A new calcipotriol/betamethasone dipropionate formulation (Daivobet™) is an effective once-daily treatment for psoriasis vulgaris

Dermatology

Volumn 205, Issue 4, 2002, Pages 389-393

  Kaufmann, R ^a   Bibby, A J ^b   Bissonnette, R ^e   Cambazard, F ^f   Chu, A C ^c   Decroix, J ^g   Douglas, W S ^d   Lowson, D ^b   Mascaro, J M ^h   Murphy, G M ⁱ   Stymne, B ^b  

^a GOETHE UNIVERSITY   (Germany)

^b Leo Pharmaceuticals   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d MONKLANDS HOSPITAL   (United Kingdom)

^e INNOVADERM RESEARCH   (Canada)

^f HÔPITAL NORD   (France)

^g Hospital Clinic i Provincial ^*

^h HOSPITAL CLÍNIC   (Spain)

ⁱ BEAUMONT HOSPITAL   (Ireland)

Author keywords

Betamethasone dipropionate; Calcipotriol; Combination therapy; Psoriasis

Indexed keywords

BETAMETHASONE DIPROPIONATE; BETAMETHASONE DIPROPIONATE PLUS CALCIPOTRIOL; CALCIPOTRIOL; DRUG VEHICLE;

ADULT; ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG FORMULATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OINTMENT; PRIORITY JOURNAL; PSORIASIS VULGARIS; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SIDE EFFECT;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BETAMETHASONE; CALCITRIOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; OINTMENTS; PATIENT SATISFACTION; PSORIASIS; REFERENCE VALUES; SEVERITY OF ILLNESS INDEX; SWEDEN; TREATMENT OUTCOME;

EID: 18744389433     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000066440     Document Type: Article

References (19)

1. Greaves MW, Weinstein GD: Treatment of psoriasis. N Engl J Med 1995;332:581-588.
2. Nevitt GJ, Hutchinson PE: Psoriasis in the community: Prevalence, severity and patients' beliefs and attitudes towards the disease. Br J Dermatol 1996;135:533-537.
3. Finlay AY, Coles EC: The effect of severe psoriasis on the quality of life of 369 patients. Br J Dermatol 1995;132:236-244.
4. Berth-Jones J, Chu AC, Dodd WAH, Ganpule M, Griffiths W, Haydey R, Klaber M, Murray S, Rogers S, Jurgensen H: A multi-centre, parallel-group comparison of calcipotriol ointment and short-contact dithranol therapy in chronic plaque psoriasis. Br J Dermatol 1992;127:266-271.
5. Ellis JP, Griffiths WAD, Klaber MR: Long-term treatment of chronic plaque psoriasis with calcipotriol ointment in patients unresponsive to short-contact dithranol. Eur J Clin Res 1995;7:247-257.
6. Kragballe K, Gjertsen BT, de Hoop D, Karlsmark T, van de Kerkhof PCM, Larko O, Nieboer C, Roed-Petersen J, Strand A, Tikjøb G: Double-blind, right/left comparison of calcipotriol and betamethasone valerate in treatment of psoriasis vulgaris. Lancet 1991;337:193-196.
7. Cunliffe WJ, Berth-Jones J, Claudy A, Fairiss G, Goldin D, Gratton D, Henderson C, Holden C, Maddin S, Ortonne J, Young M: Comparative study of calcipotriol (MC 903) ointment and betamethasone 17-valerate ointment in patients with psoriasis vulgaris. J Am Acad Dermatol 1992;26:736-743.
8. Kragballe K, Barnes L, Hamberg KJ, Hutchinson P, Murphy F, Moller S, Ruzicka T, van de Kerkhof P: Calcipotriol cream with or without concurrent topical corticosteroid in psoriasis: Tolerability and efficacy. Br J Dermatol 1998;139:649-654.
9. Lebwohl M, Siskin SB, Epinette W, Breneman D, Funicella T, Kalb R, Moore J: A multicenter trial of calcipotriene ointment and halobetasol ointment compared with either agent alone for the treatment of psoriasis. J Am Acad Dermatol 1996;35:268-269.
10. Ruzicka T, Lorenz B: Comparison of calcipotriol monotherapy and a combination of calcipotriol and betamethasone valerate after 2 weeks' treatment with calcipotriol in the topical therapy of psoriasis vulgaris: A multicentre, double-blind, randomized study. Br J Dermatol 1998;138:254-258.
11. Patel B, Siskin S, Krazmien R, Lebwohl M: Compatibility of calcipotriene with other topical medications. J Am Acad Dermatol 1998;38:1010-1011.
12. Roberts DT: Comparison of fluticasone propionate ointment, 0.005%, and betamethasone 17,21-dipropionate ointment, 0.05%, in the treatment of psoriasis. Cutis 1996;57:27-31.
13. Shupack JL, Jondreau L, Kenny C, Stiller MJ: Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis. Dermatology 1993;186:129-132.
14. Chuang TY, Samson CR: Clinical efficacy and safety of augmented betamethasone dipropionate ointment and diflorasone diacetate ointment for psoriasis - A multicentre, randomized, double-blinded study. J Dermatol Treat 1991;2:63-66.
15. Papp KA, Guenther L, Boyden B, Larsen FG, Harvima RJ, Guilhou JJ, Kaufmann R, Rogers S, van de Kerkhof PCM, Hanssen LI, Tegner E, Burg G, Talbot D, Chu A: Early onset of action and efficacy of a combination of calcipotriene and betamethasone dipropionate in the treatment of psoriasis. J Am Acad Dermatol, in press.
16. Douglas WS, Poulin Y, Decroix J, Ortonne JP, Mrowietz U, Gulliver W, Krogstad AL, Larsen FG, Iglesias L, Buckley C, Bibby AJ: A new calcipotriol/betamethasone formulation with rapid onset of action was superior to monotherapy with betamethasone dipropionate or calcipotriol in psoriasis vulgaris. Acta Derm Venereol 2002;82:131-135.
17. Gollnick H, Menke T: Current experience with tacalcitol ointment in the treatment of psoriasis. Curr Med Res Opin 1998;14:213-218.
18. Lagos BR, Maibach HI: Frequency of application of topical corticosteroids: An overview. Br J Dermatol 1998;139:763-766.
19. Woodford R, Haigh JM, Barry BW: Possible dosage regimens for topical steroids, assessed by vasoconstrictor assays using multiple applications. Dermatologica 1983;166:136-140.