Mitochondria from cultured cells derived from normal and thiamine-responsive megaloblastic anemia individuals efficiently import thiamine diphosphate

BMC Biochemistry

Volumn 3, Issue , 2002, Pages 1-8

  Song, Qilin ^a   Singleton, Charles K ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCARBOXYLASE; THIAMINE; VITAMIN BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL ISOLATION; CELL MEMBRANE; FIBROBLAST; HUMAN; HUMAN CELL; LYMPHOBLAST; MEGALOBLASTIC ANEMIA; MITOCHONDRION; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; OVARY CELL; VITAMIN INTAKE; ANIMAL; CELL LINE; CHO CELL; CYTOLOGY; HAMSTER; KINETICS; LYMPHOCYTE; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA;

ANEMIA, MEGALOBLASTIC; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CHO CELLS; CRICETINAE; HUMANS; KINETICS; LYMPHOCYTES; MITOCHONDRIA; THIAMINE; THIAMINE PYROPHOSPHATE; TUMOR CELLS, CULTURED;

EID: 18744389159     PISSN: 14712091     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2091-3-8     Document Type: Article

References (28)

1. Hazell AS, Todd KG, Butterworth RF: Mechanisms of neuronal cell death in Wernicke's encephalopathy. Metab. Brain Disease 1998, 13:97-122
2. Singleton CK, Martin PR: Molecular mechanisms of thiamine utilization. Curr. Mol. Med. 2001, 1:197-207
3. Bettendorff L, Wins P: Mechanism of thiamine transport in neuroblastoma cells. J. Biol. Chem. 1994, 269:14379-14385
4. Bettendorff L: Thiamine homeostasis in neuroblastoma cells. Neurochem. Int. 1995, 26:295-302
5. Bettendorff L, Wins P, Lesourd M: Subcellular localization and compartmentation of thiamine derivatives in rat brain. Biochim. Biophys. Acta 1994, 1222:1-6
6. Pekovich SR, Martin PR, Poggi V, Singleton CK: Sensitivity to thiamine deficiency in cultured human cells is dependent on cell type and is greatly increased in cells from thiamine-responsive megaloblastic anemia patients. J. Nutri. Biochem. 1998, 9:215-222
7. Diaz G, Banikazemi M, Oishi K, Desnick RJ, Gelb B: Mutations in a new gene encoding a thiamine transporter cause thiamine-responsive megaloblastic anemia syndrome. Nat Genet 1999, 22:309-312
8. Dutta B, Huang W, Molero M, kekuda R, Leibach F, Devoe L, Ganapathy V, Prasad P: Cloning of the human thiamine transporter, a member of the folate transporer family. J. Biol. Chem. 1999, 45:31925-31929
9. Fleming J, Tartaglini E, Steinkamp M, Schorderet D, Cohen N, Neufeld E: The gene mutated in thiamine-responsive anemia with diabetes and deafness (TRMA) encodes a functional thiamine transporter. Nat Genet 1999, 22:305-308
10. Labay V, Raz T, Baron D, Mandel H, Williams H, t Barrett, Szargel R, McDonald L, Shalata A, Nosaka K, Gregory S, Cohen N: Mutations in SLC19A2 cause thiamine-responsive megaloblastic anemia associated with diabetes mellitus and deafness. Nat Genet 1999, 22:300-304
11. Rindi G, Casirola D, Poggi V, Vizia BD, Patrini C, Laforenza U: Thiamine transport by erythrocytes and ghosts in thiamine responsive megaloblastic anaemia. J. Inhert. Metab. Dis. 1992, 15:231-242
12. Rindi G, Patrini C, Laforenza U, Mandel H, Berant M, Viana MB, Poggi V, Zarra AMF: Further studies on erythrocyte thiamine trans-portand phosphorylation in seven patients with thiamine-responsive megaloblastic anemia. J. Inhert. Metab. Dis. 1994, 17:667-677
13. Barile M, Passarella S, Quagliariello E: Uptake of thiamine by isolated rat liver mitochondria. Biochem. Biophys. Res. Commun. 1986, 141:466-473
14. Barile M, Passarella S, Quangliariello E: Thiamine pyrophosphate uptake into isolated rat liver mitochondria. Arch. Biochem. Biophys. 1990, 280:352-357
15. Deus B, Blum H: Biochim. Biophys. Acta 1970, 219:489-492
16. Voskoboyev AI, Averin VA: Vopr. Med. Khim. 1981, 27:239-243
17. Bettendorff L: The compartmentation of phosphorylated thiamine derivatives in cultured neuroblastoma cells. Biochim. Biophys. Acta 1994, 1222:7-14
18. Tallaksen CME, Bohmer T, Bell H, Karlsen J: Concomitant determination of thiamine and its phosphate esters in human blood and serum by high performance liquid chromatography. J. Chromat. 1991, 564:127-136
19. Barile M, Valenti D, Brizio C, Quagliariello E, Passarella S: Rat liver mitochondria can hydrolze thiamine pyrophosphate to thiamine monophosphate which can cross the mitochondrial membrane in a carrier-mediated process. FEBS Let. 1998, 435:6-10
20. Rindi G: Some aspects of thiamine transport in mammals. J. Nutri. Sci. Vitamin. 1992, S12:379-382
21. Deus B: Assay of thiamine pyrophosphokinase. Meth. Enzym. 1970, 18:221-225
22. Zhao R, Gao F, Wang Y, Diaz GA, Gelb BD, Goldman ID: Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells. J. Biol. Chem. 2000, 276:1114-1118
23. Titus S, Moran R: Retrovirally Mediated Complementation of the glyB Phenotype: Cloning of a human gene encoding the carrier for entry of folates into mitochondria. J. Biol. Chem. 2000, 275:36811-36817
24. Ross RA, Spengler BA, Biedler JL: Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 1983, 71:741-747
25. Singleton CK: Identification and characterization of the thiamine transporter gene of Saccharomyces cerevisiae. Gene 1997, 199:111-121
26. Horne D, Holloway R, Said H: Uptake of 5-formyltetrahydrofolate in isolated rat liver mitochondria is carrier-mediated. J. Nutr. 1992, 122:2204-2209
27. Pederson P, Greenwalt J, Feynafarje B, Hullihen J, Decker G, Soper J, Bustamante E: Preparation and characterization of mitochondria and submitochondrial particlesof rat liver and liver-derived tissues. Meth. Cell Biol. 1978, 20:411-481
28. Said H, McAlister-Henn L, Mohammadkhani R, Horne D: Uptake of biotin by isolated rat liver mitochondria. Am. J. Physiol. 1992, 263:G81-G86