New aspects of secretory otitis media, eustachian tube function and middle ear gas

Ear, Nose and Throat Journal

Volumn 77, Issue 9, 1998, Pages

  Ovesen, Therese ^a,b   Børglum, Jens D ^a,b  

^a Aarhus University Hospital ^*

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE;

ARTICLE; AUDITORY TUBE; GAS FLOW; HUMAN; HYPEROXIA; MICROBIOLOGY; MIDDLE EAR; MIDDLE EAR MUCOSA; MIDDLE EAR PRESSURE; PATHOGENESIS; SECRETORY OTITIS MEDIA; TUBE;

EID: 18744433372     PISSN: 01455613     EISSN: None     Source Type: Journal    
DOI: 10.1177/014556139807700914     Document Type: Article

References (68)

1. Bluestone CD. Current concepts in otolaryngology. Otitis media in children: To treat or not to treat? N Engl J Med 1982;306:1399-1404.
2. Møller P. Tympanosclerosis of the ear drum in children. Int J Pediatr Otorhinolaryngol 1984;7:247-56.
3. Møller P. Hearing, middle ear pressure and otopathology in a cleft palate population. Acta Otolaryngol 1981;92:521-8.
4. Lildholdt T, Felding JU. Tympanosclerosis. Proceedings of the Third International Symposium on Recent Advances in Otitis Media. Toronto, Philadelphia: BC Decker Inc., 1984;51-2.
5. Møller H, Tos M. Point and period prevalence of otitis media with effusion evaluated by daily tympanometry. J Laryngol Otol 1990;104:937-41.
6. Fiellau-Nikolajsen M. Tympanometry and secretory otitis media. Acta Otolaryngol 1983;Suppl 394.
7. Cantekin EI, Casselbrant ML, Doyle WJ, et al. Prospective study of eustachian tube function and otitis media. Proceedings of the Fourth International Symposium on Recent Advances in Otitis Media. Toronto, Philadelphia: B.C. Decker Inc., 1987;58-60.
8. Casselbrant ML, Cantekin EI, Dirkmaat DC, et al. Experimental paralysis of tensor velipalatini muscle. Acta Otolaryngol 1988;106: 171-8.
9. Ovesen T, Paaske PB, Blegvad S, et al. Histological examination of the rabbit middle ear in secretory otitis media with and without a ventilation tube. APMIS 1992;100:839-44.
10. Ovesen T, Paaske PB, Ledet T, et al. Immunohistochemical quantitation of collagen types I, II, IV, and V in the ventilated and non-ventilated rabbit middle ear with otitis media with effusion Eur Arch Otorhinolaryngol 1994;251:137-42.
11. Sadé J. Gas exchange. Proceedings of the Third Extraordinary International Symposium on Recent Advances in Otitis Media. 1997;87-92.
12. Mills RP. A bacteriological study of the middle ear and upper respiratory tract in children with chronic secretory otitis media Clin Otolaryngol 1985;10:335-41.
13. Cabenda SI. Serous otitis media (SOM): A bacteriological study of the ear canal and the middle ear. Int J Pediatr Otorhinolaryngol 1988;16:119-24.
14. Kamme C. Secretory otitis media: Microbiology of the middle ear and the nasopharynx. Scand J Infect Dis 1984;16:291-6.
15. Sorensen CH Nasopharyngeal bacteriology and secretory otitis media in young children. Acta Otolaryngol 1988;105:126-31.
16. Bunse T. A bacteriological study of otitis media with effusion: Concurrent coagulase-negative staphylococcal infections in the middle ear Eur Arch Otorhinolaryngol 1987;243:387-91.
17. Ovesen T, Elbrönd O. The microbiology of middle ear fluid and its relationship to the course of secretory otitis media. In press.
18. Iino Y, Yuasa R, Kaneko Y, et al. Prognosis and endotoxin contents in middle ear effusions in cases after acute otitis media. Acta Otolaryngol 1987;435:85-9.
19. Teele DW, Klein JO, Rosner BA. Epidemiology of otitis media in children. Ann Otol Rhinol Laryngol 1980;89:5-6.
20. Marchant CD, Shurin PA, Turczyk VA. Course and outcome of otitis media in early infancy: A prospective study. J Pediatr 1984; 104:826-31.
21. Howie VM, Ploussard JH, Sloyer J. The "otitis-prone" condition. Am J Dis Child 1975;129:676-8.
22. Jinnin T, Dake Y, Kusumoto T. et al. Quantitative determination of bacterial endotoxin in middle ear effusions by chromogenic substrate method. Auris Nasus Larynx 1985;12:97-9.
23. DeMaria TF. Endotoxin and otitis media. Ann Otol Rhinol Laryngol 1988;97:31-4.
24. Iino Y, Kaneko Y, Takasaka T. Endotoxin in middle ear effusions tested with limulus assay. Acta Otolaryngol 1985;100:42-50.
25. DeMaria TF, Prior RB, Briggs BR, et al. Endotoxin in middle-ear effusion from patients with chronic otitis media with effusion. J Clin Microbiol 1984;20:15-7.
26. DeMaria TF, Tatsuji Y, Lim DJ. Quantitative cytologic and histologic changes in the middle ear after injection of nontypable Haemophilus influenzae endotoxin. Proceedings of the Fourth International Symposium on Recent Advances in Otitis Media. Toronto, Philadelphia: BC Decker Inc., 1987;320-3.
27. Ovesen T, Ledet T. Bacteria and endotoxin in middle ear fluid and their correlation to the course of secretory otitis media. Clin Otolaryngol 1992;17:531-4.
28. Ovesen T, Gaihede M, Elbrönd O. The influence of endotoxin upon middle ear fibroblasts cultured in normal middle ear gas and atmospheric air. APMIS 1994;102:743-52.
29. Felding JU, Rasmussen JB, Lildholdt T. Gas composition of the normal and the ventilated middle ear cavity. Scand J Clin Lab Invest 1987;47:31-41.
30. Jackler RK. Experimental evidence against middle ear oxygen absorption [letter]. Laryngoscope 1985;95:1281-2.
31. Elner A. Gas diffusion through the tympanic membrane. Acta Otolaryngol 1970;69:185-91.
32. Ovesen T. Implications of middle ear hyperoxia induced by ventilation tubes in otitis media with effusion. APMIS 1995; Suppl 54;103:1-36.
33. Ovesen T, Gaihede M, Schousboe LP, et al. Atmospheric air vs. normal middle ear gas: Effects on in vitro growth and collagen synthesis in normal middle ear fibroblasts. In Vitro Cell Devel Biol 1994;30A:249-55.
34. Schousboe LP, Ovesen T. Effect of oxygen tension on in vitro growth and synthesis of rabbit middle ear epithelium and auditory meatal epithelium. Int J Pediatr Otolaryngol. In press.
35. Clark JM, Lambertsen CJ. Pulmonary oxygen toxicity: A review. Pharmacol Rev 1971;23:37-133.
36. Ehrenkranz RA, Ablow RC, Warshaw JB. Oxygen toxicity. Clin Perinatol 1978;5:437-50.
37. Deneke SM, Fanburg BL. Normobaric oxygen toxicity of the lung. N Engl J Med 1980;303:76-86.
38. Jackson RM. Pulmonary oxygen toxicity. Chest 1985;88:900-5.
39. Cadenas E. Biochemistry of oxygen toxicity. Annu Rev Biochem 1989;58:79-110.
40. Oberley LW. Superoxide dismutase. Vol II. Florida: CRS Press, 1982.
41. Bulkley GB. The role of oxygen free radicals in human disease processes. Surgery 1983;94:407-12.
42. Weisiger RA. Oxygen radicals and ischemic tissue injury. Gastroenterology 1986;90:494-6.
43. Jackson CV, Mickelson JK, Pope TK, et al. O, free radical-mediated myocardial and vascular dysfunction. Am J Physiol 1986; 251:H1225-31.
44. Bass DA, Olbrantz P, Szejda P, et al. Subpopulations of neutrophils with increased oxidative product formation in blood of patients with infection. J Immunol 1986,136:860-6.
45. Repine JE, Tate RM. Oxygen radicals and lung edema. Physiologist 1983;26:177-81.
46. Krieger BP, Loomis WH, Czer GT, et al. Mechanisms of interaction between oxygen and granulocytes in hyperoxic lung injury. J Appl Physiol 1985;58:1326-30.
47. Massaro D. Oxygen: Toxicity and tolerance. Hosp Pract 1985;21:95-101.
48. McCord MJ. Free radicals and inflammation: Protection of synovial fluid by superoxide dismutase. Science 1974;185:529-31.
49. Baggiolini M, Wymann MP Turning on the respiratory burst. Trends Biochem Sci 1990; 15-69-72.
50. 2. J Appl Physiol 1987;62:2230-6.
51. Adamson IYR, Young L, Bowden DH. Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis. Am J Pathol 1988;130:377-83.
52. Holm BA, Notter RH, Siegle J, et al. Pulmonary physiological and surfactant changes during injury and recovery from hyperoxia. J Appl Physiol 1985;59:1402-9.
53. Riley DJ, Kerr JS, Yu SY. et al. Pulmonary oxygen toxicity: Connective tissue changes during injury and repair. Chest 1983; 83:98-98.
54. Sandholm RE, Johnson K, Killen P, et al. Alveolar injury by oxygen metabolites alters the composition of extracellular matrix. Chest 1983;83:42-33.
55. Jones R, Zapol WM, Reid L. Pulmonary arterial wall injury and remodelling by hyperoxia. Chest 1983;83:40-2S.
56. Greenwald RA, Moy WW. Inhibition of collagen gelation by action of the superoxide radical. Arthritis Rheum 1979;22:251-60.
57. Ward PH, Maldonado M, Moreno M, et al. Oxygen-derived free radicals mediate the cutaneous necrotizing vasculitis induced by epinephrine in endotoxin-primed rabbits. J Infect Dis 1990;61: 1020-2.
58. Berg JT, Smith RM. Protection against hyperoxia by serum from endotoxin treated rats: Absence of superoxide dismutase induction. Proc Soc Exp Biol Med 1988;187:117-22.
59. Olson NC. Grizzle MK, Anderson DL. Effects of polyethylene glycolsuperoxide dismutase and catalase on endotoxemia in pigs. J Appl Physiol 1987;63:1526-32.
60. Hazinski TA, Kennedy KA, France ML, et al. Pulmonary O, toxicity in lambs: Physiological and biochemical effects of endotoxin infusion. J Appl Physiol 1988;65:1579-85.
61. Shiki Y, Meyrick BO, Brigham KL, et al. Endotoxin increases superoxide dismutase in cultured bovine pulmonary endothelial cells. Am J Physiol 1987;252:C436-40.
62. Berg JT, Allison RC, Prasad VR, et al. Endotoxin protection of rats from pulmonary oxygen toxicity: Possible cytokine involvement. J Appl Physiol 1990;68:549-53.
63. Ovesen T, Børglum JD. Superoxide dismutase in middle ear fluid from children with secretory otitis media. Acta Otolaryngol 1992;112:1017-24.
64. Ovesen T, Ledet T, Elbrönd O. Superoxide dismutase in in vitro cultures of middle ear fibroblasts from the rabbit. Eur Arch Otorhinolaryngol 1994;251:319-24.
65. 2 toxicity by N-acetylcysteine. Eur Respir J 1989;2:116-26.
66. Kharazmi A, Nielsen H, Schiøtz PO. N-acetylcysteine inhibits human neutrophil and monocyte chemotaxis and oxidative metabolism. Int J Immunopharmacol 1988;10:39-46.
67. Ovesen T, Paaske PB, Elbrönd O. Local application of N-acetylcysteine in secretory otitis media in rabbits. Clin Otolaryngol 1992;17:327-31.
68. Ovesen T, Gaihede M, Ledet T. The effect of N-acetylcysteine on the in vitro growth of normal rabbit middle ear fibroblasts. Clin Otolaryngol 1993;18:400-5.