Immune activation and radioprotection by Propolis

American Journal of Chinese Medicine

Volumn 33, Issue 2, 2005, Pages 231-240

  Takagi, Yasuyuki ^a   Choi, In Sook ^a   Yamashita, Takenori ^a   Nakamura, Takashi ^a   Suzuki, Ikukatsu ^a   Hasegawa, Takeo ^a   Oshima, Masami ^a   Gu, Yeun Hwa ^a  

^a SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

CD4; CD8; IgG; IgM; Propolis; Radiation Protection; T Lymphocyte

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PROPOLIS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; HELPER CELL; IMMUNOGLOBULIN PRODUCTION; IMMUNOSTIMULATION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; RADIATION PROTECTION; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; WHOLE BODY RADIATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNITY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MACROPHAGES; MALE; MICE; MICE, INBRED C3H; PROPOLIS; RADIATION-PROTECTIVE AGENTS; T-LYMPHOCYTE SUBSETS; WHOLE-BODY IRRADIATION;

EID: 18744386417     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X05002886     Document Type: Article

References (25)

1. Abbas, A.K., K.M. Murphy and A. Sher. Functional diversity of helper T lymphocytes. Nature 383: 787-793, 1996.
2. Andreassen, C.N., C. Grau and J.C. Lindegaard. Chemical radioprotection: A critical review of amifostine as a cytoprotector in radiotherapy. Semin. Radiat. Oncol. 13: 62-72, 2003.
3. Ansorge, S., D. Reinhold and U. Lendeckel. Propolis and some of its constituents down-regulate DNA synthesis and inflammatory cytokine production but induce TGF-beta1 production of human immune cells. Z. Naturforsch. 58: 580-589, 2003.
4. Bankova, V., M.C. Marcucci, S. Simova, N. Nikolova, A. Kujumgiev and S. Popov. Antibacterial diterpenic acids from Brazilian Propolis. Z. Naturforsch. 51: 277-280, 1996.
5. Bankova, V.S., J.M.G. Boudourova-Krasteva and J.M. Sforcin. Phytochemical evidence for the plant origin of Brazilian Propolis from São Paulo State. Z. Naturforsch. 54: 401-405, 1999.
6. Banskota, A.H., Y. Tezuka, J.K. Prasain, K. Matsushige, I. Saiki and S. Kadota. Chemical constituents of Brazilian Propolis and their cytotoxic activities. J. Nat. Prod. 61: 896-900, 1998.
7. Beuscher, N., C. Bodinet, D. Neumann-Haefelin, A. Marston and K. Hostettmann. Antiviral activity of African medicinal plants. J. Ethnopharmacol. 42: 101-109, 1994.
8. Blonska, M., J. Bronikowska, G. Pietsz, Z.P. Czuba, S. Scheller and W. Krol. Effects of ethanol extract of Propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages. J. Ethnopharmacol. 91: 25-30, 2004.
9. Bousquet, J., J.L. Menardo and F.B. Michel. Allergy in beekeepers. Allergol. Immunopathol. 10: 395-398, 1982.
10. Burdock, G.A. Review of the biological properties and toxicity of bee Propolis (Propolis). Food Chem. Toxicol. 36: 347-363, 1998.
11. Duarte, S., H. Koo, W.H. Bowen, M.F. Hayashibara, J.A. Cury, M. Ikegaki and P.L. Rosalen. Effect of a novel type of Propolis and its chemical fractions on glucosyltransferases and on growth and adherence of mutans Streptococci. Biol. Pharm. Bull. 26: 527-531, 2003.
12. Fukuhara, S., N. Takagi, T. Ikeda, M. Ono, A.M. Nafady, T. Nohara, H. Sugimoto, S. Doi and H. Yamada. Two novel long-chain alkanoic acid esters of lupeol from alecrim-propolis, Chem. Pharm. Bull. 50: 439-440, 2002.
13. Georgieva, R., R. Tsevi, K. Kossev, R. Kusheva, M. Balgjiska, R. Petrova, V. Tenchova, I. Gitsov and K. Troev. Immobilization of aminothiols on poly (oxyalkylene phosphates). Formation of poly (oxyethylene phosphates)/cysteamine complexes and their radioprotective efficiency. Int. J. Med. Chem. 45: 5797-5801, 2002.
14. Harish, Z., A. Rubinstein, M. Golodner, M. Elmaliah and Y. Mizrachi. Suppression of HIV-1 replication by propolis and its immunoregulatory effect. Drugs Exp. Clin. Res. 23: 89-96, 1997.
15. Ilhan, A., O. Akyol, A. Gurel, F. Armutcu, M. Iraz and E. Oztas. Protective effects of caffeic acid phenethyl ester against experimental allergic encephalomyelitis-induced oxidative stress in rats. Free Radic. Biol. Med. 37: 386-394, 2004.
16. Jorgensen, C., V. Brocks, J. Bang, F.S. Jorgensen and L. Ronsbro. Treatment of severe fetal chylothorax associated with pronounced hydrops with intrapleural injection of OK-432. Ultrasound Obstet. Gynecol. 21: 66-69, 2003.
17. Kong, X., Y. Hu, R. Rui, D. Wang and X. Li. Effects of Chinese herbal medicinal ingredients on peripheral lymphocyte proliferation and serum antibody titer after vaccination in chicken. Int. Immunopharmacol. 4: 975-982, 2004.
18. Kristensen, N.N., A.N. Madsen, A.R. Thomsen and J.P. Christensen. Cytokine production by virus-specific CD8(+) T cells varies with activation state and localization, but not with TCR avidity. J. Gen. Virol. 85: 1703-1712, 2004.
19. Melliou, E. and I. Chinon. Chemical analysis and antimicrobial activity of Greek Propolis. Planta Med. 70: 515-519, 2004.
20. Mosmann, T.R. and S. Sad. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol. Today 17: 138-146, 1996.
21. Paganelli, R., E. Scala, F. Aiuti and M. Fiorilli. B-cell help by Tc2 cells. Immunol. Today 19: 142, 1998.
22. Rehman, J., J.M. Dillow, S.M. Carter, J. Chou, B. Le and A.S. Maisel. Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis. Immunol. Lett. 68: 391-395, 1999.
23. Rininger, J.A., S. Kickner, P. Chigurupati, A. McLean and Z. Franck. Immunopharmacological activity of Echinacea, preparations following simulated digestion on murine macrophages and human peripheral blood mononuclear cells. J. Leukoc. Biol. 68: 503-510, 2000.
24. Suzuki, L., I. Hayashi, T. Takaki, D.S. Groveman and Y. Fujimiya. Antitumor and anticytopenic effects of aqueous extracts of propolis in combination with chemotherapeutic agents. Cancer Biother. Radiopharm. 17: 553-562, 2002.
25. Yang, K., E. Azoulay, L. Attalah, J.R. Zahar, A. Van De Louw, C. Cerf, C.J. Soussy, P. Duvaldestin, L. Brochard, C. Brun-Buisson, A. Harf and C. Delclaux. Bactericidal activity response of blood neutrophils from critically ill patients to in vitro granulocyte colony-stimulating factor stimulation. Intensive Care Med. 29: 396-402, 2003.