No effect of long-term valproate therapy on thyroid and parathyroid functions in children

International Journal of Neuroscience

Volumn 112, Issue 11, 2002, Pages 1371-1374

  Çaksen, Hüseyin ^a,b   Dülger, Haluk ^a   Cesur, Yaşar ^a   Odabaş, Dursun ^a   Tuncer, Oǧuz ^a   Ataş, Bülent ^a  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

^b Yuzuncu Yil Univ Fac of Medicine ^*  (Turkey)

Author keywords

Parathyroid; Thyroid; Valproate

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; OSTEOCALCIN; PHOSPHORUS; THYROID HORMONE; VALPROIC ACID;

ADOLESCENT; ARTICLE; BLOOD; CHILD; DRUG EFFECT; EPILEPSY; HUMAN; INFANT; INSTRUMENTATION; PARATHYROID GLAND; PRESCHOOL CHILD; SPECTROPHOTOMETRY; THYROID GLAND; TIME;

ADOLESCENT; ALKALINE PHOSPHATASE; CALCIUM; CHILD; CHILD, PRESCHOOL; EPILEPSY; HUMANS; INFANT; OSTEOCALCIN; PARATHYROID GLANDS; PHOSPHORUS; SPECTROPHOTOMETRY; THYROID GLAND; THYROID HORMONES; TIME; VALPROIC ACID;

EID: 18744409146     PISSN: 00207454     EISSN: None     Source Type: Journal    
DOI: 10.1080/00207450290158269     Document Type: Article

References (9)

1. Bentsen, K. D., Gram, L., & Veje, A. (1983). Serum thyroid hormones and blood folic acid during monotherapy with carbamazepine or valproate. A controlled study. Acta Neurologica Scandinavica, 67, 235-241.
2. Conran, M. J., Kearney, P. J., Callaghan, M. N., Murphy, D., & Goggin, T. (1985). Hypothalamic pituitary function testing on children receiving carbamazepine or sodium valproate. Epilepsia, 26, 585-588.
3. Demir, E., & Aysun, S. (2000). Weight gain associated with valproate in childhood. Pediatric Neurology, 22, 361-364.
4. Eiris-Punal, J., Del Rio-Garma, M., Del Rio-Garma, M. C., Lojo-Rocamonde, S., Novo-Rodriguez, I., & Castro-Gago, M. (1999). Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism. Epilepsia, 40, 1761-1766.
5. Isojarvi, J. I., Laatikainen, T. J., Knip, M., Pakarinen, A. J., Juntunen, K. T., & Myllyla, V. V. (1996). Obesity and endocrine diseases in women taking valprate for epilepsy. Annals of Neurology, 39, 579-584.
6. Isojarvi, J. I., Turkka, J., Pakarinen, A. J., Kotila, M., Rattya, J., & Myllyla, V. V. (2001). Thyroid function in men taking carbamazopine, oxcarbazepine, or valproate for epilepsy. Epilepsia, 42, 930-934.
7. Pena Grinan, M. J., Lluch Fernandez, M. D., Montoya Garcia, M. J., Ramos Sanchez, I., & Perez Cano, R. (1991). Phosphorus-calcium metabolism in children under prolonged treatment with anticonvulsants (II). (in Spanish) Annales Espanoles Pediatria, 35, 169-172.
8. Tanaka, K., Kodama, S., Yokoyama, S., Komatsu, M., Konishi, H., Momota, K., & Matsuo, T. (1987). Thyroid function in children with long-term anticonvulsant treatment. Pediatr Neuroscience, 13, 90-94.
9. Verrotti, A., Basciani, F., Morresi, S., Morgese, G., & Chiarelli, F. (2001). Thyroid hormones in epileptic children receiving carbamazepine and valproic acid. Pediatric Neurology, 25, 43-46.