
4. Banack SA, Cox PA. Biomagnification of cycad neurotoxins in flying foxes: implications for ALS-PDC in Guam. Neurology 2003;61:387-389.
5. Majoor-Krakauer D, Ottman R, Johnson WG, Rowland LP. Familial aggregation of amyotrophic lateral sclerosis, dementia, and Parkinson's disease: evidence of shared genetic susceptibility. Neurology 1994;44: 1872-1877.
6. Brody JA, Edgar AH, Gillespie MM. Amyotrophic lateral sclerosis. No increase among US construction workers in Guam. JAMA 1978;240:551-560.
7. Kurtzke JF, Beebe GW. Epidemiology of amyotrophic lateral sclerosis: 1. A case-control comparison based on ALS deaths. Neurology 1980; 30:453-462.