-
3
-
-
0018188885
-
The acute toxicity of single, oral doses of 1,1-dichloroethylene in the fasted, male rat: effect of induction and inhibition of microsomal enzyme activities on mortality
-
Andersen, M. E., Jones, R. A. and Jenkins L. J. 1978: The acute toxicity of single, oral doses of 1,1-dichloroethylene in the fasted, male rat: effect of induction and inhibition of microsomal enzyme activities on mortality. Toxicology and Applied Pharmacology 46, 227-234.
-
(1978)
Toxicology and Applied Pharmacology
, vol.46
, pp. 227-234
-
-
Andersen, M.E.1
Jones, R.A.2
Jenkins, L.J.3
-
4
-
-
0023195488
-
Quantitative evaluation of the metabolic interactions between trichloroethylene and 1,1-dichloroethylene in vivo using gas uptake methods
-
Andersen, M. E., Gargas, M. L., Clewell, H. J. D. and Severyn, K. M. 1987: Quantitative evaluation of the metabolic interactions between trichloroethylene and 1,1-dichloroethylene in vivo using gas uptake methods. Toxicology and Applied Pharmacology 89, 149-157.
-
(1987)
Toxicology and Applied Pharmacology
, vol.89
, pp. 149-157
-
-
Andersen, M.E.1
Gargas, M.L.2
Clewell, H.J.D.3
Severyn, K.M.4
-
5
-
-
0027248652
-
Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high
-
Badger, T. M., Huang, J., Ronis, M. and Lumpkin, C. K. 1993: Induction of cytochrome P450 2E1 during chronic ethanol exposure occurs via transcription of the CYP 2E1 gene when blood alcohol concentrations are high. Biochemical and Biophysical Research Communications 190, 780-785.
-
(1993)
Biochemical and Biophysical Research Communications
, vol.190
, pp. 780-785
-
-
Badger, T.M.1
Huang, J.2
Ronis, M.3
Lumpkin, C.K.4
-
6
-
-
0028930174
-
Chloroethylene mixtures: pharmacokinetic modeling and in vitro metabolism of vinyl chloride, trichloroethylene, and trans- 1,2-dichloroethylene in rat
-
Barton, H. A., Creech, J. R., Godin, C. S. et al. 1995: Chloroethylene mixtures: pharmacokinetic modeling and in vitro metabolism of vinyl chloride, trichloroethylene, and trans- 1,2-dichloroethylene in rat. Toxicology and Applied Pharmacology 130, 237-247.
-
(1995)
Toxicology and Applied Pharmacology
, vol.130
, pp. 237-247
-
-
Barton, H.A.1
Creech, J.R.2
Godin, C.S.3
-
7
-
-
0031943857
-
Gender- and age-specific cytotoxic susceptibility to benzene metabolites in vitro
-
Corti, M. and Snyder, C. A. 1998: Gender- and age-specific cytotoxic susceptibility to benzene metabolites in vitro. Toxicological Sciences 41, 42-48.
-
(1998)
Toxicological Sciences
, vol.41
, pp. 42-48
-
-
Corti, M.1
Snyder, C.A.2
-
8
-
-
84927734465
-
-
Special Report No. 13, August 1997. Brussels: European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC).
-
ECETOC, 1997: Occupational exposure limits for hydrocarbon solvents. Special Report No. 13, August 1997. Brussels: European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC).
-
(1997)
Occupational exposure limits for hydrocarbon solvents
-
-
-
9
-
-
0032849028
-
Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans
-
Emery, M. G., Jubert, C., Thummel, K. E. and Kharasch, E. D. 1999: Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans. Journal of Pharmacology and Experimental Therapeutics 291, 213-219.
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.291
, pp. 213-219
-
-
Emery, M.G.1
Jubert, C.2
Thummel, K.E.3
Kharasch, E.D.4
-
10
-
-
0029128788
-
Age but not gender selectively affects expression of individual cytochrome P450 proteins in human liver
-
George, J., Byth, K. and Farrell, G. C. 1995a: Age but not gender selectively affects expression of individual cytochrome P450 proteins in human liver. Biochemical Pharmacology 50, 727-730.
-
(1995)
Biochemical Pharmacology
, vol.50
, pp. 727-730
-
-
George, J.1
Byth, K.2
Farrell, G.C.3
-
11
-
-
0028801475
-
Differential alterations of cytochrome P450 proteins in livers from patients with severe chronic liver disease
-
George, J., Murray, M., Byth, K. and Farrell, G. C. 1995b: Differential alterations of cytochrome P450 proteins in livers from patients with severe chronic liver disease. Hepatology 21, 120-128.
-
(1995)
Hepatology
, vol.21
, pp. 120-128
-
-
George, J.1
Murray, M.2
Byth, K.3
Farrell, G.C.4
-
12
-
-
0026035519
-
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
-
Guengerich, F. P., Kim, D. H. and Iwasaki, M. 1991: Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chemical Research in Toxicology 4, 168-179.
-
(1991)
Chemical Research in Toxicology
, vol.4
, pp. 168-179
-
-
Guengerich, F.P.1
Kim, D.H.2
Iwasaki, M.3
-
13
-
-
0027318789
-
Exposure to various benzene derivatives differently induces cytochromes P450 2B1 and P450 2E1 in rat liver
-
Gut, I., Terelius, Y., Frantik, E., Linhart, I., Soucek, P., Filipcova, B. and Kluckova, H. 1993: Exposure to various benzene derivatives differently induces cytochromes P450 2B1 and P450 2E1 in rat liver. Archives of Toxicology 67, 237-243.
-
(1993)
Archives of Toxicology
, vol.67
, pp. 237-243
-
-
Gut, I.1
Terelius, Y.2
Frantik, E.3
Linhart, I.4
Soucek, P.5
Filipcova, B.6
Kluckova, H.7
-
14
-
-
0021677858
-
Induction of the ethanol-inducible form of rabbit liver microsomal cytochrome P-450 by inhibitors of alcohol dehydrogenase
-
Ingelman-Sundberg, M. and Jornvall, H. 1984: Induction of the ethanol-inducible form of rabbit liver microsomal cytochrome P-450 by inhibitors of alcohol dehydrogenase. Biochemical and Biophysical Research Communications 124, 375-382.
-
(1984)
Biochemical and Biophysical Research Communications
, vol.124
, pp. 375-382
-
-
Ingelman-Sundberg, M.1
Jornvall, H.2
-
15
-
-
0030799328
-
Ethnic differences in biological monitoring of several organic solvents. II. A simulation study with a physiologically based pharmacokinetic model
-
Jang, J. Y. and Droz, P. O. 1997: Ethnic differences in biological monitoring of several organic solvents. II. A simulation study with a physiologically based pharmacokinetic model. International Archives of Occupational and En-vironmental Health 70, 41-50.
-
(1997)
International Archives of Occupational and En-vironmental Health
, vol.70
, pp. 41-50
-
-
Jang, J.Y.1
Droz, P.O.2
-
16
-
-
0030992920
-
Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats
-
Jin, L. and Baillie, T. A. 1997: Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats. Chemical Research in Toxicology 10, 318-327.
-
(1997)
Chemical Research in Toxicology
, vol.10
, pp. 318-327
-
-
Jin, L.1
Baillie, T.A.2
-
17
-
-
0027234689
-
Enzyme induction by ethanol consumption affects the pharmacokinetics of inhaled m-xylene only at high levels of exposure
-
Kaneko, T., Wang, P. Y. and Sato, A. 1993: Enzyme induction by ethanol consumption affects the pharmacokinetics of inhaled m-xylene only at high levels of exposure. Archives of Toxicology 67, 473-477.
-
(1993)
Archives of Toxicology
, vol.67
, pp. 473-477
-
-
Kaneko, T.1
Wang, P.Y.2
Sato, A.3
-
18
-
-
0032573512
-
Influence of gender and acetone pretreatment on benzene metabolism in mice exposed by nose-only inhalation
-
Kenyon, E. M., Seaton, M. J., Himmelstein, M. W., Asgharian, B. and Medinsky, M. A. 1998: Influence of gender and acetone pretreatment on benzene metabolism in mice exposed by nose-only inhalation. Journal of Toxicology and Environmental Health 55, 421-443.
-
(1998)
Journal of Toxicology and Environmental Health
, vol.55
, pp. 421-443
-
-
Kenyon, E.M.1
Seaton, M.J.2
Himmelstein, M.W.3
Asgharian, B.4
Medinsky, M.A.5
-
19
-
-
0023790333
-
Pyridine induction of cytochrome P- 450 in the rat: role of P-450j (alcohol-inducible form) in pyridine N-oxidation
-
Kim, S. G., Williams, D. E., Schuetz, E. G., Guzelian, P. S. and Novak, R. F. 1988: Pyridine induction of cytochrome P- 450 in the rat: role of P-450j (alcohol-inducible form) in pyridine N-oxidation. Journal of Pharmacology and Experimental Therapeutics 246, 1175-1182.
-
(1988)
Journal of Pharmacology and Experimental Therapeutics
, vol.246
, pp. 1175-1182
-
-
Kim, S.G.1
Williams, D.E.2
Schuetz, E.G.3
Guzelian, P.S.4
Novak, R.F.5
-
21
-
-
0028852923
-
Assessment of the accuracy of material safety data sheets
-
Kolp, P. W., Williams, P. L. and Burtan, R. C. 1995: Assessment of the accuracy of material safety data sheets. American Industrial Hygiene Association Journal 56, 178-183.
-
(1995)
American Industrial Hygiene Association Journal
, vol.56
, pp. 178-183
-
-
Kolp, P.W.1
Williams, P.L.2
Burtan, R.C.3
-
22
-
-
0028608120
-
Physiologically based pharmacokinetic analyses of simple mixtures
-
Krishnan, K., Clewell, H. J. and Andersen, M. E. 1994: Physiologically based pharmacokinetic analyses of simple mixtures. Environmental Health Perspectives 102 (Suppl 9), 151-155.
-
(1994)
Environmental Health Perspectives
, vol.102
, pp. 151-155
-
-
Krishnan, K.1
Clewell, H.J.2
Andersen, M.E.3
-
23
-
-
0026774035
-
Use of physiologically based pharmacokinetic models to establish biological exposure indexes
-
Leung, H. W. 1992: Use of physiologically based pharmacokinetic models to establish biological exposure indexes. American Industrial Hygiene Association Journal 53, 369-374.
-
(1992)
American Industrial Hygiene Association Journal
, vol.53
, pp. 369-374
-
-
Leung, H.W.1
-
24
-
-
18744379626
-
-
62 FR 1494, January 10, 1997. Washington, DC: US Occupational Safety and Health Administration (OSHA).
-
OSHA, 1997. Methylene Chloride VI. Quantitative Risk Assessment. 62 FR 1494, January 10, 1997. Washington, DC: US Occupational Safety and Health Administration (OSHA).
-
(1997)
Methylene Chloride VI. Quantitative Risk Assessment
-
-
-
25
-
-
84998179335
-
-
Air Contaminants: 29 CFR 1910.1000 (d): Occupational Safety and Health Administration
-
OSHA, 2004. Air Contaminants: 29 CFR 1910.1000 (d): Occupational Safety and Health Administration.
-
(2004)
-
-
-
26
-
-
0024832058
-
Modulation of cytochrome P450 isozymes in human liver, by ethanol and drug intake
-
Perrot, N., Nalpas, B., Yang, C. S. and Beaune, P. H. 1989: Modulation of cytochrome P450 isozymes in human liver, by ethanol and drug intake. European Journal of Clinical Investigations 19, 549-555.
-
(1989)
European Journal of Clinical Investigations
, vol.19
, pp. 549-555
-
-
Perrot, N.1
Nalpas, B.2
Yang, C.S.3
Beaune, P.H.4
-
27
-
-
0030036795
-
Interindividual variations in susceptibility and sensitivity: linking risk assessment and risk management
-
Preston, R. J. 1996: Interindividual variations in susceptibility and sensitivity: linking risk assessment and risk management. Toxicology 111, 331-341.
-
(1996)
Toxicology
, vol.111
, pp. 331-341
-
-
Preston, R.J.1
-
28
-
-
0025290203
-
In vivo metabolic interactions of benzene and toluene
-
Purcell, K. J., Cason, G. H., Gargas, M. L., Andersen, M. E. and Travis, C. C. 1990: In vivo metabolic interactions of benzene and toluene. Toxicology Letters 52, 141-152.
-
(1990)
Toxicology Letters
, vol.52
, pp. 141-152
-
-
Purcell, K.J.1
Cason, G.H.2
Gargas, M.L.3
Andersen, M.E.4
Travis, C.C.5
-
29
-
-
0021279862
-
A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans
-
Ramsey, J. C. and Andersen, M. E. 1984: A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicology and Applied Pharmacology 73, 159-175.
-
(1984)
Toxicology and Applied Pharmacology
, vol.73
, pp. 159-175
-
-
Ramsey, J.C.1
Andersen, M.E.2
-
30
-
-
0029621945
-
Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1
-
Raucy, J. L. 1995: Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1. Toxicology 105, 217-224.
-
(1995)
Toxicology
, vol.105
, pp. 217-224
-
-
Raucy, J.L.1
-
31
-
-
0025805616
-
Induction of cytochrome P450IIE1 in the obese overfed rat
-
Raucy, J. L., Lasker, J. M., Kraner, J. C., Salazar, D. E., Lieber, C. S. and Corcoran, G. B. 1991: Induction of cytochrome P450IIE1 in the obese overfed rat. Molecular Pharmacology 39, 275-280.
-
(1991)
Molecular Pharmacology
, vol.39
, pp. 275-280
-
-
Raucy, J.L.1
Lasker, J.M.2
Kraner, J.C.3
Salazar, D.E.4
Lieber, C.S.5
Corcoran, G.B.6
-
32
-
-
0032527044
-
Mechanism-based inactivation of cytochromes P450 2E1 and 2B1 by 5-phenyl-1-pentyne
-
Roberts, E. S., Alworth, W. L. and Hollenberg, P. F. 1998: Mechanism-based inactivation of cytochromes P450 2E1 and 2B1 by 5-phenyl-1-pentyne. Archives of Biochemistry and Biophysics 354, 295-302.
-
(1998)
Archives of Biochemistry and Biophysics
, vol.354
, pp. 295-302
-
-
Roberts, E.S.1
Alworth, W.L.2
Hollenberg, P.F.3
-
33
-
-
0025739599
-
Effects of consumption of ethanol on the biological monitoring of exposure to organic solvent vapours: a simulation study with trichloroethylene
-
Sato, A., Endoh, K., Kaneko, T. and Johanson, G. 1991: Effects of consumption of ethanol on the biological monitoring of exposure to organic solvent vapours: a simulation study with trichloroethylene. British Journal of Industrial Medicine 48, 548-556.
-
(1991)
British Journal of Industrial Medicine
, vol.48
, pp. 548-556
-
-
Sato, A.1
Endoh, K.2
Kaneko, T.3
Johanson, G.4
-
34
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada, T., Yamazaki, H., Mimura, M., Inui, Y. and Guengerich, F. P. 1994: Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Journal of Pharmacology and Experimental Therapeutics 270, 414-423.
-
(1994)
Journal of Pharmacology and Experimental Therapeutics
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
35
-
-
0028619860
-
Parameter variability and the interpretation of physiologically based pharmacokinetic modeling results
-
Spear, R. C. and Bois, F. Y. 1994: Parameter variability and the interpretation of physiologically based pharmacokinetic modeling results. Environmental Health Perspectives 102 (Suppl 11), 61-66.
-
(1994)
Environmental Health Perspectives
, vol.102
, pp. 61-66
-
-
Spear, R.C.1
Bois, F.Y.2
-
36
-
-
0028024393
-
Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese
-
Stephens, E. A., Taylor, J. A., Kaplan, N., Yang, C. H., Hsieh, L. L., Lucier, G. W. and Bell, D. A. 1994: Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese. Pharmacogenetics 4, 185-192.
-
(1994)
Pharmacogenetics
, vol.4
, pp. 185-192
-
-
Stephens, E.A.1
Taylor, J.A.2
Kaplan, N.3
Yang, C.H.4
Hsieh, L.L.5
Lucier, G.W.6
Bell, D.A.7
-
37
-
-
0029016437
-
Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans
-
Tardif, R., Lapare, S., Charest-Tardif, G., Brodeur, J. and Krishnan, K. 1995: Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans. Risk Analysis 15, 335-342.
-
(1995)
Risk Analysis
, vol.15
, pp. 335-342
-
-
Tardif, R.1
Lapare, S.2
Charest-Tardif, G.3
Brodeur, J.4
Krishnan, K.5
-
38
-
-
26844526389
-
Incorporating Monte Carlo simulation into physiologically based pharmacokinetic models using advanced continuous simulation language (ACSL): a computational method
-
Thomas, R. S., Lytle, W. E., Keefe, T. J., Constan, A. A. and Yang, R. S. 1996: Incorporating Monte Carlo simulation into physiologically based pharmacokinetic models using advanced continuous simulation language (ACSL): a computational method. Fundamental and Applied Toxicology 31, 19-28.
-
(1996)
Fundamental and Applied Toxicology
, vol.31
, pp. 19-28
-
-
Thomas, R.S.1
Lytle, W.E.2
Keefe, T.J.3
Constan, A.A.4
Yang, R.S.5
-
39
-
-
0003672085
-
-
EPA/600/P-92/003C, April, 1996. Washington, DC: US Environmental Protection Agency.
-
USEPA, 1996: Proposed guidelines for carcinogen risk assessment. EPA/600/P-92/003C, April, 1996. Washington, DC: US Environmental Protection Agency.
-
(1996)
Proposed guidelines for carcinogen risk assessment
-
-
-
40
-
-
0003427614
-
-
EPA/630/R-97/001, March, 1997. Washington, DC: USEPA.
-
USEPA, 1997: Guiding Principles for Monte Carlo Analysis. EPA/630/R-97/001, March, 1997. Washington, DC: USEPA.
-
(1997)
Guiding Principles for Monte Carlo Analysis
-
-
-
41
-
-
0029090599
-
The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures
-
Yang, R. S., el-Masri, H. A., Thomas, R. S. et al. 1995: The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures. Toxicology Letters 79: 193-200.
-
(1995)
Toxicology Letters
, vol.79
, pp. 193-200
-
-
Yang, R.S.1
el-Masri, H.A.2
Thomas, R.S.3
|